BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 18042941)

  • 21. Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins.
    Smith S; Hyde M; Pincus MR
    Protein J; 2005 Aug; 24(6):391-8. PubMed ID: 16323045
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A Sos proteomimetic as a pan-Ras inhibitor.
    Hong SH; Yoo DY; Conway L; Richards-Corke KC; Parker CG; Arora PS
    Proc Natl Acad Sci U S A; 2021 May; 118(18):. PubMed ID: 33926964
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.
    Moghadamchargari Z; Shirzadeh M; Liu C; Schrecke S; Packianathan C; Russell DH; Zhao M; Laganowsky A
    Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723061
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.
    Roose JP; Mollenauer M; Gupta VA; Stone J; Weiss A
    Mol Cell Biol; 2005 Jun; 25(11):4426-41. PubMed ID: 15899849
    [TBL] [Abstract][Full Text] [Related]  

  • 25. New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function.
    Silver SJ; Chen F; Doyon L; Zink AW; Rebay I
    Genesis; 2004 Aug; 39(4):263-72. PubMed ID: 15286999
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Allosteric gating of Son of sevenless activity by the histone domain.
    Yadav KK; Bar-Sagi D
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3436-40. PubMed ID: 20133694
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Development of Noonan syndrome by deregulation of allosteric SOS autoactivation.
    Umutesi HG; Hoang HM; Johnson HE; Nam K; Heo J
    J Biol Chem; 2020 Sep; 295(39):13651-13663. PubMed ID: 32753483
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.
    Margarit SM; Sondermann H; Hall BE; Nagar B; Hoelz A; Pirruccello M; Bar-Sagi D; Kuriyan J
    Cell; 2003 Mar; 112(5):685-95. PubMed ID: 12628188
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Feedback activation of neurofibromin terminates growth factor-induced Ras activation.
    Hennig A; Markwart R; Wolff K; Schubert K; Cui Y; Prior IA; Esparza-Franco MA; Ladds G; Rubio I
    Cell Commun Signal; 2016 Feb; 14():5. PubMed ID: 26861207
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Prenylation of Ras facilitates hSOS1-promoted nucleotide exchange, upon Ras binding to the regulatory site.
    Pechlivanis M; Ringel R; Popkirova B; Kuhlmann J
    Biochemistry; 2007 May; 46(18):5341-8. PubMed ID: 17437339
    [TBL] [Abstract][Full Text] [Related]  

  • 31. An orthosteric inhibitor of the Ras-Sos interaction.
    Patgiri A; Yadav KK; Arora PS; Bar-Sagi D
    Nat Chem Biol; 2011 Jul; 7(9):585-7. PubMed ID: 21765406
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
    Iwig JS; Vercoulen Y; Das R; Barros T; Limnander A; Che Y; Pelton JG; Wemmer DE; Roose JP; Kuriyan J
    Elife; 2013 Jul; 2():e00813. PubMed ID: 23908768
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines.
    Watanabe T; Shinohara N; Moriya K; Sazawa A; Kobayashi Y; Ogiso Y; Takiguchi M; Yasuda J; Koyanagi T; Kuzumaki N; Hashimoto A
    IUBMB Life; 2000 Apr; 49(4):317-20. PubMed ID: 10995035
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Raf-1 is involved in the regulation of the interaction between guanine nucleotide exchange factor and Ha-ras. Evidences for a function of Raf-1 and phosphatidylinositol 3-kinase upstream to Ras.
    Giglione C; Parmeggiani A
    J Biol Chem; 1998 Dec; 273(52):34737-44. PubMed ID: 9856997
    [TBL] [Abstract][Full Text] [Related]  

  • 35. In vivo functional analysis of the Ras exchange factor son of sevenless.
    Karlovich CA; Bonfini L; McCollam L; Rogge RD; Daga A; Czech MP; Banerjee U
    Science; 1995 Apr; 268(5210):576-9. PubMed ID: 7725106
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless.
    McCollam L; Bonfini L; Karlovich CA; Conway BR; Kozma LM; Banerjee U; Czech MP
    J Biol Chem; 1995 Jul; 270(27):15954-7. PubMed ID: 7608150
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.
    Lee YK; Low-Nam ST; Chung JK; Hansen SD; Lam HYM; Alvarez S; Groves JT
    Nat Commun; 2017 Apr; 8():15061. PubMed ID: 28452363
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The structural basis of the activation of Ras by Sos.
    Boriack-Sjodin PA; Margarit SM; Bar-Sagi D; Kuriyan J
    Nature; 1998 Jul; 394(6691):337-43. PubMed ID: 9690470
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Allosteric autoactivation of SOS and its kinetic mechanism.
    Hoang HM; Umutesi HG; Heo J
    Small GTPases; 2021 Jan; 12(1):44-59. PubMed ID: 30983499
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
    Gureasko J; Kuchment O; Makino DL; Sondermann H; Bar-Sagi D; Kuriyan J
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3430-5. PubMed ID: 20133692
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.