BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 18045061)

  • 1. Synthetic SRC-kinase domain inhibitors and their structural requirements.
    Schenone S; Manetti F; Botta M
    Anticancer Agents Med Chem; 2007 Nov; 7(6):660-80. PubMed ID: 18045061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors.
    Roskoski R
    Pharmacol Res; 2015 Apr; 94():9-25. PubMed ID: 25662515
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
    Dalgarno D; Stehle T; Narula S; Schelling P; van Schravendijk MR; Adams S; Andrade L; Keats J; Ram M; Jin L; Grossman T; MacNeil I; Metcalf C; Shakespeare W; Wang Y; Keenan T; Sundaramoorthi R; Bohacek R; Weigele M; Sawyer T
    Chem Biol Drug Des; 2006 Jan; 67(1):46-57. PubMed ID: 16492148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SRC family kinases as potential therapeutic targets for malignancies and immunological disorders.
    Benati D; Baldari CT
    Curr Med Chem; 2008; 15(12):1154-65. PubMed ID: 18473810
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel patented SRC kinase inhibitor.
    Lu XL; Liu XY; Cao X; Jiao BH
    Curr Med Chem; 2012; 19(12):1821-9. PubMed ID: 22414081
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.
    Ma JG; Huang H; Chen SM; Chen Y; Xin XL; Lin LP; Ding J; Liu H; Meng LH
    Breast Cancer Res Treat; 2011 Nov; 130(1):85-96. PubMed ID: 21181437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies.
    Schittenhelm MM; Shiraga S; Schroeder A; Corbin AS; Griffith D; Lee FY; Bokemeyer C; Deininger MW; Druker BJ; Heinrich MC
    Cancer Res; 2006 Jan; 66(1):473-81. PubMed ID: 16397263
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SRC kinase inhibitors: an update on patented compounds.
    Schenone S; Brullo C; Musumeci F; Radi M; Castagnolo D
    Curr Med Chem; 2011; 18(33):5061-78. PubMed ID: 22050754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo.
    Jallal H; Valentino ML; Chen G; Boschelli F; Ali S; Rabbani SA
    Cancer Res; 2007 Feb; 67(4):1580-8. PubMed ID: 17308097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy.
    Johnson FM; Gallick GE
    Anticancer Agents Med Chem; 2007 Nov; 7(6):651-9. PubMed ID: 18045060
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
    Wilson MB; Schreiner SJ; Choi HJ; Kamens J; Smithgall TE
    Oncogene; 2002 Nov; 21(53):8075-88. PubMed ID: 12444544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosine Kinase Activation and Conformational Flexibility: Lessons from Src-Family Tyrosine Kinases.
    Meng Y; Pond MP; Roux B
    Acc Chem Res; 2017 May; 50(5):1193-1201. PubMed ID: 28426203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance.
    Azam M; Nardi V; Shakespeare WC; Metcalf CA; Bohacek RS; Wang Y; Sundaramoorthi R; Sliz P; Veach DR; Bornmann WG; Clarkson B; Dalgarno DC; Sawyer TK; Daley GQ
    Proc Natl Acad Sci U S A; 2006 Jun; 103(24):9244-9. PubMed ID: 16754879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.
    Radi M; Brullo C; Crespan E; Tintori C; Musumeci F; Biava M; Schenone S; Dreassi E; Zamperini C; Maga G; Pagano D; Angelucci A; Bologna M; Botta M
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5928-33. PubMed ID: 21856155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells.
    Remsing Rix LL; Rix U; Colinge J; Hantschel O; Bennett KL; Stranzl T; Müller A; Baumgartner C; Valent P; Augustin M; Till JH; Superti-Furga G
    Leukemia; 2009 Mar; 23(3):477-85. PubMed ID: 19039322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors.
    Wang Y; Shakespeare WC; Huang WS; Sundaramoorthi R; Lentini S; Das S; Liu S; Banda G; Wen D; Zhu X; Xu Q; Keats J; Wang F; Wardwell S; Ning Y; Snodgrass JT; Broudy MI; Russian K; Dalgarno D; Clackson T; Sawyer TK
    Bioorg Med Chem Lett; 2008 Sep; 18(17):4907-12. PubMed ID: 18691885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
    Zhu X; Kim JL; Newcomb JR; Rose PE; Stover DR; Toledo LM; Zhao H; Morgenstern KA
    Structure; 1999 Jun; 7(6):651-61. PubMed ID: 10404594
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for selective inhibition of Src family kinases by PP1.
    Liu Y; Bishop A; Witucki L; Kraybill B; Shimizu E; Tsien J; Ubersax J; Blethrow J; Morgan DO; Shokat KM
    Chem Biol; 1999 Sep; 6(9):671-8. PubMed ID: 10467133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors.
    Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnerta H; Ungefroren H
    Anticancer Agents Med Chem; 2017; 17(10):1351-1356. PubMed ID: 28044939
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.
    Huang WS; Zhu X; Wang Y; Azam M; Wen D; Sundaramoorthi R; Thomas RM; Liu S; Banda G; Lentini SP; Das S; Xu Q; Keats J; Wang F; Wardwell S; Ning Y; Snodgrass JT; Broudy MI; Russian K; Daley GQ; Iuliucci J; Dalgarno DC; Clackson T; Sawyer TK; Shakespeare WC
    J Med Chem; 2009 Aug; 52(15):4743-56. PubMed ID: 19572547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.