BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 18045970)

  • 1. Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells.
    Lob S; Konigsrainer A; Schafer R; Rammensee HG; Opelz G; Terness P
    Blood; 2008 Feb; 111(4):2152-4. PubMed ID: 18045970
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism.
    Löb S; Königsrainer A; Zieker D; Brücher BL; Rammensee HG; Opelz G; Terness P
    Cancer Immunol Immunother; 2009 Jan; 58(1):153-7. PubMed ID: 18418598
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer.
    Qian F; Villella J; Wallace PK; Mhawech-Fauceglia P; Tario JD; Andrews C; Matsuzaki J; Valmori D; Ayyoub M; Frederick PJ; Beck A; Liao J; Cheney R; Moysich K; Lele S; Shrikant P; Old LJ; Odunsi K
    Cancer Res; 2009 Jul; 69(13):5498-504. PubMed ID: 19491279
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.
    Metz R; Duhadaway JB; Kamasani U; Laury-Kleintop L; Muller AJ; Prendergast GC
    Cancer Res; 2007 Aug; 67(15):7082-7. PubMed ID: 17671174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells.
    Sun T; Chen XH; Tang ZD; Cai J; Wang XY; Wang SC; Li ZL
    Mol Cell Biochem; 2010 Sep; 342(1-2):29-34. PubMed ID: 20424892
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation.
    Qian F; Liao J; Villella J; Edwards R; Kalinski P; Lele S; Shrikant P; Odunsi K
    Cancer Immunol Immunother; 2012 Nov; 61(11):2013-20. PubMed ID: 22527253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses.
    Hou DY; Muller AJ; Sharma MD; DuHadaway J; Banerjee T; Johnson M; Mellor AL; Prendergast GC; Munn DH
    Cancer Res; 2007 Jan; 67(2):792-801. PubMed ID: 17234791
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Indoleamine 2, 3-dioxygenase (IDO) is essential for dendritic cell activation and chemotactic responsiveness to chemokines.
    Hwang SL; Chung NP; Chan JK; Lin CL
    Cell Res; 2005 Mar; 15(3):167-75. PubMed ID: 15780178
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan.
    Yuasa HJ; Ball HJ; Austin CJ; Hunt NH
    Comp Biochem Physiol B Biochem Mol Biol; 2010 Sep; 157(1):10-5. PubMed ID: 20399882
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Indolamine 2,3-dioxygenase expression by monocytes and dendritic cell populations in hepatitis C patients.
    Schulz S; Landi A; Garg R; Wilson JA; van Drunen Littel-van den Hurk S
    Clin Exp Immunol; 2015 Jun; 180(3):484-98. PubMed ID: 25605587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.
    Opitz CA; Litzenburger UM; Opitz U; Sahm F; Ochs K; Lutz C; Wick W; Platten M
    PLoS One; 2011; 6(5):e19823. PubMed ID: 21625531
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of indoleamine 2,3-dioxygenase by stereoisomers of 1-methyl tryptophan in an experimental graft-versus-tumor model.
    Lim JY; Lee SE; Park G; Choi EY; Min CK
    Exp Hematol; 2014 Oct; 42(10):862-6.e3. PubMed ID: 24971697
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells.
    El Kholy NM; Sallam MM; Ahmed MB; Sallam RM; Asfour IA; Hammouda JA; Habib HZ; Abu-Zahra F
    Med Oncol; 2011 Mar; 28(1):270-8. PubMed ID: 20300979
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.
    Austin CJ; Mailu BM; Maghzal GJ; Sanchez-Perez A; Rahlfs S; Zocher K; Yuasa HJ; Arthur JW; Becker K; Stocker R; Hunt NH; Ball HJ
    Amino Acids; 2010 Jul; 39(2):565-78. PubMed ID: 20140689
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective inhibition of IDO1, D-1-methyl-tryptophan (D-1MT), effectively increased EpCAM/CD3-bispecific BiTE antibody MT110 efficacy against IDO1
    Hong R; Zhou Y; Tian X; Wang L; Wu X
    Int Immunopharmacol; 2018 Jan; 54():118-124. PubMed ID: 29128855
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice.
    Nakamura N; Hara T; Shimizu M; Mabuchi R; Nagano J; Ohno T; Kochi T; Kubota M; Shirakami Y; Goto N; Ito H; Saito K; Tanaka T; Moriwaki H; Tsurumi H
    Int J Hematol; 2015 Sep; 102(3):327-34. PubMed ID: 26243621
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular evolution and characterization of fungal indoleamine 2,3-dioxygenases.
    Yuasa HJ; Ball HJ
    J Mol Evol; 2011 Feb; 72(2):160-8. PubMed ID: 21170645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.
    Hanihara M; Kawataki T; Oh-Oka K; Mitsuka K; Nakao A; Kinouchi H
    J Neurosurg; 2016 Jun; 124(6):1594-601. PubMed ID: 26636389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IDO inhibitor synergized with radiotherapy to delay tumor growth by reversing T cell exhaustion.
    Liu M; Li Z; Yao W; Zeng X; Wang L; Cheng J; Ma B; Zhang R; Min W; Wang H
    Mol Med Rep; 2020 Jan; 21(1):445-453. PubMed ID: 31746428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.
    Ball HJ; Yuasa HJ; Austin CJ; Weiser S; Hunt NH
    Int J Biochem Cell Biol; 2009 Mar; 41(3):467-71. PubMed ID: 18282734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.