BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1133 related articles for article (PubMed ID: 18047345)

  • 1. The dinuclear Zn(II) complex catalyzed cyclization of a series of 2-hydroxypropyl aryl phosphate RNA models: progressive change in mechanism from rate-limiting P-O bond cleavage to substrate binding.
    Bunn SE; Liu CT; Lu ZL; Neverov AA; Brown RS
    J Am Chem Soc; 2007 Dec; 129(51):16238-48. PubMed ID: 18047345
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid three-step cleavage of RNA and DNA model systems promoted by a dinuclear Cu(II) complex in methanol. energetic origins of the catalytic efficacy.
    Lu ZL; Liu CT; Neverov AA; Brown RS
    J Am Chem Soc; 2007 Sep; 129(37):11642-52. PubMed ID: 17715924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A simple DNase model system comprising a dinuclear Zn(II) complex in methanol accelerates the cleavage of a series of methyl aryl phosphate diesters by 10(11)-10(13).
    Neverov AA; Liu CT; Bunn SE; Edwards D; White CJ; Melnychuk SA; Brown RS
    J Am Chem Soc; 2008 May; 130(20):6639-49. PubMed ID: 18479083
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage of an RNA model catalyzed by dinuclear Zn(II) complexes containing rate-accelerating pendants. Comparison of the catalytic benefits of H-bonding and hydrophobic substituents.
    Mohamed MF; Brown RS
    J Org Chem; 2010 Dec; 75(24):8471-7. PubMed ID: 21087029
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biomimetic cleavage of RNA models promoted by a dinuclear Zn(II) complex in ethanol. Greater than 30 kcal/mol stabilization of the transition state for cleavage of a phosphate diester.
    Liu CT; Neverov AA; Brown RS
    J Am Chem Soc; 2008 Dec; 130(49):16711-20. PubMed ID: 19554695
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.
    Mohamed MF; Neverov AA; Brown RS
    Inorg Chem; 2009 Dec; 48(23):11425-33. PubMed ID: 19874005
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Physical and kinetic analysis of the cooperative role of metal ions in catalysis of phosphodiester cleavage by a dinuclear Zn(II) complex.
    Iranzo O; Kovalevsky AY; Morrow JR; Richard JP
    J Am Chem Soc; 2003 Feb; 125(7):1988-93. PubMed ID: 12580627
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside.
    O'Donoghue A; Pyun SY; Yang MY; Morrow JR; Richard JP
    J Am Chem Soc; 2006 Feb; 128(5):1615-21. PubMed ID: 16448134
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isostructural dinuclear phenoxo-/acetato-bridged manganese(II), cobalt(II), and zinc(II) complexes with labile sites: kinetics of transesterification of 2-hydroxypropyl-p-nitrophenylphosphate.
    Arora H; Barman SK; Lloret F; Mukherjee R
    Inorg Chem; 2012 May; 51(10):5539-53. PubMed ID: 22536852
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity studies on the cleavage of an RNA analogue by a potent dinuclear metal ion catalyst: effect of changing the metal ion.
    Iranzo O; Richard JP; Morrow JR
    Inorg Chem; 2004 Mar; 43(5):1743-50. PubMed ID: 14989667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperativity between metal ions in the cleavage of phosphate diesters and RNA by dinuclear Zn(II) catalysts.
    Iranzo O; Elmer T; Richard JP; Morrow JR
    Inorg Chem; 2003 Dec; 42(24):7737-46. PubMed ID: 14632489
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combination of a dinuclear Zn2+ complex and a medium effect exerts a 10(12)-fold rate enhancement of cleavage of an RNA and DNA model system.
    Neverov AA; Lu ZL; Maxwell CI; Mohamed MF; White CJ; Tsang JS; Brown RS
    J Am Chem Soc; 2006 Dec; 128(50):16398-405. PubMed ID: 17165797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A minimalist approach to understanding the efficiency of mononuclear Zn(II) complexes as catalysts of cleavage of an RNA analog.
    Mathews RA; Rossiter CS; Morrow JR; Richard JP
    Dalton Trans; 2007 Sep; (34):3804-11. PubMed ID: 17712447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dinuclear Zn(II) complex catalyzed phosphodiester cleavage proceeds via a concerted mechanism: a density functional theory study.
    Gao H; Ke Z; DeYonker NJ; Wang J; Xu H; Mao ZW; Phillips DL; Zhao C
    J Am Chem Soc; 2011 Mar; 133(9):2904-15. PubMed ID: 21319769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Leaving group assistance in the La3+-catalyzed cleavage of dimethyl (o-methoxycarbonyl)aryl phosphate triesters in methanol.
    Edwards DR; Liu CT; Garrett GE; Neverov AA; Brown RS
    J Am Chem Soc; 2009 Sep; 131(38):13738-48. PubMed ID: 19736937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solvent induced cooperativity of Zn(II) complexes cleaving a phosphate diester RNA analog in methanol.
    Mohamed MF; Sánchez-Lombardo I; Neverov AA; Brown RS
    Org Biomol Chem; 2012 Jan; 10(3):631-9. PubMed ID: 22116167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A reductionist biomimetic model system that demonstrates highly effective Zn(II)-catalyzed cleavage of an RNA model.
    Liu CT; Neverov AA; Brown RS
    Inorg Chem; 2007 Mar; 46(5):1778-88. PubMed ID: 17256929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Palladacycle-promoted solvolytic cleavage of O,O-dimethyl O-aryl phosphorothioates. Converting a phosphorane-like transition state to an observable intermediate.
    Liu CT; Neverov AA; Brown RS
    Inorg Chem; 2011 Aug; 50(16):7852-62. PubMed ID: 21744816
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic and computational study of a palladacycle-catalyzed decomposition of a series of neutral phosphorothioate triesters in methanol.
    Liu CT; Maxwell CI; Edwards DR; Neverov AA; Mosey NJ; Brown RS
    J Am Chem Soc; 2010 Nov; 132(46):16599-609. PubMed ID: 21033707
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Steric effects on the catalytic activities of zinc(II) complexes containing [12]aneN3 ligating units in the cleavage of the RNA and DNA model phosphates.
    Song Y; Zan J; Yan H; Lu ZL; Wang R
    Org Biomol Chem; 2012 Oct; 10(38):7714-20. PubMed ID: 22699360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 57.