These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 18051403)

  • 1. [Protease inhibitors].
    Hamada Y; Kiso Y
    Tanpakushitsu Kakusan Koso; 2007 Oct; 52(13 Suppl):1702-7. PubMed ID: 18051403
    [No Abstract]   [Full Text] [Related]  

  • 2. Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.
    Piazzi L; Cavalli A; Colizzi F; Belluti F; Bartolini M; Mancini F; Recanatini M; Andrisano V; Rampa A
    Bioorg Med Chem Lett; 2008 Jan; 18(1):423-6. PubMed ID: 17998161
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Drug therapy for aged patients with Alzheimer disease].
    Kudo T
    Seishin Shinkeigaku Zasshi; 2004; 106(1):62-7. PubMed ID: 15152658
    [No Abstract]   [Full Text] [Related]  

  • 4. The potential of BACE inhibitors for Alzheimer's therapy.
    Potter H; Dressler D
    Nat Biotechnol; 2000 Feb; 18(2):125-6. PubMed ID: 10657070
    [No Abstract]   [Full Text] [Related]  

  • 5. Design of potent aspartic protease inhibitors to treat various diseases.
    Nguyen JT; Hamada Y; Kimura T; Kiso Y
    Arch Pharm (Weinheim); 2008 Sep; 341(9):523-35. PubMed ID: 18763714
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors.
    Lindsley SR; Moore KP; Rajapakse HA; Selnick HG; Young MB; Zhu H; Munshi S; Kuo L; McGaughey GB; Colussi D; Crouthamel MC; Lai MT; Pietrak B; Price EA; Sankaranarayanan S; Simon AJ; Seabrook GR; Hazuda DJ; Pudvah NT; Hochman JH; Graham SL; Vacca JP; Nantermet PG
    Bioorg Med Chem Lett; 2007 Jul; 17(14):4057-61. PubMed ID: 17482814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic.
    Wångsell F; Russo F; Sävmarker J; Rosenquist A; Samuelsson B; Larhed M
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4711-4. PubMed ID: 19576765
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Progress toward a practical BACE-1 inhibitor.
    Hills ID; Vacca JP
    Curr Opin Drug Discov Devel; 2007 Jul; 10(4):383-91. PubMed ID: 17659479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Saving the mind faces high hurdles.
    Travis J
    Science; 2005 Jul; 309(5735):731. PubMed ID: 16051787
    [No Abstract]   [Full Text] [Related]  

  • 10. Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model.
    Truong AP; Tóth G; Probst GD; Sealy JM; Bowers S; Wone DW; Dressen D; Hom RK; Konradi AW; Sham HL; Wu J; Peterson BT; Ruslim L; Bova MP; Kholodenko D; Motter RN; Bard F; Santiago P; Ni H; Chian D; Soriano F; Cole T; Brigham EF; Wong K; Zmolek W; Goldbach E; Samant B; Chen L; Zhang H; Nakamura DF; Quinn KP; Yednock TA; Sauer JM
    Bioorg Med Chem Lett; 2010 Nov; 20(21):6231-6. PubMed ID: 20833041
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific enzyme identified that snips APP into beta-amyloid.
    Senior K
    Drug Discov Today; 2005 Nov; 10(21):1408. PubMed ID: 16243255
    [No Abstract]   [Full Text] [Related]  

  • 12. Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues.
    Bäck M; Nyhlén J; Kvarnström I; Appelgren S; Borkakoti N; Jansson K; Lindberg J; Nyström S; Hallberg A; Rosenquist S; Samuelsson B
    Bioorg Med Chem; 2008 Nov; 16(21):9471-86. PubMed ID: 18842420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An inflammatory drug prospect.
    De Strooper B; König G
    Nature; 2001 Nov; 414(6860):159-60. PubMed ID: 11700538
    [No Abstract]   [Full Text] [Related]  

  • 14. BACE-1 inhibitors part 2: identification of hydroxy ethylamines (HEAs) with reduced peptidic character.
    Clarke B; Demont E; Dingwall C; Dunsdon R; Faller A; Hawkins J; Hussain I; MacPherson D; Maile G; Matico R; Milner P; Mosley J; Naylor A; O'Brien A; Redshaw S; Riddell D; Rowland P; Soleil V; Smith KJ; Stanway S; Stemp G; Sweitzer S; Theobald P; Vesey D; Walter DS; Ward J; Wayne G
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1017-21. PubMed ID: 18166458
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design of potent inhibitors of human beta-secretase. Part 1.
    Freskos JN; Fobian YM; Benson TE; Bienkowski MJ; Brown DL; Emmons TL; Heintz R; Laborde A; McDonald JJ; Mischke BV; Molyneaux JM; Moon JB; Mullins PB; Bryan Prince D; Paddock DJ; Tomasselli AG; Winterrowd G
    Bioorg Med Chem Lett; 2007 Jan; 17(1):73-7. PubMed ID: 17046251
    [TBL] [Abstract][Full Text] [Related]  

  • 16. American Chemical Society 230th National Meeting. Neurological disorders.
    Ognjenovic M; Perry L
    IDrugs; 2005 Nov; 8(11):887-9. PubMed ID: 16254777
    [No Abstract]   [Full Text] [Related]  

  • 17. Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1.
    Barrow JC; Rittle KE; Ngo PL; Selnick HG; Graham SL; Pitzenberger SM; McGaughey GB; Colussi D; Lai MT; Huang Q; Tugusheva K; Espeseth AS; Simon AJ; Munshi SK; Vacca JP
    ChemMedChem; 2007 Jul; 2(7):995-9. PubMed ID: 17458843
    [No Abstract]   [Full Text] [Related]  

  • 18. Prolonged stability by cyclization: Macrocyclic phosphino dipeptide isostere inhibitors of beta-secretase (BACE1).
    Huber T; Manzenrieder F; Kuttruff CA; Dorner-Ciossek C; Kessler H
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4427-31. PubMed ID: 19523824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design of potent inhibitors of human beta-secretase. Part 2.
    Freskos JN; Fobian YM; Benson TE; Moon JB; Bienkowski MJ; Brown DL; Emmons TL; Heintz R; Laborde A; McDonald JJ; Mischke BV; Molyneaux JM; Mullins PB; Bryan Prince D; Paddock DJ; Tomasselli AG; Winterrowd G
    Bioorg Med Chem Lett; 2007 Jan; 17(1):78-81. PubMed ID: 17049233
    [TBL] [Abstract][Full Text] [Related]  

  • 20. alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors.
    Asso V; Ghilardi E; Bertini S; Digiacomo M; Granchi C; Minutolo F; Rapposelli S; Bortolato A; Moro S; Macchia M
    ChemMedChem; 2008 Oct; 3(10):1530-4. PubMed ID: 18781572
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 9.