67 related articles for article (PubMed ID: 18051440)
1. [In-vivo activation of the p53 pathway by small-molecule antagonists of MDM2].
Shinohara T; Uesugi M
Tanpakushitsu Kakusan Koso; 2007 Oct; 52(13 Suppl):1816-7. PubMed ID: 18051440
[No Abstract] [Full Text] [Related]
2. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy.
Tovar C; Rosinski J; Filipovic Z; Higgins B; Kolinsky K; Hilton H; Zhao X; Vu BT; Qing W; Packman K; Myklebost O; Heimbrook DC; Vassilev LT
Proc Natl Acad Sci U S A; 2006 Feb; 103(6):1888-93. PubMed ID: 16443686
[TBL] [Abstract][Full Text] [Related]
3. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy.
Shangary S; Wang S
Annu Rev Pharmacol Toxicol; 2009; 49():223-41. PubMed ID: 18834305
[TBL] [Abstract][Full Text] [Related]
4. Pharmacologic activation of p53 by small-molecule MDM2 antagonists.
Shen H; Maki CG
Curr Pharm Des; 2011; 17(6):560-8. PubMed ID: 21391906
[TBL] [Abstract][Full Text] [Related]
5. Cyclin-dependent kinase inhibitors sensitize tumor cells to nutlin-induced apoptosis: a potent drug combination.
Cheok CF; Dey A; Lane DP
Mol Cancer Res; 2007 Nov; 5(11):1133-45. PubMed ID: 18025259
[TBL] [Abstract][Full Text] [Related]
6. Nutlins and ionizing radiation in cancer therapy.
Impicciatore G; Sancilio S; Miscia S; Di Pietro R
Curr Pharm Des; 2010; 16(12):1427-42. PubMed ID: 20166982
[TBL] [Abstract][Full Text] [Related]
7. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.
Vassilev LT; Vu BT; Graves B; Carvajal D; Podlaski F; Filipovic Z; Kong N; Kammlott U; Lukacs C; Klein C; Fotouhi N; Liu EA
Science; 2004 Feb; 303(5659):844-8. PubMed ID: 14704432
[TBL] [Abstract][Full Text] [Related]
8. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.
Ambrosini G; Sambol EB; Carvajal D; Vassilev LT; Singer S; Schwartz GK
Oncogene; 2007 May; 26(24):3473-81. PubMed ID: 17146434
[TBL] [Abstract][Full Text] [Related]
9. Cancer research. Drug candidate bolsters cell's tumor defenses.
Marx J
Science; 2004 Jan; 303(5654):23-5. PubMed ID: 14704399
[No Abstract] [Full Text] [Related]
10. Small-molecule MDM2-p53 inhibitors: recent advances.
Zhang B; Golding BT; Hardcastle IR
Future Med Chem; 2015; 7(5):631-45. PubMed ID: 25921402
[TBL] [Abstract][Full Text] [Related]
11. Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment.
Cui Y; Guo G
Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27869779
[TBL] [Abstract][Full Text] [Related]
12. Targeted molecular therapy for neuroblastoma: the ARF/MDM2/p53 axis.
Kim E; Shohet J
J Natl Cancer Inst; 2009 Nov; 101(22):1527-9. PubMed ID: 19903809
[No Abstract] [Full Text] [Related]
13. Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma.
Van Maerken T; Speleman F; Vermeulen J; Lambertz I; De Clercq S; De Smet E; Yigit N; Coppens V; Philippé J; De Paepe A; Marine JC; Vandesompele J
Cancer Res; 2006 Oct; 66(19):9646-55. PubMed ID: 17018622
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma.
Drakos E; Thomaides A; Medeiros LJ; Li J; Leventaki V; Konopleva M; Andreeff M; Rassidakis GZ
Clin Cancer Res; 2007 Jun; 13(11):3380-7. PubMed ID: 17545546
[TBL] [Abstract][Full Text] [Related]
15. Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors.
Carvajal D; Tovar C; Yang H; Vu BT; Heimbrook DC; Vassilev LT
Cancer Res; 2005 Mar; 65(5):1918-24. PubMed ID: 15753391
[TBL] [Abstract][Full Text] [Related]
16. A novel application for murine double minute 2 antagonists: the p53 tumor suppressor network also controls angiogenesis.
Binder BR
Circ Res; 2007 Jan; 100(1):13-4. PubMed ID: 17204660
[No Abstract] [Full Text] [Related]
17. Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A.
Müller CR; Paulsen EB; Noordhuis P; Pedeutour F; Saeter G; Myklebost O
Int J Cancer; 2007 Jul; 121(1):199-205. PubMed ID: 17354236
[TBL] [Abstract][Full Text] [Related]
18. Synthetic protocol published for promising anticancer compound.
Future Med Chem; 2011 May; 3(7):779. PubMed ID: 21644822
[No Abstract] [Full Text] [Related]
19. Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.
Efeyan A; Ortega-Molina A; Velasco-Miguel S; Herranz D; Vassilev LT; Serrano M
Cancer Res; 2007 Aug; 67(15):7350-7. PubMed ID: 17671205
[TBL] [Abstract][Full Text] [Related]
20. [TP53 and RB tumor suppressor pathways collaborate in retinoblastoma genesis].
Ayrault O; Zindy F; Roussel MF
Med Sci (Paris); 2007 Apr; 23(4):356-8. PubMed ID: 17433223
[No Abstract] [Full Text] [Related]
[Next] [New Search]
