BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 18052087)

  • 1. Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.
    Joseph TB; Wang SW; Liu X; Kulkarni KH; Wang J; Xu H; Hu M
    Mol Pharm; 2007; 4(6):883-94. PubMed ID: 18052087
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones.
    Tang L; Singh R; Liu Z; Hu M
    Mol Pharm; 2009; 6(5):1466-82. PubMed ID: 19545173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities.
    Wang SW; Kulkarni KH; Tang L; Wang JR; Yin T; Daidoji T; Yokota H; Hu M
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1023-31. PubMed ID: 19264971
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Troglitazone glucuronidation in human liver and intestine microsomes: high catalytic activity of UGT1A8 and UGT1A10.
    Watanabe Y; Nakajima M; Yokoi T
    Drug Metab Dispos; 2002 Dec; 30(12):1462-9. PubMed ID: 12433820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of benzo(a)pyrene-trans-7,8-dihydrodiol glucuronidation by human tissue microsomes and overexpressed UDP-glucuronosyltransferase enzymes.
    Fang JL; Beland FA; Doerge DR; Wiener D; Guillemette C; Marques MM; Lazarus P
    Cancer Res; 2002 Apr; 62(7):1978-86. PubMed ID: 11929814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Application of ultra high-performance liquid chromatography tandem mass spectrometry to investigate the regioselective glucuronidation of icaritin in vitro.
    Rong Y; Meng Z; Li J; Zhu X; Gan H; Gu R; Wu Z; Sun W; Liu T; Zheng Y; Jin M; Peng J; Wang X; Dou G
    J Pharm Biomed Anal; 2018 May; 154():444-453. PubMed ID: 29587224
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes.
    Zhou Q; Zheng Z; Xia B; Tang L; Lv C; Liu W; Liu Z; Hu M
    Pharm Res; 2010 Aug; 27(8):1568-83. PubMed ID: 20411407
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.
    Ogura K; Ishikawa Y; Kaku T; Nishiyama T; Ohnuma T; Muro K; Hiratsuka A
    Biochem Pharmacol; 2006 Apr; 71(9):1358-69. PubMed ID: 16480962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wedelolactone metabolism in rats through regioselective glucuronidation catalyzed by uridine diphosphate-glucuronosyltransferases 1As (UGT1As).
    Li L; Huang XJ; Peng JL; Zheng MY; Zhong DF; Zhang CF; Chen XY
    Phytomedicine; 2016 Apr; 23(4):340-9. PubMed ID: 27002404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.
    Kishi N; Takasuka A; Kokawa Y; Isobe T; Taguchi M; Shigeyama M; Murata M; Suno M; Hanioka N
    Xenobiotica; 2016; 46(4):289-95. PubMed ID: 26247833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T; Yajima K; Suzuki K; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
    Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
    Shiraga T; Yajima K; Teragaki T; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
    Biol Pharm Bull; 2012; 35(3):413-21. PubMed ID: 22382330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of UDP-glucuronosyltransferase isoforms responsible for leonurine glucuronidation in human liver and intestinal microsomes.
    Tan B; Cai W; Zhang J; Zhou N; Ma G; Yang P; Zhu Q; Zhu Y
    Xenobiotica; 2014 Sep; 44(9):775-84. PubMed ID: 24635759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.
    Li T; Zheng Y; Fu F; Ji H; Chen X; Zhao Y; Zhao D; Li N; Zhang L
    Xenobiotica; 2011 Jul; 41(7):530-7. PubMed ID: 21524190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition.
    Chen J; Wang S; Jia X; Bajimaya S; Lin H; Tam VH; Hu M
    Drug Metab Dispos; 2005 Dec; 33(12):1777-84. PubMed ID: 16120792
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro characterization of the glucuronidation pathways of licochalcone A mediated by human UDP-glucuronosyltransferases.
    Xia YL; Dou TY; Lv X; Ge GB
    Xenobiotica; 2019 Jun; 49(6):671-677. PubMed ID: 30044687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucuronidation of mono(2-ethylhexyl) phthalate in humans: roles of hepatic and intestinal UDP-glucuronosyltransferases.
    Hanioka N; Kinashi Y; Tanaka-Kagawa T; Isobe T; Jinno H
    Arch Toxicol; 2017 Feb; 91(2):689-698. PubMed ID: 27071666
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.
    Tang L; Ye L; Singh R; Wu B; Lv C; Zhao J; Liu Z; Hu M
    Mol Pharm; 2010 Jun; 7(3):664-79. PubMed ID: 20297805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.