BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

598 related articles for article (PubMed ID: 18054739)

  • 1. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
    Koren S; Fantus IG
    Best Pract Res Clin Endocrinol Metab; 2007 Dec; 21(4):621-40. PubMed ID: 18054739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes.
    Kasibhatla B; Wos J; Peters KG
    Curr Opin Investig Drugs; 2007 Oct; 8(10):805-13. PubMed ID: 17907056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein tyrosine phosphatase 1B inhibitors for diabetes.
    Johnson TO; Ermolieff J; Jirousek MR
    Nat Rev Drug Discov; 2002 Sep; 1(9):696-709. PubMed ID: 12209150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control.
    Popov D
    Biochem Biophys Res Commun; 2011 Jul; 410(3):377-81. PubMed ID: 21683066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prodrug delivery of novel PTP1B inhibitors to enhance insulin signalling.
    Erbe DV; Klaman LD; Wilson DP; Wan ZK; Kirincich SJ; Will S; Xu X; Kung L; Wang S; Tam S; Lee J; Tobin JF
    Diabetes Obes Metab; 2009 Jun; 11(6):579-88. PubMed ID: 19383031
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
    Rao GS; Ramachandran MV; Bajaj JS
    J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein tyrosine phosphatases: the quest for negative regulators of insulin action.
    Asante-Appiah E; Kennedy BP
    Am J Physiol Endocrinol Metab; 2003 Apr; 284(4):E663-70. PubMed ID: 12626322
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.
    Lorenzo M; Fernández-Veledo S; Vila-Bedmar R; Garcia-Guerra L; De Alvaro C; Nieto-Vazquez I
    J Anim Sci; 2008 Apr; 86(14 Suppl):E94-104. PubMed ID: 17940160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Research progress of several protein tyrosine phosphatases in diabetes].
    Chen M; Sun JP; Liu J; Yu X
    Sheng Li Xue Bao; 2010 Apr; 62(2):179-89. PubMed ID: 20401454
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein tyrosine phosphatase 1B inhibitors for the treatment of type 2 diabetes and obesity: recent advances.
    Harley EA; Levens N
    Curr Opin Investig Drugs; 2003 Oct; 4(10):1179-89. PubMed ID: 14649209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes.
    Liu G; Trevillyan JM
    Curr Opin Investig Drugs; 2002 Nov; 3(11):1608-16. PubMed ID: 12476961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
    Zhang S; Zhang ZY
    Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PTP1B and TCPTP--nonredundant phosphatases in insulin signaling and glucose homeostasis.
    Tiganis T
    FEBS J; 2013 Jan; 280(2):445-58. PubMed ID: 22404968
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate.
    Lee H; Xie L; Luo Y; Lee SY; Lawrence DS; Wang XB; Sotgia F; Lisanti MP; Zhang ZY
    Biochemistry; 2006 Jan; 45(1):234-40. PubMed ID: 16388599
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein tyrosine phosphatase regulation in fibroblasts from patients with an insulin receptor gene mutation.
    Seki N; Yagi S; Suzuki Y; Shimada F; Taira M; Makino H; Amano K; Yagui K; Saito Y; Hashimoto N
    Horm Metab Res; 2008 Dec; 40(12):833-7. PubMed ID: 18925540
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B.
    Wu Y; Ou-Yang JP; Wu K; Wang Y; Zhou YF; Wen CY
    Acta Pharmacol Sin; 2005 Mar; 26(3):345-52. PubMed ID: 15715932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Role of protein tyrosine phosphatase 1B in the type 2 diabetes and obesity].
    Wang C; Wang L; Yang Z
    Yi Chuan; 2004 Nov; 26(6):941-6. PubMed ID: 15640130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.
    Zhang YN; Zhang W; Hong D; Shi L; Shen Q; Li JY; Li J; Hu LH
    Bioorg Med Chem; 2008 Sep; 16(18):8697-705. PubMed ID: 18707891
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B.
    Xu JQ; Shen Q; Li J; Hu LH
    Bioorg Med Chem; 2010 Jun; 18(11):3934-9. PubMed ID: 20472439
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes.
    Tobin JF; Tam S
    Curr Opin Drug Discov Devel; 2002 Jul; 5(4):500-12. PubMed ID: 12197308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.