BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 18056278)

  • 1. Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand.
    Magee WC; Aldern KA; Hostetler KY; Evans DH
    Antimicrob Agents Chemother; 2008 Feb; 52(2):586-97. PubMed ID: 18056278
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate.
    Magee WC; Hostetler KY; Evans DH
    Antimicrob Agents Chemother; 2005 Aug; 49(8):3153-62. PubMed ID: 16048917
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus.
    Chamberlain JM; Sortino K; Sethna P; Bae A; Lanier R; Bambara RA; Dewhurst S
    Antimicrob Agents Chemother; 2019 Jan; 63(1):. PubMed ID: 30397065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine.
    Ruiz J; Beadle JR; Buller RM; Schreiwer J; Prichard MN; Keith KA; Lewis KC; Hostetler KY
    Bioorg Med Chem; 2011 May; 19(9):2950-8. PubMed ID: 21493074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.
    De Clercq E; Andrei G; Balzarini J; Leyssen P; Naesens L; Neyts J; Pannecouque C; Snoeck R; Ying C; Hocková D; Holý A
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):331-41. PubMed ID: 16247948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of inhibition of adenovirus DNA replication by the acyclic nucleoside triphosphate analogue (S)-HPMPApp: influence of the adenovirus DNA binding protein.
    Mul YM; van Miltenburg RT; De Clercq E; van der Vliet PC
    Nucleic Acids Res; 1989 Nov; 17(22):8917-29. PubMed ID: 2587248
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase.
    Xiong X; Smith JL; Kim C; Huang ES; Chen MS
    Biochem Pharmacol; 1996 Jun; 51(11):1563-7. PubMed ID: 8630098
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation.
    Xiong X; Smith JL; Chen MS
    Antimicrob Agents Chemother; 1997 Mar; 41(3):594-9. PubMed ID: 9055999
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures.
    Snoeck R; Holý A; Dewolf-Peeters C; Van Den Oord J; De Clercq E; Andrei G
    Antimicrob Agents Chemother; 2002 Nov; 46(11):3356-61. PubMed ID: 12384336
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
    Zakharova VM; Serpi M; Krylov IS; Peterson LW; Breitenbach JM; Borysko KZ; Drach JC; Collins M; Hilfinger JM; Kashemirov BA; McKenna CE
    J Med Chem; 2011 Aug; 54(16):5680-93. PubMed ID: 21812420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
    Holý A; Votruba I; Merta A; Cerný J; Veselý J; Vlach J; Sedivá K; Rosenberg I; Otmar M; Hrebabecký H
    Antiviral Res; 1990 Jun; 13(6):295-311. PubMed ID: 1699493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations in the E9L polymerase gene of cidofovir-resistant vaccinia virus strain WR are associated with the drug resistance phenotype.
    Kornbluth RS; Smee DF; Sidwell RW; Snarsky V; Evans DH; Hostetler KY
    Antimicrob Agents Chemother; 2006 Dec; 50(12):4038-43. PubMed ID: 16982794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.
    Keith KA; Hitchcock MJ; Lee WA; Holý A; Kern ER
    Antimicrob Agents Chemother; 2003 Jul; 47(7):2193-8. PubMed ID: 12821467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases alpha, delta and epsilon.
    Birkus G; Rejman D; Otmar M; Votruba I; Rosenberg I; Holy A
    Antivir Chem Chemother; 2004 Jan; 15(1):23-33. PubMed ID: 15074712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 3'-to-5' exonuclease activity of vaccinia virus DNA polymerase is essential and plays a role in promoting virus genetic recombination.
    Gammon DB; Evans DH
    J Virol; 2009 May; 83(9):4236-50. PubMed ID: 19224992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemotherapy of the acquired immune deficiency syndrome (AIDS): acyclic nucleoside phosphonate analogues.
    De Clercq E
    Int J Immunopharmacol; 1991; 13 Suppl 1():91-8. PubMed ID: 1823910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.
    Julien O; Beadle JR; Magee WC; Chatterjee S; Hostetler KY; Evans DH; Sykes BD
    J Am Chem Soc; 2011 Feb; 133(7):2264-74. PubMed ID: 21280608
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alkoxyalkyl esters of (S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine are potent inhibitors of the replication of wild-type and drug-resistant human immunodeficiency virus type 1 in vitro.
    Hostetler KY; Aldern KA; Wan WB; Ciesla SL; Beadle JR
    Antimicrob Agents Chemother; 2006 Aug; 50(8):2857-9. PubMed ID: 16870786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antiviral drug susceptibility of human herpesvirus 8.
    Neyts J; De Clercq E
    Antimicrob Agents Chemother; 1997 Dec; 41(12):2754-6. PubMed ID: 9420052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cidofovir inhibits genome encapsidation and affects morphogenesis during the replication of vaccinia virus.
    Jesus DM; Costa LT; Gonçalves DL; Achete CA; Attias M; Moussatché N; Damaso CR
    J Virol; 2009 Nov; 83(22):11477-90. PubMed ID: 19726515
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.