BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 18056446)

  • 1. c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation.
    Ravitz MJ; Chen L; Lynch M; Schmidt EV
    Cancer Res; 2007 Dec; 67(23):11209-17. PubMed ID: 18056446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.
    Smith EM; Finn SG; Tee AR; Browne GJ; Proud CG
    J Biol Chem; 2005 May; 280(19):18717-27. PubMed ID: 15772076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
    Villalonga P; Fernández de Mattos S; Ridley AJ
    J Biol Chem; 2009 Dec; 284(51):35287-96. PubMed ID: 19850923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.
    Kaur S; Lal L; Sassano A; Majchrzak-Kita B; Srikanth M; Baker DP; Petroulakis E; Hay N; Sonenberg N; Fish EN; Platanias LC
    J Biol Chem; 2007 Jan; 282(3):1757-68. PubMed ID: 17114181
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
    Inoki K; Li Y; Zhu T; Wu J; Guan KL
    Nat Cell Biol; 2002 Sep; 4(9):648-57. PubMed ID: 12172553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
    Babcock JT; Nguyen HB; He Y; Hendricks JW; Wek RC; Quilliam LA
    J Biol Chem; 2013 May; 288(22):15687-98. PubMed ID: 23612979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.
    Tee AR; Fingar DC; Manning BD; Kwiatkowski DJ; Cantley LC; Blenis J
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13571-6. PubMed ID: 12271141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.
    Miloslavski R; Cohen E; Avraham A; Iluz Y; Hayouka Z; Kasir J; Mudhasani R; Jones SN; Cybulski N; Rüegg MA; Larsson O; Gandin V; Rajakumar A; Topisirovic I; Meyuhas O
    J Mol Cell Biol; 2014 Jun; 6(3):255-66. PubMed ID: 24627160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTORC2 is required for proliferation and survival of TSC2-null cells.
    Goncharova EA; Goncharov DA; Li H; Pimtong W; Lu S; Khavin I; Krymskaya VP
    Mol Cell Biol; 2011 Jun; 31(12):2484-98. PubMed ID: 21482669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-induced energy stress regulates mRNA translation and cell growth.
    Liu L; Cash TP; Jones RG; Keith B; Thompson CB; Simon MC
    Mol Cell; 2006 Feb; 21(4):521-31. PubMed ID: 16483933
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
    Lin Y; Henderson P; Pettersson S; Satsangi J; Hupp T; Stevens C
    FEBS J; 2011 Jan; 278(2):354-70. PubMed ID: 21134130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
    Lekmine F; Uddin S; Sassano A; Parmar S; Brachmann SM; Majchrzak B; Sonenberg N; Hay N; Fish EN; Platanias LC
    J Biol Chem; 2003 Jul; 278(30):27772-80. PubMed ID: 12759354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity.
    Hahn-Windgassen A; Nogueira V; Chen CC; Skeen JE; Sonenberg N; Hay N
    J Biol Chem; 2005 Sep; 280(37):32081-9. PubMed ID: 16027121
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers.
    Pourdehnad M; Truitt ML; Siddiqi IN; Ducker GS; Shokat KM; Ruggero D
    Proc Natl Acad Sci U S A; 2013 Jul; 110(29):11988-93. PubMed ID: 23803853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth.
    Gan B; Yoo Y; Guan JL
    J Biol Chem; 2006 Dec; 281(49):37321-9. PubMed ID: 17043358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
    Bommer UA; Iadevaia V; Chen J; Knoch B; Engel M; Proud CG
    Cell Signal; 2015 Aug; 27(8):1557-68. PubMed ID: 25936523
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent.
    Jaeschke A; Hartkamp J; Saitoh M; Roworth W; Nobukuni T; Hodges A; Sampson J; Thomas G; Lamb R
    J Cell Biol; 2002 Oct; 159(2):217-24. PubMed ID: 12403809
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy.
    Chen JK; Chen J; Thomas G; Kozma SC; Harris RC
    Am J Physiol Renal Physiol; 2009 Sep; 297(3):F585-93. PubMed ID: 19474189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner.
    Kubica N; Bolster DR; Farrell PA; Kimball SR; Jefferson LS
    J Biol Chem; 2005 Mar; 280(9):7570-80. PubMed ID: 15591312
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.
    Distefano G; Boca M; Rowe I; Wodarczyk C; Ma L; Piontek KB; Germino GG; Pandolfi PP; Boletta A
    Mol Cell Biol; 2009 May; 29(9):2359-71. PubMed ID: 19255143
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.