These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 18056452)

  • 1. Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts.
    Kilbey A; Blyth K; Wotton S; Terry A; Jenkins A; Bell M; Hanlon L; Cameron ER; Neil JC
    Cancer Res; 2007 Dec; 67(23):11263-71. PubMed ID: 18056452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress.
    Wolyniec K; Wotton S; Kilbey A; Jenkins A; Terry A; Peters G; Stocking C; Cameron E; Neil JC
    Oncogene; 2009 Jul; 28(27):2502-12. PubMed ID: 19448675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p21 loss cooperates with INK4 inactivation facilitating immortalization and Bcl-2-mediated anchorage-independent growth of oncogene-transduced primary mouse fibroblasts.
    Carbone CJ; GraƱa X; Reddy EP; Haines DS
    Cancer Res; 2007 May; 67(9):4130-7. PubMed ID: 17483323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oncogenic ras and p53 cooperate to induce cellular senescence.
    Ferbeyre G; de Stanchina E; Lin AW; Querido E; McCurrach ME; Hannon GJ; Lowe SW
    Mol Cell Biol; 2002 May; 22(10):3497-508. PubMed ID: 11971980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
    Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
    Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.
    Peeper DS; Shvarts A; Brummelkamp T; Douma S; Koh EY; Daley GQ; Bernards R
    Nat Cell Biol; 2002 Feb; 4(2):148-53. PubMed ID: 11812999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.
    Wotton SF; Blyth K; Kilbey A; Jenkins A; Terry A; Bernardin-Fried F; Friedman AD; Baxter EW; Neil JC; Cameron ER
    Oncogene; 2004 Jul; 23(32):5476-86. PubMed ID: 15133495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Senescence of human fibroblasts induced by oncogenic Raf.
    Zhu J; Woods D; McMahon M; Bishop JM
    Genes Dev; 1998 Oct; 12(19):2997-3007. PubMed ID: 9765202
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.
    Zaidi SK; Pande S; Pratap J; Gaur T; Grigoriu S; Ali SA; Stein JL; Lian JB; van Wijnen AJ; Stein GS
    Proc Natl Acad Sci U S A; 2007 Dec; 104(50):19861-6. PubMed ID: 18077419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases.
    Groth A; Weber JD; Willumsen BM; Sherr CJ; Roussel MF
    J Biol Chem; 2000 Sep; 275(35):27473-80. PubMed ID: 10842176
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.
    Bulavin DV; Kovalsky O; Hollander MC; Fornace AJ
    Mol Cell Biol; 2003 Jun; 23(11):3859-71. PubMed ID: 12748288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation.
    Jackstadt R; Jung P; Hermeking H
    Cell Death Dis; 2013 Aug; 4(8):e775. PubMed ID: 23949224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.
    Kortum RL; Johnson HJ; Costanzo DL; Volle DJ; Razidlo GL; Fusello AM; Shaw AS; Lewis RE
    Mol Cell Biol; 2006 Mar; 26(6):2202-14. PubMed ID: 16507997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.
    Pantoja C; Serrano M
    Oncogene; 1999 Sep; 18(35):4974-82. PubMed ID: 10490832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bcl-2 promotes premature senescence induced by oncogenic Ras.
    Tombor B; Rundell K; Oltvai ZN
    Biochem Biophys Res Commun; 2003 Apr; 303(3):800-7. PubMed ID: 12670482
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.
    Vredeveld LC; Rowland BD; Douma S; Bernards R; Peeper DS
    Carcinogenesis; 2010 Feb; 31(2):201-7. PubMed ID: 19942610
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence.
    Hong L; Lai M; Chen M; Xie C; Liao R; Kang YJ; Xiao C; Hu WY; Han J; Sun P
    Cancer Res; 2010 Nov; 70(21):8547-57. PubMed ID: 20851997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence.
    Wang W; Chen JX; Liao R; Deng Q; Zhou JJ; Huang S; Sun P
    Mol Cell Biol; 2002 May; 22(10):3389-403. PubMed ID: 11971971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
    Hay J; Gilroy K; Huser C; Kilbey A; Mcdonald A; MacCallum A; Holroyd A; Cameron E; Neil JC
    J Cell Biochem; 2019 Oct; 120(10):18332-18345. PubMed ID: 31257681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.
    Sashida G; Liu Y; Elf S; Miyata Y; Ohyashiki K; Izumi M; Menendez S; Nimer SD
    Mol Cell Biol; 2009 Jul; 29(13):3687-99. PubMed ID: 19380490
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.