BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 18056474)

  • 1. The cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates the extracellular signal regulated kinase mitogen-activated protein kinase pathway.
    Creton SK; Zhu H; Gooderham NJ
    Cancer Res; 2007 Dec; 67(23):11455-62. PubMed ID: 18056474
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A food-born heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), suppresses tumor necrosis factor-alpha expression in lipoteichoic acid-stimulated RAW 264.7 cells.
    Im J; Choi HS; Kim SK; Woo SS; Ryu YH; Kang SS; Yun CH; Han SH
    Cancer Lett; 2009 Feb; 274(1):109-17. PubMed ID: 18845389
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine.
    Venugopal M; Agarwal R; Callaway A; Schut HA; Snyderwine EG
    Biochem Biophys Res Commun; 1999 Dec; 266(1):203-7. PubMed ID: 10581190
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity.
    Lauber SN; Ali S; Gooderham NJ
    Carcinogenesis; 2004 Dec; 25(12):2509-17. PubMed ID: 15319301
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of action of the carcinogenic heterocyclic amine PhIP.
    Gooderham NJ; Creton S; Lauber SN; Zhu H
    Toxicol Lett; 2007 Feb; 168(3):269-77. PubMed ID: 17156947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells.
    Lauber SN; Gooderham NJ
    Toxicology; 2011 Jan; 279(1-3):139-45. PubMed ID: 20951759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate.
    Nakai Y; Nelson WG; De Marzo AM
    Cancer Res; 2007 Feb; 67(3):1378-84. PubMed ID: 17264317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Responses of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) in MCF-7 cells are culture condition dependent.
    Immonen E; Serpi R; Vähäkangas K; Myllynen P
    Chem Biol Interact; 2009 Nov; 182(1):73-83. PubMed ID: 19647730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) modulates lactogenic hormone-mediated differentiation and gene expression in HC11 mouse mammary epithelial cells.
    Shan L; Rouhani SA; Schut HA; Snyderwine EG
    Cell Growth Differ; 2001 Dec; 12(12):649-56. PubMed ID: 11751460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer.
    Zhu J; Chang P; Bondy ML; Sahin AA; Singletary SE; Takahashi S; Shirai T; Li D
    Cancer Epidemiol Biomarkers Prev; 2003 Sep; 12(9):830-7. PubMed ID: 14504191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R; Piperdi S; Gorlick R
    Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells.
    Zhu H; Boobis AR; Gooderham NJ
    Cancer Res; 2000 Mar; 60(5):1283-9. PubMed ID: 10728688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Dingley KH; Curtis KD; Nowell S; Felton JS; Lang NP; Turteltaub KW
    Cancer Epidemiol Biomarkers Prev; 1999 Jun; 8(6):507-12. PubMed ID: 10385140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
    Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutive activation of the 41- and 43-kDa mitogen-activated protein (MAP) kinases in the progression of prostate cancer to an androgen-independent state.
    Oka H; Chatani Y; Kohno M; Kawakita M; Ogawa O
    Int J Urol; 2005 Oct; 12(10):899-905. PubMed ID: 16323984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitory effects of soy isoflavones on rat prostate carcinogenesis induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
    Hikosaka A; Asamoto M; Hokaiwado N; Kato K; Kuzutani K; Kohri K; Shirai T
    Carcinogenesis; 2004 Mar; 25(3):381-7. PubMed ID: 14656947
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells.
    Papaioannou MD; Koufaris C; Gooderham NJ
    Toxicol Lett; 2014 Aug; 229(1):9-16. PubMed ID: 24877718
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways.
    Wang X; Clubbs EA; Bomser JA
    J Nutr Biochem; 2006 Mar; 17(3):204-10. PubMed ID: 16198100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways.
    Schäfer R; Hartig R; Sedehizade F; Welte T; Reiser G
    FEBS J; 2006 Aug; 273(16):3756-67. PubMed ID: 16911524
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.