253 related articles for article (PubMed ID: 18064302)
1. Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
Scamuffa N; Siegfried G; Bontemps Y; Ma L; Basak A; Cherel G; Calvo F; Seidah NG; Khatib AM
J Clin Invest; 2008 Jan; 118(1):352-63. PubMed ID: 18064302
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
Khatib AM; Siegfried G; Prat A; Luis J; Chrétien M; Metrakos P; Seidah NG
J Biol Chem; 2001 Aug; 276(33):30686-93. PubMed ID: 11402025
[TBL] [Abstract][Full Text] [Related]
3. Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.
Scamuffa N; Basak A; Lalou C; Wargnier A; Marcinkiewicz J; Siegfried G; Chrétien M; Calvo F; Seidah NG; Khatib AM
Gut; 2008 Nov; 57(11):1573-82. PubMed ID: 18664504
[TBL] [Abstract][Full Text] [Related]
4. Engineering of α1-antitrypsin variants with improved specificity for the proprotein convertase furin using site-directed random mutagenesis.
Hada K; Isshiki K; Matsuda S; Yuasa K; Tsuji A
Protein Eng Des Sel; 2013 Feb; 26(2):123-31. PubMed ID: 23155057
[TBL] [Abstract][Full Text] [Related]
5. Inactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1-PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDX.
Tsuji A; Hashimoto E; Ikoma T; Taniguchi T; Mori K; Nagahama M; Matsuda Y
J Biochem; 1999 Sep; 126(3):591-603. PubMed ID: 10467177
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model.
Nejjari M; Berthet V; Rigot V; Laforest S; Jacquier MF; Seidah NG; Remy L; Bruyneel E; Scoazec JY; Marvaldi J; Luis J
Am J Pathol; 2004 Jun; 164(6):1925-33. PubMed ID: 15161629
[TBL] [Abstract][Full Text] [Related]
7. TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.
Srour N; Lebel A; McMahon S; Fournier I; Fugère M; Day R; Dubois CM
FEBS Lett; 2003 Nov; 554(3):275-83. PubMed ID: 14623079
[TBL] [Abstract][Full Text] [Related]
8. Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme 4 is required for chondrogenic differentiation in ATDC5 cells.
Yuasa K; Futamatsu G; Kawano T; Muroshita M; Kageyama Y; Taichi H; Ishikawa H; Nagahama M; Matsuda Y; Tsuji A
FEBS J; 2012 Nov; 279(21):3997-4009. PubMed ID: 22925071
[TBL] [Abstract][Full Text] [Related]
9. Proprotein convertases: "master switches" in the regulation of tumor growth and progression.
Bassi DE; Fu J; Lopez de Cicco R; Klein-Szanto AJ
Mol Carcinog; 2005 Nov; 44(3):151-61. PubMed ID: 16167351
[TBL] [Abstract][Full Text] [Related]
10. Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway.
Benjannet S; Savaria D; Laslop A; Munzer JS; Chrétien M; Marcinkiewicz M; Seidah NG
J Biol Chem; 1997 Oct; 272(42):26210-8. PubMed ID: 9334189
[TBL] [Abstract][Full Text] [Related]
11. Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases.
Sfaxi F; Scamuffa N; Lalou C; Ma J; Metrakos P; Siegfried G; Ragg H; Bikfalvi A; Calvo F; Khatib AM
Oncotarget; 2014 Jun; 5(12):4195-210. PubMed ID: 24961901
[TBL] [Abstract][Full Text] [Related]
12. Engineering of alpha1-antitrypsin variants selective for subtilisin-like proprotein convertases PACE4 and PC6: importance of the P2' residue in stable complex formation of the serpin with proprotein convertase.
Tsuji A; Kanie H; Makise H; Yuasa K; Nagahama M; Matsuda Y
Protein Eng Des Sel; 2007 Apr; 20(4):163-70. PubMed ID: 17351018
[TBL] [Abstract][Full Text] [Related]
13. The proprotein convertases furin and PACE4 play a significant role in tumor progression.
Bassi DE; Mahloogi H; Klein-Szanto AJ
Mol Carcinog; 2000 Jun; 28(2):63-9. PubMed ID: 10900462
[TBL] [Abstract][Full Text] [Related]
14. Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1.
Lapierre M; Siegfried G; Scamuffa N; Bontemps Y; Calvo F; Seidah NG; Khatib AM
Cancer Res; 2007 Oct; 67(19):9030-4. PubMed ID: 17909005
[TBL] [Abstract][Full Text] [Related]
15. Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer.
Tomé M; Pappalardo A; Soulet F; López JJ; Olaizola J; Leger Y; Dubreuil M; Mouchard A; Fessart D; Delom F; Pitard V; Bechade D; Fonck M; Rosado JA; Ghiringhelli F; Déchanet-Merville J; Soubeyran I; Siegfried G; Evrard S; Khatib AM
Cancer Res; 2019 Oct; 79(19):5008-5021. PubMed ID: 31358531
[TBL] [Abstract][Full Text] [Related]
16. Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.
Bergeron E; Basak A; Decroly E; Seidah NG
Biochem J; 2003 Jul; 373(Pt 2):475-84. PubMed ID: 12691605
[TBL] [Abstract][Full Text] [Related]
17. Identification of serpin determinants of specificity and selectivity for furin inhibition through studies of α1PDX (α1-protease inhibitor Portland)-serpin B8 and furin active-site loop chimeras.
Izaguirre G; Qi L; Lima M; Olson ST
J Biol Chem; 2013 Jul; 288(30):21802-14. PubMed ID: 23744066
[TBL] [Abstract][Full Text] [Related]
18. Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.
Kim W; Zekas E; Lodge R; Susan-Resiga D; Marcinkiewicz E; Essalmani R; Mihara K; Ramachandran R; Asahchop E; Gelman B; Cohen ÉA; Power C; Hollenberg MD; Seidah NG
Mol Cell Biol; 2015 Nov; 35(21):3684-700. PubMed ID: 26283733
[TBL] [Abstract][Full Text] [Related]
19. Prodomain of the proprotein convertase subtilisin/kexin Furin (ppFurin) protects from tumor progression and metastasis.
Scamuffa N; Sfaxi F; Ma J; Lalou C; Seidah N; Calvo F; Khatib AM
Carcinogenesis; 2014 Mar; 35(3):528-36. PubMed ID: 24127186
[TBL] [Abstract][Full Text] [Related]
20. Characterization and expression of proprotein convertases in CHO cells: Efficient proteolytic maturation of human bone morphogenetic protein-7.
Sathyamurthy M; Kim CL; Bang YL; Kim YS; Jang JW; Lee GM
Biotechnol Bioeng; 2015 Mar; 112(3):560-8. PubMed ID: 25219685
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]