180 related articles for article (PubMed ID: 18065492)
1. The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent.
Vannini N; Lorusso G; Cammarota R; Barberis M; Noonan DM; Sporn MB; Albini A
Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3139-46. PubMed ID: 18065492
[TBL] [Abstract][Full Text] [Related]
2. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
Deeb D; Gao X; Jiang H; Dulchavsky SA; Gautam SC
Prostate; 2009 Jun; 69(8):851-60. PubMed ID: 19189297
[TBL] [Abstract][Full Text] [Related]
3. The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.
Tran TA; McCoy MK; Sporn MB; Tansey MG
J Neuroinflammation; 2008 May; 5():14. PubMed ID: 18474101
[TBL] [Abstract][Full Text] [Related]
4. Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
Wang YY; Zhang CY; Ma YQ; He ZX; Zhe H; Zhou SF
Drug Des Devel Ther; 2015; 9():3163-78. PubMed ID: 26124639
[TBL] [Abstract][Full Text] [Related]
5. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
[TBL] [Abstract][Full Text] [Related]
6. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
Deeb D; Gao X; Dulchavsky SA; Gautam SC
J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
[TBL] [Abstract][Full Text] [Related]
7. Anti-angiogenic activity of a novel class of chemopreventive compounds: oleanic acid terpenoids.
Sogno I; Vannini N; Lorusso G; Cammarota R; Noonan DM; Generoso L; Sporn MB; Albini A
Recent Results Cancer Res; 2009; 181():209-12. PubMed ID: 19213570
[TBL] [Abstract][Full Text] [Related]
8. Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
To C; Ringelberg CS; Royce DB; Williams CR; Risingsong R; Sporn MB; Liby KT
Carcinogenesis; 2015 Jul; 36(7):769-81. PubMed ID: 25939751
[TBL] [Abstract][Full Text] [Related]
9. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
[TBL] [Abstract][Full Text] [Related]
10. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
[TBL] [Abstract][Full Text] [Related]
11. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
Wang YY; Yang YX; Zhao R; Pan ST; Zhe H; He ZX; Duan W; Zhang X; Yang T; Qiu JX; Zhou SF
Drug Des Devel Ther; 2015; 9():993-1026. PubMed ID: 25733817
[TBL] [Abstract][Full Text] [Related]
12. Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.
Wang YY; Yang YX; Zhe H; He ZX; Zhou SF
Drug Des Devel Ther; 2014; 8():2075-88. PubMed ID: 25364233
[TBL] [Abstract][Full Text] [Related]
13. The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.
Ling X; Konopleva M; Zeng Z; Ruvolo V; Stephens LC; Schober W; McQueen T; Dietrich M; Madden TL; Andreeff M
Cancer Res; 2007 May; 67(9):4210-8. PubMed ID: 17483332
[TBL] [Abstract][Full Text] [Related]
14. Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a.
Jutooru I; Chadalapaka G; Abdelrahim M; Basha MR; Samudio I; Konopleva M; Andreeff M; Safe S
Mol Pharmacol; 2010 Aug; 78(2):226-36. PubMed ID: 20488920
[TBL] [Abstract][Full Text] [Related]
15. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
[TBL] [Abstract][Full Text] [Related]
16. Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.
Liu Y; Gao X; Deeb D; Gautam SC
Biochem Biophys Res Commun; 2012 Jan; 417(1):570-5. PubMed ID: 22177954
[TBL] [Abstract][Full Text] [Related]
17. The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic-acid methyl ester has potent anti-diabetic effects in diet-induced diabetic mice and Lepr(db/db) mice.
Saha PK; Reddy VT; Konopleva M; Andreeff M; Chan L
J Biol Chem; 2010 Dec; 285(52):40581-92. PubMed ID: 20956520
[TBL] [Abstract][Full Text] [Related]
18. Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Liby K; Risingsong R; Royce DB; Williams CR; Yore MM; Honda T; Gribble GW; Lamph WW; Vannini N; Sogno I; Albini A; Sporn MB
Clin Cancer Res; 2008 Jul; 14(14):4556-63. PubMed ID: 18628471
[TBL] [Abstract][Full Text] [Related]
19. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
Gao X; Liu Y; Deeb D; Liu P; Liu A; Arbab AS; Gautam SC
Anticancer Res; 2013 Jan; 33(1):215-21. PubMed ID: 23267148
[TBL] [Abstract][Full Text] [Related]
20. CDDO-Me Attenuates Vasogenic Edema and Astroglial Death by Regulating NF-κB p65 Phosphorylations and Nrf2 Expression Following Status Epilepticus.
Kim MJ; Park H; Choi SH; Kong MJ; Kim JE; Kang TC
Int J Mol Sci; 2019 Sep; 20(19):. PubMed ID: 31574956
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
