BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 18066549)

  • 1. Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells.
    Adler V; Bowne W; Kamran I; Michl J; Friedman FK; Chin E; Zenilman M; Pincus MR
    Cancer Chemother Pharmacol; 2008 Aug; 62(3):491-8. PubMed ID: 18066549
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Peptides designed from molecular modeling studies of the ras-p21 protein induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth.
    Kanovsky M; Michl J; Botzolaki G; Morin J; Kovac C; Chung DL; Chie L; Friedman FK; Pincus MR
    Cancer Chemother Pharmacol; 2003 Sep; 52(3):202-8. PubMed ID: 12783204
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase.
    Adler V; Bowne W; Michl J; Sookraj KA; Ikram K; Pestka S; Izotova L; Zenilman M; Friedman FK; Qu Y; Pincus MR
    Ann Clin Lab Sci; 2008; 38(1):47-56. PubMed ID: 18316782
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A protein kinase C inhibitor induces phenotypic reversion of ras-transformed pancreatic cancer cells and cooperatively blocks tumor cell proliferation with an anti- ras peptide.
    Way D; Smith S; Sivendran S; Chie L; Kanovsky M; Brandt-Rauf PW; Chung DL; Michl J; Pincus MR
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):429-37. PubMed ID: 12107546
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effector peptides from glutathione-S-transferase-pi affect the activation of jun by jun-N-terminal kinase.
    Adler V; Pincus MR
    Ann Clin Lab Sci; 2004; 34(1):35-46. PubMed ID: 15038666
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
    Adler V; Qu Y; Smith SJ; Izotova L; Pestka S; Kung HF; Lin M; Friedman FK; Chie L; Chung D; Boutjdir M; Pincus MR
    Biochemistry; 2005 Aug; 44(32):10784-95. PubMed ID: 16086581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differences in patterns of activation of MAP kinases induced by oncogenic ras-p21 and insulin in oocytes.
    Ranginwale M; Smith S; Flom J; Chie L; Kanovsky M; Chung D; Friedman FK; Robinson RC; Brandt-Rauf PW; Yamaizumi Z; Michl J; Pincus MR
    Exp Cell Res; 2001 Sep; 269(1):162-9. PubMed ID: 11525649
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A peptide from a ras effector-domain blocks ras-dependent cardiac hypertrophy in myocytes.
    Deng L; Boujdir M; Tremontano A; Pincus MR; El-Sherif N
    Ann Clin Lab Sci; 2009; 39(4):351-60. PubMed ID: 19880762
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reversal of the transformed phenotype and inhibition of peptidylglycine alpha-monooxygenase in Ras-transformed cells by 4-phenyl-3-butenoic acid.
    Sunman JA; Foster MS; Folse SL; May SW; Matesic DF
    Mol Carcinog; 2004 Dec; 41(4):231-46. PubMed ID: 15468302
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents.
    Amar S; Glozman A; Chung D; Adler V; Ronai Z; Friedman FK; Robinson R; Brandt-Rauf P; Yamaizumi Z; Pincus MR
    Cancer Chemother Pharmacol; 1997; 41(1):79-85. PubMed ID: 9443618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells.
    Bowne WB; Sookraj KA; Vishnevetsky M; Adler V; Sarafraz-Yazdi E; Lou S; Koenke J; Shteyler V; Ikram K; Harding M; Bluth MH; Ng M; Brandt-Rauf PW; Hannan R; Bradu S; Zenilman ME; Michl J; Pincus MR
    Ann Surg Oncol; 2008 Dec; 15(12):3588-600. PubMed ID: 18931881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of apicidin, a histone deacetylase inhibitor, on the regulation of apoptosis in H-ras-transformed breast epithelial cells.
    Park H; Im JY; Kim J; Choi WS; Kim HS
    Int J Mol Med; 2008 Mar; 21(3):325-33. PubMed ID: 18288380
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-cancer peptides from ras-p21 and p53 proteins.
    Pincus MR; Fenelus M; Sarafraz-Yazdi E; Adler V; Bowne W; Michl J
    Curr Pharm Des; 2011; 17(25):2677-98. PubMed ID: 21728981
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W
    J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel peptides from the RAS-p21 and p53 proteins for the treatment of cancer.
    Bowne WB; Michl J; Bluth MH; Zenilman ME; Pincus MR
    Cancer Ther; 2007; 5B():331-344. PubMed ID: 18007958
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of Ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with Ki-ras mutation but not those without Ki-ras mutation.
    Aoki K; Yoshida T; Matsumoto N; Ide H; Sugimura T; Terada M
    Mol Carcinog; 1997 Oct; 20(2):251-8. PubMed ID: 9364215
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins.
    Pincus MR
    Front Biosci; 2004 Sep; 9():3486-509. PubMed ID: 15353372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells.
    Yu JH; Wang HJ; Li XR; Tashiro S; Onodera S; Ikejima T
    Acta Pharmacol Sin; 2008 Sep; 29(9):1069-76. PubMed ID: 18718176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of reactive oxygen species/c-Jun NH(2)-terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells.
    Kuo PL; Chen CY; Tzeng TF; Lin CC; Hsu YL
    Toxicol Appl Pharmacol; 2008 Jun; 229(2):215-26. PubMed ID: 18374381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells.
    Michod D; Yang JY; Chen J; Bonny C; Widmann C
    Oncogene; 2004 Nov; 23(55):8971-8. PubMed ID: 15467750
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.