BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 18066826)

  • 1. Sequence-specific recognition of double-stranded DNA by synthetic minor groove binder conjugates. toward the construction of artificial site-specific deoxyribonucleases.
    Boutorine AS; Halby L; Simon P; Perrouault L; Giovannangeli C; Gursky GV; Surovaya AN; Grokhovsky SL; Ryabinin VA; Sinyakov AN
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1559-63. PubMed ID: 18066826
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Head-to-head bis-hairpin polyamide minor groove binders and their conjugates with triplex-forming oligonucleotides: studies of interaction with target double-stranded DNA.
    Halby L; Ryabinin VA; Sinyakov AN; Novopashina DS; Venyaminova AG; Grokhovsky SL; Surovaya AN; Gursky GV; Boutorine AS
    J Biomol Struct Dyn; 2007 Aug; 25(1):61-76. PubMed ID: 17676939
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequence-specific conjugates of oligo(2'-O-methylribonucleotides) and hairpin oligocarboxamide minor-groove binders: design, synthesis, and binding studies with double-stranded DNA.
    Novopashina DS; Sinyakov AN; Ryabinin VA; Venyaminova AG; Halby L; Sun JS; Boutorine AS
    Chem Biodivers; 2005 Jul; 2(7):936-52. PubMed ID: 17193185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
    O'Hare CC; Uthe P; Mackay H; Blackmon K; Jones J; Brown T; Nguyen B; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2007 Oct; 46(42):11661-70. PubMed ID: 17910471
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.
    Ryabinin VA; Boutorine AS; Hélène C; Pyshnyi DV; Sinyakov AN
    Nucleosides Nucleotides Nucleic Acids; 2004 May; 23(5):789-803. PubMed ID: 15281367
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies of sequence-specific recognition and interaction of bishairpin polyamide minor groove binders with target DNA duplexes.
    Boutorine AS; Buchmann W; Halby L; De Pauw E
    Nucleic Acids Symp Ser (Oxf); 2008; (52):105-6. PubMed ID: 18776275
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L; Mackay H; Brown T; Nguyen B; Kluza J; Wilson WD; Lee M; Hartley JA
    Biochemistry; 2009 Jun; 48(24):5679-88. PubMed ID: 19419200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
    Pilch DS; Poklar N; Baird EE; Dervan PB; Breslauer KJ
    Biochemistry; 1999 Feb; 38(7):2143-51. PubMed ID: 10026298
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex.
    Ryabinin VA; Boutorine AS; Hélène C; Denisov AY; Pyshnyi DV; Sinyakov AN
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(6-7):953-68. PubMed ID: 15560087
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequence selective recognition in the minor groove of dsDNA by pyrrole, imidazole-substituted bis-benzimidazole conjugates.
    Reddy PM; Jindra PT; Satz AL; Bruice TC
    J Am Chem Soc; 2003 Jul; 125(26):7843-8. PubMed ID: 12823002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine.
    Nguyen B; Tardy C; Bailly C; Colson P; Houssier C; Kumar A; Boykin DW; Wilson WD
    Biopolymers; 2002 Apr; 63(5):281-97. PubMed ID: 11877739
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA alkylation by pyrrole-imidazole seco-CBI conjugates with an indole linker: sequence-specific DNA alkylation with 10-base-pair recognition through heterodimer formation.
    Minoshima M; Bando T; Sasaki S; Shinohara K; Shimizu T; Fujimoto J; Sugiyama H
    J Am Chem Soc; 2007 May; 129(17):5384-90. PubMed ID: 17425308
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.
    Bando T; Sugiyama H
    Acc Chem Res; 2006 Dec; 39(12):935-44. PubMed ID: 17176032
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conjugates of oligo(2'-O-methylribonucleotides) with minor groove binders as new sequence-specific agents recognizing both grooves of double-stranded DNA.
    Novopashina D; Sinyakov A; Ryabinin V; Venyaminova A; Boutorine A
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1179-82. PubMed ID: 14565374
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular determinants for DNA minor groove recognition: design of a bis-guanidinium derivative of ethidium that is highly selective for AT-rich DNA sequences.
    Bailly C; Arafa RK; Tanious FA; Laine W; Tardy C; Lansiaux A; Colson P; Boykin DW; Wilson WD
    Biochemistry; 2005 Feb; 44(6):1941-52. PubMed ID: 15697219
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates.
    Bando T; Narita A; Saito I; Sugiyama H
    J Am Chem Soc; 2003 Mar; 125(12):3471-85. PubMed ID: 12643709
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA-stacking interactions determine the sequence specificity of the deoxyribonuclease activity of 1,10-phenanthroline-copper ion.
    Schaeffer F; Rimsky S; Spassky A
    J Mol Biol; 1996 Jul; 260(4):523-39. PubMed ID: 8759318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Artificial nucleases: specific cleavage of the double helix of DNA by oligonucleotides linked to copper-phenanthroline complex].
    François JC; Saison-Behmoaras T; Chassignol M; Thuong NT; Hélène C
    C R Acad Sci III; 1988; 307(20):849-54. PubMed ID: 2854494
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole-imidazole polyamides.
    Price CA; Lingerfelt BM; Handl HL; Kiakos K; Hartley JA; Lee M
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3151-6. PubMed ID: 15876536
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.