223 related articles for article (PubMed ID: 18066858)
1. Synthesis and anti-HIV activity of cyclic pyrimidine phosphonomethoxy nucleosides and their prodrugs: a comparison of phosphonates and corresponding nucleosides.
Mackman RL; Zhang L; Prasad V; Boojamra CG; Chen J; Douglas J; Grant D; Laflamme G; Hui H; Kim CU; Parrish J; Stoycheva AD; Swaminathan S; Wang K; Cihlar T
Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):573-7. PubMed ID: 18066858
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
Mackman RL; Zhang L; Prasad V; Boojamra CG; Douglas J; Grant D; Hui H; Kim CU; Laflamme G; Parrish J; Stoycheva AD; Swaminathan S; Wang K; Cihlar T
Bioorg Med Chem; 2007 Aug; 15(16):5519-28. PubMed ID: 17562366
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.
Boojamra CG; Parrish JP; Sperandio D; Gao Y; Petrakovsky OV; Lee SK; Markevitch DY; Vela JE; Laflamme G; Chen JM; Ray AS; Barron AC; Sparacino ML; Desai MC; Kim CU; Cihlar T; Mackman RL
Bioorg Med Chem; 2009 Feb; 17(4):1739-46. PubMed ID: 19179082
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.
Mackman RL; Boojamra CG; Prasad V; Zhang L; Lin KY; Petrakovsky O; Babusis D; Chen J; Douglas J; Grant D; Hui HC; Kim CU; Markevitch DY; Vela J; Ray A; Cihlar T
Bioorg Med Chem Lett; 2007 Dec; 17(24):6785-9. PubMed ID: 18029175
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.
Boojamra CG; Mackman RL; Markevitch DY; Prasad V; Ray AS; Douglas J; Grant D; Kim CU; Cihlar T
Bioorg Med Chem Lett; 2008 Feb; 18(3):1120-3. PubMed ID: 18164198
[TBL] [Abstract][Full Text] [Related]
6. Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity.
Romanowska J; Sobkowski M; Szymańska-Michalak A; Kołodziej K; Dąbrowska A; Lipniacki A; Piasek A; Pietrusiewicz ZM; Figlerowicz M; Guranowski A; Boryski J; Stawiński J; Kraszewski A
J Med Chem; 2011 Oct; 54(19):6482-91. PubMed ID: 21834513
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and anti-HIV evaluation of new acyclic phosphonate nucleotide analogues and their bis(SATE) derivatives.
Li H; Hong JH
Nucleosides Nucleotides Nucleic Acids; 2010 Aug; 29(8):581-90. PubMed ID: 20661812
[TBL] [Abstract][Full Text] [Related]
8. A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
Jansa P; Baszczyňski O; Dračínský M; Votruba I; Zídek Z; Bahador G; Stepan G; Cihlar T; Mackman R; Holý A; Janeba Z
Eur J Med Chem; 2011 Sep; 46(9):3748-54. PubMed ID: 21664011
[TBL] [Abstract][Full Text] [Related]
9. l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.
Chong Y; Gumina G; Mathew JS; Schinazi RF; Chu CK
J Med Chem; 2003 Jul; 46(15):3245-56. PubMed ID: 12852755
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and anti-HIV-1 evaluation of phosphonates which mimic the 5'-monophosphate of 4'-branched 2',3'-didehydro-2',3'-dideoxy nucleosides.
Kubota Y; Ishizaki N; Haraguchi K; Hamasaki T; Baba M; Tanaka H
Bioorg Med Chem; 2010 Oct; 18(20):7186-92. PubMed ID: 20833550
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides.
Romeo G; Iannazzo D; Piperno A; Romeo R; Saglimbeni M; Chiacchio MA; Balestrieri E; Macchi B; Mastino A
Bioorg Med Chem; 2006 Jun; 14(11):3818-24. PubMed ID: 16480883
[TBL] [Abstract][Full Text] [Related]
12. Aryl nucleoside H-phosphonates. Part 16: synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters.
Romanowska J; Szymańska-Michalak A; Boryski J; Stawiński J; Kraszewski A; Loddo R; Sanna G; Collu G; Secci B; La Colla P
Bioorg Med Chem; 2009 May; 17(9):3489-98. PubMed ID: 19282192
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of novel SATE derivatives of acyclic isocytosine and 9-deazaadenine C-nucleosides.
Liu LJ; Hong JH
Nucleosides Nucleotides Nucleic Acids; 2010 Mar; 29(3):257-66. PubMed ID: 20408056
[TBL] [Abstract][Full Text] [Related]
14. 2'-Fluoro-4'-thio-2',3'-unsaturated nucleosides: anti-HIV activity, resistance profile, and molecular modeling studies.
Chong Y; Choo H; Schinazi RF; Chu CK
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):611-5. PubMed ID: 14565238
[TBL] [Abstract][Full Text] [Related]
15. In vitro study of resistance-associated genotypic mutations to nucleoside analogs.
Gashnikova N; Plyasunova O; Kiseleva Y; Fedyuk N; Pokrovsky A
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):991-4. PubMed ID: 14565328
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anti-retroviral activity of O,O'-bis(3'-azido-2',3'-dideoxythymidin-5'-yl) phosphoramidate derivatives.
Kers I; Stawiński J; Girardet JL; Imbach JL; Périgaud C; Gosselin G; Aubertin AM
Nucleosides Nucleotides; 1999 Oct; 18(10):2317-25. PubMed ID: 10616733
[TBL] [Abstract][Full Text] [Related]
17. Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides.
Shirokova EA; Jasko MV; Khandazhinskaya AL; Ivanov AV; Yanvarev DV; Skoblov YS; Mitkevich VA; Bocharov EV; Pronyaeva TR; Fedyuk NV; Kukhanova MK; Pokrovsky AG
J Med Chem; 2004 Jul; 47(14):3606-14. PubMed ID: 15214788
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Mackman RL; Lin KY; Boojamra CG; Hui H; Douglas J; Grant D; Petrakovsky O; Prasad V; Ray AS; Cihlar T
Bioorg Med Chem Lett; 2008 Feb; 18(3):1116-9. PubMed ID: 18082402
[TBL] [Abstract][Full Text] [Related]
19. 5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.
Hocková D; Holý A; Masojídková M; Andrei G; Snoeck R; De Clercq E; Balzarini J
J Med Chem; 2003 Nov; 46(23):5064-73. PubMed ID: 14584956
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and anti-HIV activity of [ddN]-[ddN] dimers and benzimidazole nucleoside dimers.
Li GR; Liu J; Pan Q; Song ZB; Luo FL; Wang SR; Zhang XL; Zhou X
Chem Biodivers; 2009 Dec; 6(12):2200-8. PubMed ID: 20020452
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
