302 related articles for article (PubMed ID: 18071026)
1. Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets.
Shu L; Sauter NS; Schulthess FT; Matveyenko AV; Oberholzer J; Maedler K
Diabetes; 2008 Mar; 57(3):645-53. PubMed ID: 18071026
[TBL] [Abstract][Full Text] [Related]
2. Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function.
Shu L; Matveyenko AV; Kerr-Conte J; Cho JH; McIntosh CH; Maedler K
Hum Mol Genet; 2009 Jul; 18(13):2388-99. PubMed ID: 19386626
[TBL] [Abstract][Full Text] [Related]
3. TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells.
Loder MK; da Silva Xavier G; McDonald A; Rutter GA
Biochem Soc Trans; 2008 Jun; 36(Pt 3):357-9. PubMed ID: 18481957
[TBL] [Abstract][Full Text] [Related]
4. TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.
Takamoto I; Kubota N; Nakaya K; Kumagai K; Hashimoto S; Kubota T; Inoue M; Kajiwara E; Katsuyama H; Obata A; Sakurai Y; Iwamoto M; Kitamura T; Ueki K; Kadowaki T
Diabetologia; 2014 Mar; 57(3):542-53. PubMed ID: 24317852
[TBL] [Abstract][Full Text] [Related]
5. TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.
da Silva Xavier G; Loder MK; McDonald A; Tarasov AI; Carzaniga R; Kronenberger K; Barg S; Rutter GA
Diabetes; 2009 Apr; 58(4):894-905. PubMed ID: 19168596
[TBL] [Abstract][Full Text] [Related]
6. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
Lyssenko V; Lupi R; Marchetti P; Del Guerra S; Orho-Melander M; Almgren P; Sjögren M; Ling C; Eriksson KF; Lethagen AL; Mancarella R; Berglund G; Tuomi T; Nilsson P; Del Prato S; Groop L
J Clin Invest; 2007 Aug; 117(8):2155-63. PubMed ID: 17671651
[TBL] [Abstract][Full Text] [Related]
7. Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.
da Silva Xavier G; Mondragon A; Sun G; Chen L; McGinty JA; French PM; Rutter GA
Diabetologia; 2012 Oct; 55(10):2667-2676. PubMed ID: 22717537
[TBL] [Abstract][Full Text] [Related]
8. Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
Zhou Y; Zhang E; Berggreen C; Jing X; Osmark P; Lang S; Cilio CM; Göransson O; Groop L; Renström E; Hansson O
Hum Mol Genet; 2012 Jan; 21(1):196-207. PubMed ID: 21965303
[TBL] [Abstract][Full Text] [Related]
9. Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas.
Columbus J; Chiang Y; Shao W; Zhang N; Wang D; Gaisano HY; Wang Q; Irwin DM; Jin T
J Endocrinol; 2010 Oct; 207(1):77-86. PubMed ID: 20675304
[TBL] [Abstract][Full Text] [Related]
10. Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.
Schäfer SA; Tschritter O; Machicao F; Thamer C; Stefan N; Gallwitz B; Holst JJ; Dekker JM; 't Hart LM; Nijpels G; van Haeften TW; Häring HU; Fritsche A
Diabetologia; 2007 Dec; 50(12):2443-50. PubMed ID: 17661009
[TBL] [Abstract][Full Text] [Related]
11. Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner.
Sakhneny L; Rachi E; Epshtein A; Guez HC; Wald-Altman S; Lisnyansky M; Khalifa-Malka L; Hazan A; Baer D; Priel A; Weil M; Landsman L
Diabetes; 2018 Mar; 67(3):437-447. PubMed ID: 29246974
[TBL] [Abstract][Full Text] [Related]
12. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
Chen J; Saxena G; Mungrue IN; Lusis AJ; Shalev A
Diabetes; 2008 Apr; 57(4):938-44. PubMed ID: 18171713
[TBL] [Abstract][Full Text] [Related]
13. Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.
Seshadri N; Jonasson ME; Hunt KL; Xiang B; Cooper S; Wheeler MB; Dolinsky VW; Doucette CA
Mol Metab; 2017 Jul; 6(7):760-769. PubMed ID: 28702331
[TBL] [Abstract][Full Text] [Related]
14. The LIM homeodomain protein ISL1 mediates the function of TCF7L2 in pancreatic beta cells.
Shao W; Szeto V; Song Z; Tian L; Feng ZP; Nostro MC; Jin T
J Mol Endocrinol; 2018 Jul; 61(1):1-12. PubMed ID: 29678908
[TBL] [Abstract][Full Text] [Related]
15. TCF7L2 splice variants have distinct effects on beta-cell turnover and function.
Le Bacquer O; Shu L; Marchand M; Neve B; Paroni F; Kerr Conte J; Pattou F; Froguel P; Maedler K
Hum Mol Genet; 2011 May; 20(10):1906-15. PubMed ID: 21357677
[TBL] [Abstract][Full Text] [Related]
16. Wnt signaling in pancreatic islets.
Liu Z; Habener JF
Adv Exp Med Biol; 2010; 654():391-419. PubMed ID: 20217507
[TBL] [Abstract][Full Text] [Related]
17. TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals.
Le Bacquer O; Kerr-Conte J; Gargani S; Delalleau N; Huyvaert M; Gmyr V; Froguel P; Neve B; Pattou F
Diabetologia; 2012 Oct; 55(10):2677-2681. PubMed ID: 22911383
[TBL] [Abstract][Full Text] [Related]
18. Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice.
Nguyen-Tu MS; Martinez-Sanchez A; Leclerc I; Rutter GA; da Silva Xavier G
Diabetologia; 2021 Jan; 64(1):129-141. PubMed ID: 33068125
[TBL] [Abstract][Full Text] [Related]
19. Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2).
Liu Z; Habener JF
Diabetologia; 2009 Aug; 52(8):1589-98. PubMed ID: 19468708
[TBL] [Abstract][Full Text] [Related]
20. Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Mitchell RK; Mondragon A; Chen L; Mcginty JA; French PM; Ferrer J; Thorens B; Hodson DJ; Rutter GA; Da Silva Xavier G
Hum Mol Genet; 2015 Mar; 24(5):1390-9. PubMed ID: 25355422
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
