186 related articles for article (PubMed ID: 18071310)
1. Hsp90-inhibitor geldanamycin abrogates G2 arrest in p53-negative leukemia cell lines through the depletion of Chk1.
Sugimoto K; Sasaki M; Isobe Y; Tsutsui M; Suto H; Ando J; Tamayose K; Ando M; Oshimi K
Oncogene; 2008 May; 27(22):3091-101. PubMed ID: 18071310
[TBL] [Abstract][Full Text] [Related]
2. 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
Tse AN; Sheikh TN; Alan H; Chou TC; Schwartz GK
Mol Pharmacol; 2009 Jan; 75(1):124-33. PubMed ID: 18820127
[TBL] [Abstract][Full Text] [Related]
3. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
[TBL] [Abstract][Full Text] [Related]
4. The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.
Georgakis GV; Li Y; Rassidakis GZ; Medeiros LJ; Younes A
Exp Hematol; 2006 Dec; 34(12):1670-9. PubMed ID: 17157164
[TBL] [Abstract][Full Text] [Related]
5. Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
Robles AI; Wright MH; Gandhi B; Feis SS; Hanigan CL; Wiestner A; Varticovski L
Clin Cancer Res; 2006 Nov; 12(21):6547-56. PubMed ID: 17085670
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stress.
Furusawa Y; Iizumi T; Fujiwara Y; Zhao QL; Tabuchi Y; Nomura T; Kondo T
Apoptosis; 2012 Jan; 17(1):102-12. PubMed ID: 22080164
[TBL] [Abstract][Full Text] [Related]
7. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
Schwock J; Pham NA; Cao MP; Hedley DW
Cancer Chemother Pharmacol; 2008 Apr; 61(4):669-81. PubMed ID: 17579866
[TBL] [Abstract][Full Text] [Related]
8. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
[TBL] [Abstract][Full Text] [Related]
9. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
Liu X; Guo Y; Li Y; Jiang Y; Chubb S; Azuma A; Huang P; Matsuda A; Hittelman W; Plunkett W
Cancer Res; 2005 Aug; 65(15):6874-81. PubMed ID: 16061671
[TBL] [Abstract][Full Text] [Related]
10. p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest.
Wang XQ; Stanbridge EJ; Lao X; Cai Q; Fan ST; Redpath JL
Radiat Res; 2007 Dec; 168(6):706-15. PubMed ID: 18088187
[TBL] [Abstract][Full Text] [Related]
11. Sequential activation and inactivation of G2 checkpoints for selective killing of p53-deficient cells by microtubule-active drugs.
Blagosklonny MV
Oncogene; 2002 Sep; 21(41):6249-54. PubMed ID: 12214265
[TBL] [Abstract][Full Text] [Related]
12. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
Pan Y; Ren KH; He HW; Shao RG
Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
[TBL] [Abstract][Full Text] [Related]
13. Synergism between etoposide and 17-AAG in leukemia cells: critical roles for Hsp90, FLT3, topoisomerase II, Chk1, and Rad51.
Yao Q; Weigel B; Kersey J
Clin Cancer Res; 2007 Mar; 13(5):1591-600. PubMed ID: 17332306
[TBL] [Abstract][Full Text] [Related]
14. Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents.
Luo Y; Rockow-Magnone SK; Joseph MK; Bradner J; Butler CC; Tahir SK; Han EK; Ng SC; Severin JM; Gubbins EJ; Reilly RM; Rueter A; Simmer RL; Holzman TF; Giranda VL
Anticancer Res; 2001; 21(1A):23-8. PubMed ID: 11299740
[TBL] [Abstract][Full Text] [Related]
15. Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest.
Levesque AA; Fanous AA; Poh A; Eastman A
Mol Cancer Ther; 2008 Feb; 7(2):252-62. PubMed ID: 18281511
[TBL] [Abstract][Full Text] [Related]
16. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
Chen Z; Xiao Z; Gu WZ; Xue J; Bui MH; Kovar P; Li G; Wang G; Tao ZF; Tong Y; Lin NH; Sham HL; Wang JY; Sowin TJ; Rosenberg SH; Zhang H
Int J Cancer; 2006 Dec; 119(12):2784-94. PubMed ID: 17019715
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of geldanamycin analogs against human cancer cells.
Li YP; Chen JJ; Shen JJ; Cui J; Wu LZ; Wang Z; Li ZR
Cancer Chemother Pharmacol; 2015 Apr; 75(4):773-82. PubMed ID: 25681003
[TBL] [Abstract][Full Text] [Related]
18. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
Yu Q; La Rose J; Zhang H; Takemura H; Kohn KW; Pommier Y
Cancer Res; 2002 Oct; 62(20):5743-8. PubMed ID: 12384533
[TBL] [Abstract][Full Text] [Related]
19. Mangiferin induces cell cycle arrest at G2/M phase through ATR-Chk1 pathway in HL-60 leukemia cells.
Peng ZG; Yao YB; Yang J; Tang YL; Huang X
Genet Mol Res; 2015 May; 14(2):4989-5002. PubMed ID: 25966274
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
Srethapakdi M; Liu F; Tavorath R; Rosen N
Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
