186 related articles for article (PubMed ID: 18071310)
21. The Chk1-Cdc25C regulation is involved in sensitizing A253 cells to a novel topoisomerase I inhibitor BNP1350 by bax gene transfer.
Yin M; Hapke G; Guo B; Azrak RG; Frank C; Rustum YM
Oncogene; 2001 Aug; 20(38):5249-57. PubMed ID: 11536038
[TBL] [Abstract][Full Text] [Related]
22. Geldanamycin induces G2 arrest in U87MG glioblastoma cells through downregulation of Cdc2 and cyclin B1.
Nomura N; Nomura M; Newcomb EW; Zagzag D
Biochem Pharmacol; 2007 May; 73(10):1528-36. PubMed ID: 17324379
[TBL] [Abstract][Full Text] [Related]
23. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
[TBL] [Abstract][Full Text] [Related]
24. The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog.
He G; Kuang J; Khokhar AR; Siddik ZH
Gynecol Oncol; 2011 Aug; 122(2):402-9. PubMed ID: 21592546
[TBL] [Abstract][Full Text] [Related]
25. Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells.
Moran DM; Gawlak G; Jayaprakash MS; Mayar S; Maki CG
Oncogene; 2008 Sep; 27(42):5567-77. PubMed ID: 18504430
[TBL] [Abstract][Full Text] [Related]
26. Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair.
Han FF; Li L; Shang BY; Shao RG; Zhen YS
Asian Pac J Cancer Prev; 2014; 15(17):7043-8. PubMed ID: 25227788
[TBL] [Abstract][Full Text] [Related]
27. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level.
Yu W; Rao Q; Wang M; Tian Z; Lin D; Liu X; Wang J
Leuk Res; 2006 May; 30(5):575-82. PubMed ID: 16213582
[TBL] [Abstract][Full Text] [Related]
28. Inhibition of cell death and induction of G2 arrest accumulation in human ovarian clear cells by HNF-1β transcription factor: chemosensitivity is regulated by checkpoint kinase CHK1.
Shigetomi H; Sudo T; Shimada K; Uekuri C; Tsuji Y; Kanayama S; Naruse K; Yamada Y; Konishi N; Kobayashi H
Int J Gynecol Cancer; 2014 Jun; 24(5):838-43. PubMed ID: 24804869
[TBL] [Abstract][Full Text] [Related]
29. Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.
Jin ZH; Kurosu T; Yamaguchi M; Arai A; Miura O
Oncogene; 2005 Mar; 24(12):1973-81. PubMed ID: 15674326
[TBL] [Abstract][Full Text] [Related]
30. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
Babchia N; Calipel A; Mouriaux F; Faussat AM; Mascarelli F
Invest Ophthalmol Vis Sci; 2008 Jun; 49(6):2348-56. PubMed ID: 18281615
[TBL] [Abstract][Full Text] [Related]
31. Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells.
Wang Y; Liu Q; Liu Z; Li B; Sun Z; Zhou H; Zhang X; Gong Y; Shao C
Mutat Res; 2012 Jun; 734(1-2):20-9. PubMed ID: 22561209
[TBL] [Abstract][Full Text] [Related]
32. An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage.
Jackson JR; Gilmartin A; Imburgia C; Winkler JD; Marshall LA; Roshak A
Cancer Res; 2000 Feb; 60(3):566-72. PubMed ID: 10676638
[TBL] [Abstract][Full Text] [Related]
33. Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38.
Hapke G; Yin MB; Wu J; Frank C; Rustum YM
Int J Oncol; 2002 Nov; 21(5):1059-66. PubMed ID: 12370755
[TBL] [Abstract][Full Text] [Related]
34. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.
Xiao Z; Chen Z; Gunasekera AH; Sowin TJ; Rosenberg SH; Fesik S; Zhang H
J Biol Chem; 2003 Jun; 278(24):21767-73. PubMed ID: 12676925
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells.
Koniaras K; Cuddihy AR; Christopoulos H; Hogg A; O'Connell MJ
Oncogene; 2001 Nov; 20(51):7453-63. PubMed ID: 11709716
[TBL] [Abstract][Full Text] [Related]
36. p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Fujii Y; Kato T; Kubota N; Fujimori A; Niwa O; Okayasu R
Oncol Rep; 2010 Jan; 23(1):199-203. PubMed ID: 19956882
[TBL] [Abstract][Full Text] [Related]
37. Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction.
Stingl L; Stühmer T; Chatterjee M; Jensen MR; Flentje M; Djuzenova CS
Br J Cancer; 2010 May; 102(11):1578-91. PubMed ID: 20502461
[TBL] [Abstract][Full Text] [Related]
38. Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells.
Gao Q; Huang X; Tang D; Cao Y; Chen G; Lu Y; Zhuang L; Wang S; Xu G; Zhou J; Ma D
Apoptosis; 2006 Oct; 11(10):1789-800. PubMed ID: 16927022
[TBL] [Abstract][Full Text] [Related]
39. Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells.
Schumacher JA; Crockett DK; Elenitoba-Johnson KS; Lim MS
Proteomics; 2007 Aug; 7(15):2603-16. PubMed ID: 17610208
[TBL] [Abstract][Full Text] [Related]
40. p53 down-regulates CHK1 through p21 and the retinoblastoma protein.
Gottifredi V; Karni-Schmidt O; Shieh SS; Prives C
Mol Cell Biol; 2001 Feb; 21(4):1066-76. PubMed ID: 11158294
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]