BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 18077445)

  • 1. Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1.
    Guan B; Pungaliya P; Li X; Uquillas C; Mutton LN; Rubin EH; Bieberich CJ
    J Biol Chem; 2008 Feb; 283(8):4834-40. PubMed ID: 18077445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo.
    Weger S; Hammer E; Heilbronn R
    FEBS Lett; 2005 Sep; 579(22):5007-12. PubMed ID: 16122737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proline-mediated proteasomal degradation of the prostate-specific tumor suppressor NKX3.1.
    Rao V; Guan B; Mutton LN; Bieberich CJ
    J Biol Chem; 2012 Oct; 287(43):36331-40. PubMed ID: 22910912
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53.
    Rajendra R; Malegaonkar D; Pungaliya P; Marshall H; Rasheed Z; Brownell J; Liu LF; Lutzker S; Saleem A; Rubin EH
    J Biol Chem; 2004 Aug; 279(35):36440-4. PubMed ID: 15247280
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plk1-mediated phosphorylation of Topors regulates p53 stability.
    Yang X; Li H; Zhou Z; Wang WH; Deng A; Andrisani O; Liu X
    J Biol Chem; 2009 Jul; 284(28):18588-92. PubMed ID: 19473992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene.
    Czub B; Shah AZ; Alfano G; Kruczek PM; Chakarova CF; Bhattacharya SS
    PLoS One; 2016; 11(2):e0148678. PubMed ID: 26872363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B Kinase.
    Song LN; Silva J; Koller A; Rosenthal A; Chen EI; Gelmann EP
    Mol Cancer Res; 2015 May; 13(5):913-22. PubMed ID: 25777618
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
    Bowen C; Ostrowski MC; Leone G; Gelmann EP
    Cancer Res; 2019 Aug; 79(16):4124-4134. PubMed ID: 31213464
    [No Abstract]   [Full Text] [Related]  

  • 9. p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line.
    Jiang A; Yu C; Zhang P; Chen W; Liu W; Hu X; Zhang J
    Exp Mol Med; 2006 Dec; 38(6):625-33. PubMed ID: 17202838
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of phosphorylation sites of TOPORS and a role for serine 98 in the regulation of ubiquitin but not SUMO E3 ligase activity.
    Park HJ; Zheng H; Kulkarni D; Kerrigan J; Pungaliya P; Saleem A; Rubin EH
    Biochemistry; 2008 Dec; 47(52):13887-96. PubMed ID: 19053840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1.
    Markowski MC; Bowen C; Gelmann EP
    Cancer Res; 2008 Sep; 68(17):6896-901. PubMed ID: 18757402
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss.
    Lei Q; Jiao J; Xin L; Chang CJ; Wang S; Gao J; Gleave ME; Witte ON; Liu X; Wu H
    Cancer Cell; 2006 May; 9(5):367-78. PubMed ID: 16697957
    [TBL] [Abstract][Full Text] [Related]  

  • 13. topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage.
    Lin L; Ozaki T; Takada Y; Kageyama H; Nakamura Y; Hata A; Zhang JH; Simonds WF; Nakagawara A; Koseki H
    Oncogene; 2005 May; 24(21):3385-96. PubMed ID: 15735665
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional activation of ATM by the prostate cancer suppressor NKX3.1.
    Bowen C; Ju JH; Lee JH; Paull TT; Gelmann EP
    Cell Rep; 2013 Aug; 4(3):516-29. PubMed ID: 23890999
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse models.
    Linn DE; Bronson RT; Li Z
    PLoS One; 2015; 10(3):e0120628. PubMed ID: 25780911
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis.
    Li Y; Zhou Z; Chen C
    Cell Death Differ; 2008 Dec; 15(12):1941-51. PubMed ID: 18806757
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.
    Pungaliya P; Kulkarni D; Park HJ; Marshall H; Zheng H; Lackland H; Saleem A; Rubin EH
    J Proteome Res; 2007 Oct; 6(10):3918-23. PubMed ID: 17803295
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1.
    Bergiers I; Bridoux L; Nguyen N; Twizere JC; Rezsöhazy R
    PLoS One; 2013; 8(11):e80387. PubMed ID: 24244684
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor.
    Saleem A; Dutta J; Malegaonkar D; Rasheed F; Rasheed Z; Rajendra R; Marshall H; Luo M; Li H; Rubin EH
    Oncogene; 2004 Jul; 23(31):5293-300. PubMed ID: 15107820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [TUMOR SUPPRESSOR p63 REGULATES EXPRESSION OF UBIQUITIN LIGASE Pirh2].
    Daks AA; Petukhov AV; Shuvalov OY; Vasilieva EA; Melino G; Barlev NA; Fedorova OA
    Tsitologiia; 2015; 57(12):876-9. PubMed ID: 26995965
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.