These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 18081312)

  • 1. Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate.
    Van Vleet JL; Reinhardt LA; Miller BG; Sievers A; Cleland WW
    Biochemistry; 2008 Jan; 47(2):798-803. PubMed ID: 18081312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A substantial oxygen isotope effect at O2 in the OMP decarboxylase reaction: mechanistic implications.
    Wepukhulu WO; Smiley VL; Vemulapalli B; Smiley JA; Phillips LM; Lee JK
    Org Biomol Chem; 2008 Dec; 6(24):4533-41. PubMed ID: 19039361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantum and classical simulations of orotidine monophosphate decarboxylase: support for a direct decarboxylation mechanism.
    Vardi-Kilshtain A; Doron D; Major DT
    Biochemistry; 2013 Jun; 52(25):4382-90. PubMed ID: 23692207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular dynamic study of orotidine-5'-monophosphate decarboxylase in ground state and in intermediate state: a role of the 203-218 loop dynamics.
    Hur S; Bruice TC
    Proc Natl Acad Sci U S A; 2002 Jul; 99(15):9668-73. PubMed ID: 12107279
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A proficient enzyme: insights on the mechanism of orotidine monophosphate decarboxylase from computer simulations.
    Raugei S; Cascella M; Carloni P
    J Am Chem Soc; 2004 Dec; 126(48):15730-7. PubMed ID: 15571395
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interrogation of the active site of OMP decarboxylase from Escherichia coli with a substrate analogue bearing an anionic group at C6.
    Thirumalairajan S; Mahaney B; Bearne SL
    Chem Commun (Camb); 2010 May; 46(18):3158-60. PubMed ID: 20424759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for the decarboxylation of orotidine 5'-monophosphate (OMP) by Plasmodium falciparum OMP decarboxylase.
    Tokuoka K; Kusakari Y; Krungkrai SR; Matsumura H; Kai Y; Krungkrai J; Horii T; Inoue T
    J Biochem; 2008 Jan; 143(1):69-78. PubMed ID: 17981823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase.
    Sievers A; Wolfenden R
    Bioorg Chem; 2005 Feb; 33(1):45-52. PubMed ID: 15668182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: mechanistic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase.
    Yew WS; Wise EL; Rayment I; Gerlt JA
    Biochemistry; 2004 Jun; 43(21):6427-37. PubMed ID: 15157077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: crystallographic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase.
    Wise EL; Yew WS; Gerlt JA; Rayment I
    Biochemistry; 2004 Jun; 43(21):6438-46. PubMed ID: 15157078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzymatic reactions involving novel mechanisms of carbanion stabilization.
    Begley TP; Ealick SE
    Curr Opin Chem Biol; 2004 Oct; 8(5):508-15. PubMed ID: 15450493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Theoretical studies of the effect of thio substitution on orotidine monophosphate decarboxylase substrates.
    Phillips LM; Lee JK
    J Org Chem; 2005 Feb; 70(4):1211-21. PubMed ID: 15704953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: effect of solvent viscosity on kinetic constants.
    Wood BM; Chan KK; Amyes TL; Richard JP; Gerlt JA
    Biochemistry; 2009 Jun; 48(24):5510-7. PubMed ID: 19435313
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.
    Tsang WY; Wood BM; Wong FM; Wu W; Gerlt JA; Amyes TL; Richard JP
    J Am Chem Soc; 2012 Sep; 134(35):14580-94. PubMed ID: 22812629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions.
    Goryanova B; Goldman LM; Amyes TL; Gerlt JA; Richard JP
    Biochemistry; 2013 Oct; 52(42):7500-11. PubMed ID: 24053466
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.
    Toth K; Amyes TL; Wood BM; Chan K; Gerlt JA; Richard JP
    J Am Chem Soc; 2010 May; 132(20):7018-24. PubMed ID: 20441167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Transition State Stabilization Dominates Over Ground State Destabilization.
    Goryanova B; Amyes TL; Richard JP
    J Am Chem Soc; 2019 Aug; 141(34):13468-13478. PubMed ID: 31365243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catalytic proficiency: the unusual case of OMP decarboxylase.
    Miller BG; Wolfenden R
    Annu Rev Biochem; 2002; 71():847-85. PubMed ID: 12045113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An alternative explanation for the catalytic proficiency of orotidine 5'-phosphate decarboxylase.
    Lee TS; Chong LT; Chodera JD; Kollman PA
    J Am Chem Soc; 2001 Dec; 123(51):12837-48. PubMed ID: 11749542
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design.
    Wittmann JG; Heinrich D; Gasow K; Frey A; Diederichsen U; Rudolph MG
    Structure; 2008 Jan; 16(1):82-92. PubMed ID: 18184586
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.