BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 18083562)

  • 21. The effect of thiamine supplementation on tumour proliferation. A metabolic control analysis study.
    Comín-Anduix B; Boren J; Martinez S; Moro C; Centelles JJ; Trebukhina R; Petushok N; Lee WN; Boros LG; Cascante M
    Eur J Biochem; 2001 Aug; 268(15):4177-82. PubMed ID: 11488910
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Role of thiamin (vitamin B-1) and transketolase in tumor cell proliferation.
    Cascante M; Centelles JJ; Veech RL; Lee WN; Boros LG
    Nutr Cancer; 2000; 36(2):150-4. PubMed ID: 10890024
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Orally active factor Xa inhibitors: investigation of a novel series of 3-amidinophenylsulfonamide derivatives using an amidoxime prodrug strategy.
    Uchida M; Okazaki K; Mukaiyama H; Isawa H; Kobayashi H; Shiohara H; Muranaka H; Kai Y; Kikuchi N; Takeuchi H; Yokoyama K; Tsuji E; Ozawa T; Hoyano Y; Koizumi T; Misawa K; Hara K; Nakano S; Murakami Y; Okuno H
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4682-7. PubMed ID: 18667303
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, biochemical, and cellular evaluation of farnesyl monophosphate prodrugs as farnesyltransferase inhibitors.
    Clark MK; Scott SA; Wojtkowiak J; Chirco R; Mathieu P; Reiners JJ; Mattingly RR; Borch RF; Gibbs RA
    J Med Chem; 2007 Jul; 50(14):3274-82. PubMed ID: 17555307
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Serendipitous discovery of a prodrug of a PARP-1 inhibitor.
    Dunn D; Husten J; Aimone LD; Ator MA; Chatterjee S
    Chem Biol Drug Des; 2013 Sep; 82(3):348-50. PubMed ID: 23679830
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.
    Schmid U; Stopper H; Heidland A; Schupp N
    Diabetes Metab Res Rev; 2008; 24(5):371-7. PubMed ID: 18384109
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Innovative Electrochemical Screening Allows Transketolase Inhibitors to Be Identified.
    Aymard CMG; Halma M; Comte A; Mousty C; Prévot V; Hecquet L; Charmantray F; Blum LJ; Doumèche B
    Anal Chem; 2018 Aug; 90(15):9241-9248. PubMed ID: 29950093
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Velázquez C; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem; 2008 Nov; 16(22):9694-8. PubMed ID: 18930406
    [TBL] [Abstract][Full Text] [Related]  

  • 29. An efficient amperometric transketolase assay: towards inhibitor screening.
    Touisni N; Charmantray F; Hélaine V; Hecquet L; Mousty C
    Biosens Bioelectron; 2014 Dec; 62():90-6. PubMed ID: 24984289
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.
    Sakagami K; Yasuhara A; Chaki S; Yoshikawa R; Kawakita Y; Saito A; Taguchi T; Nakazato A
    Bioorg Med Chem; 2008 Apr; 16(8):4359-66. PubMed ID: 18348906
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.
    Masini T; Lacy B; Monjas L; Hawksley D; de Voogd AR; Illarionov B; Iqbal A; Leeper FJ; Fischer M; Kontoyianni M; Hirsch AK
    Org Biomol Chem; 2015 Dec; 13(46):11263-77. PubMed ID: 26411373
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis and evaluation of novel prodrugs of caspase inhibitors.
    Charrier JD; Durrant SJ; Studley J; Lawes L; Weber P
    Bioorg Med Chem Lett; 2012 Jan; 22(1):485-8. PubMed ID: 22104150
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis of a novel prodrug of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans-propenoic acid for colon delivery.
    Curini M; Epifano F; Genovese S
    Bioorg Med Chem Lett; 2005 Nov; 15(22):5049-52. PubMed ID: 16165357
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A protecting group-free synthesis of deazathiamine: a step toward inhibitor design.
    Zhao H; de Carvalho LP; Nathan C; Ouerfelli O
    Bioorg Med Chem Lett; 2010 Nov; 20(22):6472-4. PubMed ID: 20943392
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Discovery of phosphonic diamide prodrugs and their use for the oral delivery of a series of fructose 1,6-bisphosphatase inhibitors.
    Dang Q; Kasibhatla SR; Jiang T; Fan K; Liu Y; Taplin F; Schulz W; Cashion DK; Reddy KR; van Poelje PD; Fujitaki JM; Potter SC; Erion MD
    J Med Chem; 2008 Jul; 51(14):4331-9. PubMed ID: 18570362
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.
    Lu H; Tonge PJ
    Acc Chem Res; 2008 Jan; 41(1):11-20. PubMed ID: 18193820
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.
    Payne JE; Bonnefous C; Hassig CA; Symons KT; Guo X; Nguyen PM; Annable T; Wash PL; Hoffman TZ; Rao TS; Shiau AK; Malecha JW; Noble SA; Hager JH; Smith ND
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6093-6. PubMed ID: 18954983
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens.
    Fu L; Jiang Z; Cai Z; Liu X; He H; Yang Y
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5407-10. PubMed ID: 19682897
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Antithiamine effect of methyl sinapate on the growth of Staphylococcus aureus & on rat erythrocyte transketolase activity.
    Bhattacharya J; Chaudhuri DK
    Indian J Exp Biol; 1975 Sep; 13(5):474-5. PubMed ID: 1218906
    [No Abstract]   [Full Text] [Related]  

  • 40. Transketolase: observations in alcohol-related brain damage research.
    Alexander-Kaufman K; Harper C
    Int J Biochem Cell Biol; 2009 Apr; 41(4):717-20. PubMed ID: 18490188
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.