BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 18085744)

  • 1. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.
    Jarkas N; Voll RJ; Williams L; Votaw JR; Owens M; Goodman MM
    J Med Chem; 2008 Jan; 51(2):271-81. PubMed ID: 18085744
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
    Huang Y; Bae SA; Zhu Z; Guo N; Roth BL; Laruelle M
    J Med Chem; 2005 Apr; 48(7):2559-70. PubMed ID: 15801845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.
    Goodman MM; Chen P; Plisson C; Martarello L; Galt J; Votaw JR; Kilts CD; Malveaux G; Camp VM; Shi B; Ely TD; Howell L; McConathy J; Nemeroff CB
    J Med Chem; 2003 Mar; 46(6):925-35. PubMed ID: 12620070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Validation of two fluoro-analogues of N,N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)benzylamine as serotonin transporter imaging agents using microPET.
    Jarkas N; Voll RJ; Williams L; Goodman MM
    Nucl Med Biol; 2010 Jul; 37(5):593-603. PubMed ID: 20610164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.
    Jarkas N; McConathy J; Voll RJ; Goodman MM
    J Med Chem; 2005 Jun; 48(13):4254-65. PubMed ID: 15974579
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent.
    Plisson C; Stehouwer JS; Voll RJ; Howell L; Votaw JR; Owens MJ; Goodman MM
    J Med Chem; 2007 Sep; 50(19):4553-60. PubMed ID: 17705359
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.
    Plisson C; McConathy J; Martarello L; Malveaux EJ; Camp VM; Williams L; Votaw JR; Goodman MM
    J Med Chem; 2004 Feb; 47(5):1122-35. PubMed ID: 14971892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters.
    Jarkas N; Votaw JR; Voll RJ; Williams L; Camp VM; Owens MJ; Purselle DC; Bremner JD; Kilts CD; Nemeroff CB; Goodman MM
    Nucl Med Biol; 2005 Apr; 32(3):211-24. PubMed ID: 15820756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
    Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard JC; Halldin C; Guilloteau D
    J Pharmacol Exp Ther; 2003 Jan; 304(1):81-7. PubMed ID: 12490578
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New PET imaging agent for the serotonin transporter: [(18)F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine).
    Oya S; Choi SR; Coenen H; Kung HF
    J Med Chem; 2002 Oct; 45(21):4716-23. PubMed ID: 12361398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.
    Jarkas N; McConathy J; Votaw JR; Voll RJ; Malveaux E; Camp VM; Williams L; Goodman RR; Kilts CD; Goodman MM
    Nucl Med Biol; 2005 Jan; 32(1):75-86. PubMed ID: 15691664
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging.
    Mavel S; Vercouillie J; Garreau L; Raguza T; Ravna AW; Chalon S; Guilloteau D; Emond P
    Bioorg Med Chem; 2008 Oct; 16(19):9050-5. PubMed ID: 18793858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The new PET imaging agent [11C]AFE is a selective serotonin transporter ligand with fast brain uptake kinetics.
    Zhu Z; Guo N; Narendran R; Erritzoe D; Ekelund J; Hwang DR; Bae SA; Laruelle M; Huang Y
    Nucl Med Biol; 2004 Nov; 31(8):983-94. PubMed ID: 15607480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: an improved serotonin transporter imaging agent.
    Kung HF; Newman S; Choi SR; Oya S; Hou C; Zhuang ZP; Acton PD; Plössl K; Winkler J; Kung MP
    J Med Chem; 2004 Oct; 47(21):5258-64. PubMed ID: 15456270
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An improved synthesis of 4-[18F]-ADAM, a potent serotonin transporter imaging agent.
    Huang YY; Huang WS; Chu TC; Shiue CY
    Appl Radiat Isot; 2009 Jun; 67(6):1063-7. PubMed ID: 19339192
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N,N-dimethyl-2-(2-amino-4-(18)F-fluorophenylthio)-benzylamine (4-(18)F-ADAM): an improved PET radioligand for serotonin transporters.
    Shiue GG; Choi SR; Fang P; Hou C; Acton PD; Cardi C; Saffer JR; Greenberg JH; Karp JS; Kung HF; Shiue CY
    J Nucl Med; 2003 Dec; 44(12):1890-7. PubMed ID: 14660713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands.
    Vercouillie J; Mavel S; Galineau L; Ragusa T; Innis R; Kassiou M; Chalon S; Dollé F; Besnard JC; Guilloteau D; Emond P
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1297-300. PubMed ID: 16337793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FlipADAM: a potential new SPECT imaging agent for the serotonin transporter.
    Wang JL; Deutsch EC; Oya S; Kung HF
    Nucl Med Biol; 2010 Jul; 37(5):577-86. PubMed ID: 20610162
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB).
    Li Q; Ma L; Innis RB; Seneca N; Ichise M; Huang H; Laruelle M; Murphy DL
    J Pharmacol Exp Ther; 2004 Feb; 308(2):481-6. PubMed ID: 14610240
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of FlipIDAM as a SERT-selective SPECT imaging agent.
    Lemoine L; Lieberman BP; Ploessl K; Zheng P; Kung HF
    Nucl Med Biol; 2013 Oct; 40(7):879-86. PubMed ID: 23856117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.