These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 18085786)

  • 1. A mechanistic design principle for protein tyrosine kinase sensors: application to a validated cancer target.
    Wakata A; Cahill SM; Blumenstein M; Gunby RH; Jockusch S; Marti AA; Cimbro B; Gambacorti-Passerini C; Donella-Deana A; Pinna LA; Turro NJ; Lawrence DS
    Org Lett; 2008 Jan; 10(2):301-4. PubMed ID: 18085786
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Self-reporting fluorescent substrates of protein tyrosine kinases.
    Wang Q; Cahill SM; Blumenstein M; Lawrence DS
    J Am Chem Soc; 2006 Feb; 128(6):1808-9. PubMed ID: 16464077
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase.
    Tartari CJ; Gunby RH; Coluccia AM; Sottocornola R; Cimbro B; Scapozza L; Donella-Deana A; Pinna LA; Gambacorti-Passerini C
    J Biol Chem; 2008 Feb; 283(7):3743-50. PubMed ID: 18070884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity.
    Donella-Deana A; Marin O; Cesaro L; Gunby RH; Ferrarese A; Coluccia AM; Tartari CJ; Mologni L; Scapozza L; Gambacorti-Passerini C; Pinna LA
    Biochemistry; 2005 Jun; 44(23):8533-42. PubMed ID: 15938644
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway.
    Souttou B; Carvalho NB; Raulais D; Vigny M
    J Biol Chem; 2001 Mar; 276(12):9526-31. PubMed ID: 11121404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.
    Cussac D; Greenland C; Roche S; Bai RY; Duyster J; Morris SW; Delsol G; Allouche M; Payrastre B
    Blood; 2004 Feb; 103(4):1464-71. PubMed ID: 14563642
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin.
    Bonvini P; Gastaldi T; Falini B; Rosolen A
    Cancer Res; 2002 Mar; 62(5):1559-66. PubMed ID: 11888936
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma.
    Zhang Q; Raghunath PN; Xue L; Majewski M; Carpentieri DF; Odum N; Morris S; Skorski T; Wasik MA
    J Immunol; 2002 Jan; 168(1):466-74. PubMed ID: 11751994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.
    Christensen JG; Zou HY; Arango ME; Li Q; Lee JH; McDonnell SR; Yamazaki S; Alton GR; Mroczkowski B; Los G
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3314-22. PubMed ID: 18089725
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein.
    Ergin M; Denning MF; Izban KF; Amin HM; Martinez RL; Saeed S; Alkan S
    Exp Hematol; 2001 Sep; 29(9):1082-90. PubMed ID: 11532349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BCL-3 overexpression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Rassidakis GZ; Oyarzo MP; Medeiros LJ
    Blood; 2003 Aug; 102(3):1146-7. PubMed ID: 12869493
    [No Abstract]   [Full Text] [Related]  

  • 12. Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation.
    Perez-Pinera P; Zhang W; Chang Y; Vega JA; Deuel TF
    J Biol Chem; 2007 Sep; 282(39):28683-28690. PubMed ID: 17681947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anaplastic lymphoma kinase as a therapeutic target in anaplastic large cell lymphoma, non-small cell lung cancer and neuroblastoma.
    Cheng M; Ott GR
    Anticancer Agents Med Chem; 2010 Mar; 10(3):236-49. PubMed ID: 20406193
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.
    Wange RL; Guitián R; Isakov N; Watts JD; Aebersold R; Samelson LE
    J Biol Chem; 1995 Aug; 270(32):18730-3. PubMed ID: 7642520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A ligand-inducible epidermal growth factor receptor/anaplastic lymphoma kinase chimera promotes mitogenesis and transforming properties in 3T3 cells.
    Piccinini G; Bacchiocchi R; Serresi M; Vivani C; Rossetti S; Gennaretti C; Carbonari D; Fazioli F
    J Biol Chem; 2002 Jun; 277(25):22231-9. PubMed ID: 11919185
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nucleophosmin-anaplastic lymphoma kinase: the ultimate oncogene and therapeutic target.
    Werner MT; Zhao C; Zhang Q; Wasik MA
    Blood; 2017 Feb; 129(7):823-831. PubMed ID: 27879258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
    Lee CC; Jia Y; Li N; Sun X; Ng K; Ambing E; Gao MY; Hua S; Chen C; Kim S; Michellys PY; Lesley SA; Harris JL; Spraggon G
    Biochem J; 2010 Sep; 430(3):425-37. PubMed ID: 20632993
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel ALK fusion in anaplastic large cell lymphoma involving EEF1G, a subunit of the eukaryotic elongation factor-1 complex.
    Palacios G; Shaw TI; Li Y; Singh RK; Valentine M; Sandlund JT; Lim MS; Mullighan CG; Leventaki V
    Leukemia; 2017 Mar; 31(3):743-747. PubMed ID: 27840423
    [No Abstract]   [Full Text] [Related]  

  • 19. Seeing is believing: peptide-based fluorescent sensors of protein tyrosine kinase activity.
    Lawrence DS; Wang Q
    Chembiochem; 2007 Mar; 8(4):373-8. PubMed ID: 17243187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).
    Ouyang T; Bai RY; Bassermann F; von Klitzing C; Klumpen S; Miething C; Morris SW; Peschel C; Duyster J
    J Biol Chem; 2003 Aug; 278(32):30028-36. PubMed ID: 12748172
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.