BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

94 related articles for article (PubMed ID: 1808614)

  • 1. Simultaneous modeling of the pharmacokinetics and methemoglobin pharmacodynamics of an 8-aminoquinoline candidate antimalarial (WR 238605).
    Brueckner RP; Fleckenstein L
    Pharm Res; 1991 Dec; 8(12):1505-10. PubMed ID: 1808614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methemoglobin formation resulting from administration of candidate 8-aminoquinoline antiparasitic drugs in the dog.
    Anders JC; Chung H; Theoharides AD
    Fundam Appl Toxicol; 1988 Feb; 10(2):270-5. PubMed ID: 3356313
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetics and kinetic-dynamic modeling of an 8-aminoquinoline candidate anticyanide and antimalarial drug (WR242511).
    Marino MT; Peggins JO; Brown LD; Urquhart MR; Brewer TG
    Drug Metab Dispos; 1994; 22(3):358-66. PubMed ID: 8070311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial.
    Brueckner RP; Lasseter KC; Lin ET; Schuster BG
    Am J Trop Med Hyg; 1998 May; 58(5):645-9. PubMed ID: 9598455
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511).
    Rockwood G; Duniho S; Briscoe C; Gold M; Armstrong K; Kahler D; Moran A; Baskin S
    J Med Toxicol; 2008 Sep; 4(3):157-66. PubMed ID: 18821488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of methemoglobin formers in protection against the toxic effects of cyanide.
    Scharf BA; Fricke RF; Baskin SI
    Gen Pharmacol; 1992 Jan; 23(1):19-25. PubMed ID: 1592224
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An improved pharmacodynamic model for formation of methemoglobin by antimalarial drugs.
    Fasanmade AA; Jusko WJ
    Drug Metab Dispos; 1995 May; 23(5):573-6. PubMed ID: 7587933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Formation of methemoglobin and metmyoglobin using 8-aminoquinoline derivatives or sodium nitrite and subsequent reaction with cyanide.
    Steinhaus RK; Baskin SI; Clark JH; Kirby SD
    J Appl Toxicol; 1990 Oct; 10(5):345-51. PubMed ID: 2254586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rapid and sensitive quantitative analysis of the new antimalarial N4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8- quinolinyl]-1,4-pentanediamine in plasma by liquid chromatography and electrochemical detection.
    Karle JM; Olmeda R
    J Chromatogr; 1988 Feb; 424(2):347-56. PubMed ID: 3372627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Population pharmacokinetics of tafenoquine during malaria prophylaxis in healthy subjects.
    Charles BG; Miller AK; Nasveld PE; Reid MG; Harris IE; Edstein MD
    Antimicrob Agents Chemother; 2007 Aug; 51(8):2709-15. PubMed ID: 17517850
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantification of the individual enantiomer plasma concentrations of the candidate antimalarial agent N4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8-quinolinyl] - 1,4-pentanediamine (WR 238,605).
    Karle JM; Olmeda R; Freeman SG; Schroeder AC
    J Chromatogr B Biomed Appl; 1995 Aug; 670(2):251-7. PubMed ID: 8548015
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
    O'Neill PM; Park BK; Shone AE; Maggs JL; Roberts P; Stocks PA; Biagini GA; Bray PG; Gibbons P; Berry N; Winstanley PA; Mukhtar A; Bonar-Law R; Hindley S; Bambal RB; Davis CB; Bates M; Hart TK; Gresham SL; Lawrence RM; Brigandi RA; Gomez-delas-Heras FM; Gargallo DV; Ward SA
    J Med Chem; 2009 Mar; 52(5):1408-15. PubMed ID: 19222165
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Population pharmacokinetics of the new antimalarial agent tafenoquine in Thai soldiers.
    Edstein MD; Kocisko DA; Brewer TG; Walsh DS; Eamsila C; Charles BG
    Br J Clin Pharmacol; 2001 Dec; 52(6):663-70. PubMed ID: 11736877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of drug accumulation in 4-aminoquinoline antimalarial potency. The influence of structural substitution and physicochemical properties.
    Hawley SR; Bray PG; O'Neill PM; Park BK; Ward SA
    Biochem Pharmacol; 1996 Sep; 52(5):723-33. PubMed ID: 8765470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of a candidate 8-aminoquinoline antimalarial agent, WR 238605, by rat liver microsomes.
    Idowu OR; Peggins JO; Brewer TG; Kelley C
    Drug Metab Dispos; 1995 Jan; 23(1):1-17. PubMed ID: 7720510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A simple and rapid evaluation of methemoglobin toxicity of 8-aminoquinolines and related compounds.
    Srivastava P; Singh S; Jain GK; Puri SK; Pandey VC
    Ecotoxicol Environ Saf; 2000 Mar; 45(3):236-9. PubMed ID: 10702341
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of new 4-aminoquinolines and quinoline-acridine hybrids as antimalarial agents.
    Kumar A; Srivastava K; Kumar SR; Puri SK; Chauhan PM
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7059-63. PubMed ID: 20951034
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetics and kinetic-dynamic modelling of aminophenones as methaemoglobin formers.
    Marino MT; Urquhart MR; Sperry ML; Bredow JV; Brown LD; Lin E; Brewer TG
    J Pharm Pharmacol; 1997 Mar; 49(3):282-7. PubMed ID: 9231346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetics of the anti-leishmanian agent WR 6026 in dogs.
    Taylor T; Hawkins DR; Morris GR; Chung H
    Eur J Drug Metab Pharmacokinet; 1991; Spec No 3():136-9. PubMed ID: 1820868
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antimalarials. 16. Synthesis of 2-substituted analogues of 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3- (trifluoromethyl)phenoxy]quinoline as candidate antimalarials.
    LaMontagne MP; Blumbergs P; Smith DC
    J Med Chem; 1989 Aug; 32(8):1728-32. PubMed ID: 2666665
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.