These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 18086527)

  • 1. Molecular modeling study and synthesis of novel pyrrolo[2,3-d]pyrimidines and pyrrolotriazolopyrimidines of expected antitumor and radioprotective activities.
    Abou El Ella DA; Ghorab MM; Noaman E; Heiba HI; Khalil AI
    Bioorg Med Chem; 2008 Mar; 16(5):2391-402. PubMed ID: 18086527
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of some new pyrazolo[3,4-d]pyrimidine derivatives of expected anticancer and radioprotective activity.
    Ghorab MM; Ragab FA; Alqasoumi SI; Alafeefy AM; Aboulmagd SA
    Eur J Med Chem; 2010 Jan; 45(1):171-8. PubMed ID: 19853327
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel antitumor and radioprotective sulfonamides containing pyrrolo [2,3-d]pyrimidines.
    Ghorab MM; Noaman E; Ismail MM; Heiba HI; Ammar YA; Sayed MY
    Arzneimittelforschung; 2006; 56(6):405-13. PubMed ID: 16889123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of some novel sulfur containing triazolothienopyrimidines and biscompounds as possible antitumor and radioprotective agents.
    Heiba HI; Ragab FA; Noaman E; Ghorab MM; Galal M
    Arzneimittelforschung; 2006; 56(8):593-9. PubMed ID: 17009841
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of certain new thiieno [2,3-d] pyrimidines as potential antitumor and radioprotective agents.
    Ghorab MM; Ragab FA; Noaman E; Heiba HI; Galal M
    Arzneimittelforschung; 2006; 56(7):553-60. PubMed ID: 16927539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel synthesis of pyrrolo [2,3-d] pyrimidines bearing sulfonamide moieties as potential antitumor and radioprotective agents.
    Ismail MM; Ghorab MM; Noaman E; Ammar YA; Heiba HI; Sayed MY
    Arzneimittelforschung; 2006; 56(4):301-8. PubMed ID: 16724517
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.
    Jung MH; Kim H; Choi WK; El-Gamal MI; Park JH; Yoo KH; Sim TB; Lee SH; Baek D; Hah JM; Cho JH; Oh CH
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6538-43. PubMed ID: 19857963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of novel pyrrole and pyrrolo[2,3-d]pyrimidine derivatives bearing sulfonamide moiety for evaluation as anticancer and radiosensitizing agents.
    Ghorab MM; Ragab FA; Heiba HI; Youssef HA; El-Gazzar MG
    Bioorg Med Chem Lett; 2010 Nov; 20(21):6316-20. PubMed ID: 20850308
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A convenient synthesis and molecular modeling study of novel purine and pyrimidine derivatives as CDK2/cyclin A3 inhibitors.
    Elgazwy AS; Ismail NS; Elzahabi HS
    Bioorg Med Chem; 2010 Nov; 18(21):7639-50. PubMed ID: 20851615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure based optimization of novel Akt inhibitors.
    Lippa B; Pan G; Corbett M; Li C; Kauffman GS; Pandit J; Robinson S; Wei L; Kozina E; Marr ES; Borzillo G; Knauth E; Barbacci-Tobin EG; Vincent P; Troutman M; Baker D; Rajamohan F; Kakar S; Clark T; Morris J
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3359-63. PubMed ID: 18456494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: a new class of Aurora-A kinase inhibitors.
    Moriarty KJ; Koblish HK; Garrabrant T; Maisuria J; Khalil E; Ali F; Petrounia IP; Crysler CS; Maroney AC; Johnson DL; Galemmo RA
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5778-83. PubMed ID: 16949284
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel Biginelli dihydropyrimidines with potential anticancer activity: a parallel synthesis and CoMSIA study.
    Prashantha Kumar BR; Sankar G; Nasir Baig RB; Chandrashekaran S
    Eur J Med Chem; 2009 Oct; 44(10):4192-8. PubMed ID: 19525040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors.
    Peifer C; Selig R; Kinkel K; Ott D; Totzke F; Schächtele C; Heidenreich R; Röcken M; Schollmeyer D; Laufer S
    J Med Chem; 2008 Jul; 51(13):3814-24. PubMed ID: 18529047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 1.
    Choi HS; Wang Z; Richmond W; He X; Yang K; Jiang T; Sim T; Karanewsky D; Gu XJ; Zhou V; Liu Y; Ohmori O; Caldwell J; Gray N; He Y
    Bioorg Med Chem Lett; 2006 Apr; 16(8):2173-6. PubMed ID: 16458503
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, antitumor evaluation, molecular modeling and quantitative structure-activity relationship (QSAR) of some novel arylazopyrazolodiazine and triazine analogs.
    El-Shafei A; Fadda AA; Khalil AM; Ameen TA; Badria FA
    Bioorg Med Chem; 2009 Jul; 17(14):5096-105. PubMed ID: 19527933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines.
    Kaspersen SJ; Sørum C; Willassen V; Fuglseth E; Kjøbli E; Bjørkøy G; Sundby E; Hoff BH
    Eur J Med Chem; 2011 Dec; 46(12):6002-14. PubMed ID: 22018877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides.
    Pudziuvelyte E; Ríos-Luci C; León LG; Cikotiene I; Padrón JM
    Bioorg Med Chem; 2009 Jul; 17(14):4955-60. PubMed ID: 19527934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel heterocyclic-fused pyrimidine derivatives: synthesis, molecular modeling and pharmacological screening.
    Arafa RK; Nour MS; El-Sayed NA
    Eur J Med Chem; 2013 Nov; 69():498-507. PubMed ID: 24090920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The discovery of novel vascular endothelial growth factor receptor tyrosine kinases inhibitors: pharmacophore modeling, virtual screening and docking studies.
    Yu H; Wang Z; Zhang L; Zhang J; Huang Q
    Chem Biol Drug Des; 2007 Mar; 69(3):204-11. PubMed ID: 17441906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biological evaluation of novel pyrimidine derivatives as CDK2 inhibitors.
    Ibrahim DA; El-Metwally AM
    Eur J Med Chem; 2010 Mar; 45(3):1158-66. PubMed ID: 20045222
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.