198 related articles for article (PubMed ID: 18089636)
1. Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.
Yan J; Chen S; Zhang Y; Li X; Li Y; Wu X; Yuan J; Robling AG; Kapur R; Chan RJ; Yang FC
Hum Mol Genet; 2008 Apr; 17(7):936-48. PubMed ID: 18089636
[TBL] [Abstract][Full Text] [Related]
2. Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1.
Mund JA; Park S; Smith AE; He Y; Jiang L; Hawley E; Roberson MJ; Mitchell DK; Abu-Sultanah M; Yuan J; Bessler WK; Sandusky G; Chen S; Zhang C; Rhodes SD; Clapp DW
J Biol Chem; 2020 Jul; 295(29):9948-9958. PubMed ID: 32471868
[TBL] [Abstract][Full Text] [Related]
3. Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
Yang FC; Chen S; Robling AG; Yu X; Nebesio TD; Yan J; Morgan T; Li X; Yuan J; Hock J; Ingram DA; Clapp DW
J Clin Invest; 2006 Nov; 116(11):2880-91. PubMed ID: 17053831
[TBL] [Abstract][Full Text] [Related]
4. Regulation of osteoclast apoptosis and motility by small GTPase binding protein Rac1.
Fukuda A; Hikita A; Wakeyama H; Akiyama T; Oda H; Nakamura K; Tanaka S
J Bone Miner Res; 2005 Dec; 20(12):2245-53. PubMed ID: 16294277
[TBL] [Abstract][Full Text] [Related]
5. c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions.
He Y; Rhodes SD; Chen S; Wu X; Yuan J; Yang X; Jiang L; Li X; Takahashi N; Xu M; Mohammad KS; Guise TA; Yang FC
PLoS One; 2012; 7(11):e46900. PubMed ID: 23144792
[TBL] [Abstract][Full Text] [Related]
6. Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis.
Rhodes SD; Yang H; Dong R; Menon K; He Y; Li Z; Chen S; Staser KW; Jiang L; Wu X; Yang X; Peng X; Mohammad KS; Guise TA; Xu M; Yang FC
J Bone Miner Res; 2015 Oct; 30(10):1840-51. PubMed ID: 25917016
[TBL] [Abstract][Full Text] [Related]
7. Ras dependent paracrine secretion of osteopontin by Nf1+/- osteoblasts promote osteoclast activation in a neurofibromatosis type I murine model.
Li H; Liu Y; Zhang Q; Jing Y; Chen S; Song Z; Yan J; Li Y; Wu X; Zhang X; Zhang Y; Case J; Yu M; Ingram DA; Yang FC
Pediatr Res; 2009 Jun; 65(6):613-8. PubMed ID: 19247213
[TBL] [Abstract][Full Text] [Related]
8. Aberrant Myeloid Differentiation Contributes to the Development of Osteoporosis in Neurofibromatosis Type 1.
Rhodes SD; Yang FC
Curr Osteoporos Rep; 2016 Feb; 14(1):10-5. PubMed ID: 26932441
[TBL] [Abstract][Full Text] [Related]
9. Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice.
Sharma R; Wu X; Rhodes SD; Chen S; He Y; Yuan J; Li J; Yang X; Li X; Jiang L; Kim ET; Stevenson DA; Viskochil D; Xu M; Yang FC
Hum Mol Genet; 2013 Dec; 22(23):4818-28. PubMed ID: 23863460
[TBL] [Abstract][Full Text] [Related]
10. Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.
Wang Y; Lebowitz D; Sun C; Thang H; Grynpas MD; Glogauer M
J Bone Miner Res; 2008 Feb; 23(2):260-70. PubMed ID: 17922611
[TBL] [Abstract][Full Text] [Related]
11. The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.
Vives V; Laurin M; Cres G; Larrousse P; Morichaud Z; Noel D; Côté JF; Blangy A
J Bone Miner Res; 2011 May; 26(5):1099-110. PubMed ID: 21542010
[TBL] [Abstract][Full Text] [Related]
12. Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes.
Sandsmark DK; Zhang H; Hegedus B; Pelletier CL; Weber JD; Gutmann DH
Cancer Res; 2007 May; 67(10):4790-9. PubMed ID: 17510408
[TBL] [Abstract][Full Text] [Related]
13. Rac deletion in osteoclasts causes severe osteopetrosis.
Croke M; Ross FP; Korhonen M; Williams DA; Zou W; Teitelbaum SL
J Cell Sci; 2011 Nov; 124(Pt 22):3811-21. PubMed ID: 22114304
[TBL] [Abstract][Full Text] [Related]
14. Methods to Investigate the Role of Rho GTPases in Osteoclast Function.
Morel A; Blangy A; Vives V
Methods Mol Biol; 2018; 1821():219-233. PubMed ID: 30062415
[TBL] [Abstract][Full Text] [Related]
15. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
Ingram DA; Hiatt K; King AJ; Fisher L; Shivakumar R; Derstine C; Wenning MJ; Diaz B; Travers JB; Hood A; Marshall M; Williams DA; Clapp DW
J Exp Med; 2001 Jul; 194(1):57-69. PubMed ID: 11435472
[TBL] [Abstract][Full Text] [Related]
16. Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42.
Gu J; Yang Z; Yuan L; Guo S; Wang D; Zhao N; Meng L; Liu H; Chen W; Ma J
Exp Cell Res; 2020 Nov; 396(1):112265. PubMed ID: 32898553
[TBL] [Abstract][Full Text] [Related]
17. A 3D scanning confocal imaging method measures pit volume and captures the role of Rac in osteoclast function.
Goldberg SR; Georgiou J; Glogauer M; Grynpas MD
Bone; 2012 Jul; 51(1):145-52. PubMed ID: 22561898
[TBL] [Abstract][Full Text] [Related]
18. Multiple increased osteoclast functions in individuals with neurofibromatosis type 1.
Stevenson DA; Yan J; He Y; Li H; Liu Y; Zhang Q; Jing Y; Guo Z; Zhang W; Yang D; Wu X; Hanson H; Li X; Staser K; Viskochil DH; Carey JC; Chen S; Miller L; Roberson K; Moyer-Mileur L; Yu M; Schwarz EL; Pasquali M; Yang FC
Am J Med Genet A; 2011 May; 155A(5):1050-9. PubMed ID: 21465658
[TBL] [Abstract][Full Text] [Related]
19. Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
Daginakatte GC; Gianino SM; Zhao NW; Parsadanian AS; Gutmann DH
Cancer Res; 2008 Dec; 68(24):10358-66. PubMed ID: 19074905
[TBL] [Abstract][Full Text] [Related]
20. Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.
Zhu M; Sun BH; Saar K; Simpson C; Troiano N; Dallas SL; Tiede-Lewis LM; Nevius E; Pereira JP; Weinstein RS; Tommasini SM; Insogna KL
J Bone Miner Res; 2016 Apr; 31(4):864-73. PubMed ID: 26496249
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]