BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 18089840)

  • 1. A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats.
    McGaraughty S; Chu KL; Scanio MJ; Kort ME; Faltynek CR; Jarvis MF
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1204-11. PubMed ID: 18089840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
    Jarvis MF; Honore P; Shieh CC; Chapman M; Joshi S; Zhang XF; Kort M; Carroll W; Marron B; Atkinson R; Thomas J; Liu D; Krambis M; Liu Y; McGaraughty S; Chu K; Roeloffs R; Zhong C; Mikusa JP; Hernandez G; Gauvin D; Wade C; Zhu C; Pai M; Scanio M; Shi L; Drizin I; Gregg R; Matulenko M; Hakeem A; Gross M; Johnson M; Marsh K; Wagoner PK; Sullivan JP; Faltynek CR; Krafte DS
    Proc Natl Acad Sci U S A; 2007 May; 104(20):8520-5. PubMed ID: 17483457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain.
    Xu J; Chu KL; Zhu CZ; Niforatos W; Swensen A; Searle X; Lee L; Jarvis MF; McGaraughty S
    J Neurophysiol; 2014 Jan; 111(2):394-404. PubMed ID: 24155005
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats.
    McGaraughty S; Chu KL; Faltynek CR; Jarvis MF
    J Neurophysiol; 2006 Jan; 95(1):18-25. PubMed ID: 16162831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats.
    McGaraughty S; Chu KL; Brown BS; Zhu CZ; Zhong C; Joshi SK; Honore P; Faltynek CR; Jarvis MF
    J Neurophysiol; 2008 Dec; 100(6):3158-66. PubMed ID: 18829846
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury.
    Zhang XF; Zhu CZ; Thimmapaya R; Choi WS; Honore P; Scott VE; Kroeger PE; Sullivan JP; Faltynek CR; Gopalakrishnan M; Shieh CC
    Brain Res; 2004 May; 1009(1-2):147-58. PubMed ID: 15120592
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain.
    Brignell JL; Chapman V; Kendall DA
    Brain Res; 2008 Jun; 1215():87-96. PubMed ID: 18479674
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models.
    Joshi SK; Honore P; Hernandez G; Schmidt R; Gomtsyan A; Scanio M; Kort M; Jarvis MF
    J Pain; 2009 Mar; 10(3):306-15. PubMed ID: 19070548
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats.
    McGaraughty S; Chu KL; Perner RJ; Didomenico S; Kort ME; Kym PR
    Mol Pain; 2010 Mar; 6():14. PubMed ID: 20205719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat-evoked responses of dorsal horn neurons in naïve, carrageenan-inflamed and neuropathic rats.
    Jhaveri MD; Elmes SJ; Kendall DA; Chapman V
    Eur J Neurosci; 2005 Jul; 22(2):361-70. PubMed ID: 16045489
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions of spinal and peripheral CB(2) receptors.
    McGaraughty S; Chu KL; Dart MJ; Yao BB; Meyer MD
    Neuroscience; 2009 Feb; 158(4):1652-61. PubMed ID: 19063946
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased WDR spontaneous activity and receptive field size in rats following a neuropathic or inflammatory injury: implications for mechanical sensitivity.
    Chu KL; Faltynek CR; Jarvis MF; McGaraughty S
    Neurosci Lett; 2004 Nov; 372(1-2):123-6. PubMed ID: 15531101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain.
    Chu KL; Chandran P; Joshi SK; Jarvis MF; Kym PR; McGaraughty S
    Brain Res; 2011 Jan; 1369():158-66. PubMed ID: 21047496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.
    Kort ME; Drizin I; Gregg RJ; Scanio MJ; Shi L; Gross MF; Atkinson RN; Johnson MS; Pacofsky GJ; Thomas JB; Carroll WA; Krambis MJ; Liu D; Shieh CC; Zhang X; Hernandez G; Mikusa JP; Zhong C; Joshi S; Honore P; Roeloffs R; Marsh KC; Murray BP; Liu J; Werness S; Faltynek CR; Krafte DS; Jarvis MF; Chapman ML; Marron BE
    J Med Chem; 2008 Feb; 51(3):407-16. PubMed ID: 18176998
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pre-emptive intrathecal quinidine alleviates spinal nerve ligation-induced peripheral neuropathic pain.
    Cheng KI; Wang HC; Lai CS; Tsai HP; Kwan AL; Ho ST; Wang JJ; Chang LL
    J Pharm Pharmacol; 2011 Aug; 63(8):1063-9. PubMed ID: 21718290
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chronic spinal nerve ligation induces changes in response characteristics of nociceptive spinal dorsal horn neurons and in their descending regulation originating in the periaqueductal gray in the rat.
    Pertovaara A; Kontinen VK; Kalso EA
    Exp Neurol; 1997 Oct; 147(2):428-36. PubMed ID: 9344567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of selective spinal nerve ligation on acetic acid-induced nociceptive responses and ASIC3 immunoreactivity in the rat dorsal root ganglion.
    Omori M; Yokoyama M; Matsuoka Y; Kobayashi H; Mizobuchi S; Itano Y; Morita K; Ichikawa H
    Brain Res; 2008 Jul; 1219():26-31. PubMed ID: 18534561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The effect of amitriptyline on ectopic discharge of primary afferent fibers in the L5 dorsal root in a rat model of neuropathic pain.
    Su X; Liang AH; Urban MO
    Anesth Analg; 2009 May; 108(5):1671-9. PubMed ID: 19372353
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat.
    Gould HJ; England JD; Soignier RD; Nolan P; Minor LD; Liu ZP; Levinson SR; Paul D
    J Pain; 2004 Jun; 5(5):270-80. PubMed ID: 15219259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats.
    Brochu RM; Dick IE; Tarpley JW; McGowan E; Gunner D; Herrington J; Shao PP; Ok D; Li C; Parsons WH; Stump GL; Regan CP; Lynch JJ; Lyons KA; McManus OB; Clark S; Ali Z; Kaczorowski GJ; Martin WJ; Priest BT
    Mol Pharmacol; 2006 Mar; 69(3):823-32. PubMed ID: 16301337
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.