BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 18092324)

  • 1. Mutant p53(R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis.
    Heinlein C; Krepulat F; Löhler J; Speidel D; Deppert W; Tolstonog GV
    Int J Cancer; 2008 Apr; 122(8):1701-9. PubMed ID: 18092324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SV40 T/t-antigen induces premature mammary gland involution by apoptosis and selects for p53 missense mutation in mammary tumors.
    Tzeng YJ; Zimmermann C; Guhl E; Berg B; Avantaggiati ML; Graessmann A
    Oncogene; 1998 Apr; 16(16):2103-14. PubMed ID: 9572491
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer.
    Wang S; Liu JC; Kim D; Datti A; Zacksenhaus E
    Breast Cancer Res; 2016 Jan; 18(1):9. PubMed ID: 26781438
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A transgenic mouse model for mammary carcinogenesis.
    Li B; Murphy KL; Laucirica R; Kittrell F; Medina D; Rosen JM
    Oncogene; 1998 Feb; 16(8):997-1007. PubMed ID: 9519874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice: suppression of apoptosis during the transition from preneoplasia to carcinoma.
    Shibata MA; Maroulakou IG; Jorcyk CL; Gold LG; Ward JM; Green JE
    Cancer Res; 1996 Jul; 56(13):2998-3003. PubMed ID: 8674054
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.
    van Miltenburg MH; van Nimwegen MJ; Tijdens I; Lalai R; Kuiper R; Klarenbeek S; Schouten PC; de Vries A; Jonkers J; van de Water B
    Br J Cancer; 2014 May; 110(11):2747-55. PubMed ID: 24809783
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact p53 and pRb binding region do not have this effect.
    Goetz F; Tzeng YJ; Guhl E; Merker J; Graessmann M; Graessmann A
    Oncogene; 2001 Apr; 20(18):2325-32. PubMed ID: 11402328
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
    Tang J; Feng Y; Kuick R; Green M; Green M; Sakamoto N; Kurosu Y; Lin J; Cho KR; Fearon ER
    Lab Invest; 2019 Oct; 99(10):1454-1469. PubMed ID: 31148594
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
    Hirner H; Günes C; Bischof J; Wolff S; Grothey A; Kühl M; Oswald F; Wegwitz F; Bösl MR; Trauzold A; Henne-Bruns D; Peifer C; Leithäuser F; Deppert W; Knippschild U
    PLoS One; 2012; 7(1):e29709. PubMed ID: 22235331
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
    Wijnhoven SW; Zwart E; Speksnijder EN; Beems RB; Olive KP; Tuveson DA; Jonkers J; Schaap MM; van den Berg J; Jacks T; van Steeg H; de Vries A
    Cancer Res; 2005 Sep; 65(18):8166-73. PubMed ID: 16166291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation.
    Nakayama M; Sakai E; Echizen K; Yamada Y; Oshima H; Han TS; Ohki R; Fujii S; Ochiai A; Robine S; Voon DC; Tanaka T; Taketo MM; Oshima M
    Oncogene; 2017 Oct; 36(42):5885-5896. PubMed ID: 28628120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice.
    Duan W; Ding H; Subler MA; Zhu WG; Zhang H; Stoner GD; Windle JJ; Otterson GA; Villalona-Calero MA
    Oncogene; 2002 Nov; 21(51):7831-8. PubMed ID: 12420220
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The p53 tumor suppressor gene and gene product.
    Levine AJ
    Princess Takamatsu Symp; 1989; 20():221-30. PubMed ID: 2488233
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus.
    Zelazny E; Li B; Anagnostopoulos AM; Coleman A; Perkins AS
    Exp Mol Pathol; 2001 Jun; 70(3):183-93. PubMed ID: 11417997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant p53 promotes epithelial-mesenchymal plasticity and enhances metastasis in mammary carcinomas of WAP-T mice.
    Lenfert E; Maenz C; Heinlein C; Jannasch K; Schumacher U; Pantel K; Tolstonog GV; Deppert W; Wegwitz F
    Int J Cancer; 2015 Mar; 136(6):E521-33. PubMed ID: 25195563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
    Lu X; Liu DP; Xu Y
    Oncogene; 2013 Jun; 32(23):2900-6. PubMed ID: 22824795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.
    Akli S; Van Pelt CS; Bui T; Multani AS; Chang S; Johnson D; Tucker S; Keyomarsi K
    Cancer Res; 2007 Aug; 67(15):7212-22. PubMed ID: 17671189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.
    Donehower LA; Godley LA; Aldaz CM; Pyle R; Shi YP; Pinkel D; Gray J; Bradley A; Medina D; Varmus HE
    Prog Clin Biol Res; 1996; 395():1-11. PubMed ID: 8895979
    [No Abstract]   [Full Text] [Related]  

  • 19. Reduced p53 dosage associated with mammary tumor metastases in C3(1)/TAG transgenic mice.
    Maroulakou IG; Shibata MA; Jorcyk CL; Chen XX; Green JE
    Mol Carcinog; 1997 Oct; 20(2):168-74. PubMed ID: 9364206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
    Forrester E; Chytil A; Bierie B; Aakre M; Gorska AE; Sharif-Afshar AR; Muller WJ; Moses HL
    Cancer Res; 2005 Mar; 65(6):2296-302. PubMed ID: 15781643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.