These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
153 related articles for article (PubMed ID: 18096051)
1. Improved functional expression of recombinant human ether-a-go-go (hERG) K+ channels by cultivation at reduced temperature. Chen MX; Sandow SL; Doceul V; Chen YH; Harper H; Hamilton B; Meadows HJ; Trezise DJ; Clare JJ BMC Biotechnol; 2007 Dec; 7():93. PubMed ID: 18096051 [TBL] [Abstract][Full Text] [Related]
2. The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o. Diaz GJ; Daniell K; Leitza ST; Martin RL; Su Z; McDermott JS; Cox BF; Gintant GA J Pharmacol Toxicol Methods; 2004; 50(3):187-99. PubMed ID: 15519905 [TBL] [Abstract][Full Text] [Related]
5. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel. Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182 [TBL] [Abstract][Full Text] [Related]
6. Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG. Gillie DJ; Novick SJ; Donovan BT; Payne LA; Townsend C J Pharmacol Toxicol Methods; 2013; 67(1):33-44. PubMed ID: 23103595 [TBL] [Abstract][Full Text] [Related]
7. Evaluation of functional and binding assays in cells expressing either recombinant or endogenous hERG channel. Murphy SM; Palmer M; Poole MF; Padegimas L; Hunady K; Danzig J; Gill S; Gill R; Ting A; Sherf B; Brunden K; Stricker-Krongrad A J Pharmacol Toxicol Methods; 2006; 54(1):42-55. PubMed ID: 16326118 [TBL] [Abstract][Full Text] [Related]
8. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C. Delisle BP; Anderson CL; Balijepalli RC; Anson BD; Kamp TJ; January CT J Biol Chem; 2003 Sep; 278(37):35749-54. PubMed ID: 12837749 [TBL] [Abstract][Full Text] [Related]
9. Molecular determinants of dofetilide block of HERG K+ channels. Ficker E; Jarolimek W; Kiehn J; Baumann A; Brown AM Circ Res; 1998 Feb; 82(3):386-95. PubMed ID: 9486667 [TBL] [Abstract][Full Text] [Related]
10. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG. Rampe D; Roy ML; Dennis A; Brown AM FEBS Lett; 1997 Nov; 417(1):28-32. PubMed ID: 9395068 [TBL] [Abstract][Full Text] [Related]
11. Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride. Zeng H; Penniman JR; Kinose F; Kim D; Trepakova ES; Malik MG; Dech SJ; Balasubramanian B; Salata JJ Assay Drug Dev Technol; 2008 Apr; 6(2):235-41. PubMed ID: 18471077 [TBL] [Abstract][Full Text] [Related]
12. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels. Gordon E; Lozinskaya IM; Lin Z; Semus SF; Blaney FE; Willette RN; Xu X Mol Pharmacol; 2008 Mar; 73(3):639-51. PubMed ID: 18042732 [TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue. Varkevisser R; Houtman MJ; Linder T; de Git KC; Beekman HD; Tidwell RR; Ijzerman AP; Stary-Weinzinger A; Vos MA; van der Heyden MA Br J Pharmacol; 2013 Jul; 169(6):1322-34. PubMed ID: 23586323 [TBL] [Abstract][Full Text] [Related]
15. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects. Zhou Z; Gong Q; January CT J Biol Chem; 1999 Oct; 274(44):31123-6. PubMed ID: 10531299 [TBL] [Abstract][Full Text] [Related]
16. Observations on conducting whole-cell patch clamping of the hERG cardiac K Kang J; Luo Y; Searles M; Rampe D J Appl Toxicol; 2017 Apr; 37(4):445-453. PubMed ID: 27553911 [TBL] [Abstract][Full Text] [Related]
17. [3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel? Finlayson K; Pennington AJ; Kelly JS Eur J Pharmacol; 2001 Feb; 412(3):203-12. PubMed ID: 11166283 [TBL] [Abstract][Full Text] [Related]
18. Strategies to reduce HERG K+ channel blockade. Exploring heteroaromaticity and rigidity in novel pyridine analogues of dofetilide. Carvalho JF; Louvel J; Doornbos ML; Klaasse E; Yu Z; Brussee J; IJzerman AP J Med Chem; 2013 Apr; 56(7):2828-40. PubMed ID: 23473309 [TBL] [Abstract][Full Text] [Related]
19. Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks HT. Bridgland-Taylor MH; Hargreaves AC; Easter A; Orme A; Henthorn DC; Ding M; Davis AM; Small BG; Heapy CG; Abi-Gerges N; Persson F; Jacobson I; Sullivan M; Albertson N; Hammond TG; Sullivan E; Valentin JP; Pollard CE J Pharmacol Toxicol Methods; 2006; 54(2):189-99. PubMed ID: 16563806 [TBL] [Abstract][Full Text] [Related]
20. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels. Ficker E; Jarolimek W; Brown AM Mol Pharmacol; 2001 Dec; 60(6):1343-8. PubMed ID: 11723241 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]