These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 18096386)

  • 41. Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.
    Takahashi T; Haga Y; Sakamoto T; Moriya M; Okamoto O; Nonoshita K; Shibata T; Suga T; Takahashi H; Hirohashi T; Sakuraba A; Gomori A; Iwaasa H; Ohe T; Ishihara A; Ishii Y; Kanatani A; Fukami T
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3511-6. PubMed ID: 19464889
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.
    Schuligoi R; Sedej M; Waldhoer M; Vukoja A; Sturm EM; Lippe IT; Peskar BA; Heinemann A
    J Leukoc Biol; 2009 Jan; 85(1):136-45. PubMed ID: 18835884
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2.
    Buntinx M; Hermans B; Goossens J; Moechars D; Gilissen RA; Doyon J; Boeckx S; Coesemans E; Van Lommen G; Van Wauwe JP
    J Pharmacol Exp Ther; 2008 Oct; 327(1):1-9. PubMed ID: 18599682
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development.
    Wittman MD; Carboni JM; Yang Z; Lee FY; Antman M; Attar R; Balimane P; Chang C; Chen C; Discenza L; Frennesson D; Gottardis MM; Greer A; Hurlburt W; Johnson W; Langley DR; Li A; Li J; Liu P; Mastalerz H; Mathur A; Menard K; Patel K; Sack J; Sang X; Saulnier M; Smith D; Stefanski K; Trainor G; Velaparthi U; Zhang G; Zimmermann K; Vyas DM
    J Med Chem; 2009 Dec; 52(23):7360-3. PubMed ID: 19778024
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Discovery of disubstituted cyclohexanes as a new class of CC chemokine receptor 2 antagonists.
    Cherney RJ; Mo R; Meyer DT; Nelson DJ; Lo YC; Yang G; Scherle PA; Mandlekar S; Wasserman ZR; Jezak H; Solomon KA; Tebben AJ; Carter PH; Decicco CP
    J Med Chem; 2008 Feb; 51(4):721-4. PubMed ID: 18232650
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: a case study with melanocortin-4 receptor agonists.
    Tang W; Stearns RA; Wang RW; Miller RR; Chen Q; Ngui J; Bakshi RK; Nargund RP; Dean DC; Baillie TA
    Xenobiotica; 2008 Nov; 38(11):1437-51. PubMed ID: 18841517
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Inhibitory effects of Schizandrae Fructus on eotaxin secretion in A549 human epithelial cells and eosinophil migration.
    Oh BG; Lee H; Kim Y; Shin M; Hong M; Jung SK; Kim J; Bae H
    Phytomedicine; 2009 Sep; 16(9):814-22. PubMed ID: 19324539
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
    Crosignani S; Page P; Missotten M; Colovray V; Cleva C; Arrighi JF; Atherall J; Macritchie J; Martin T; Humbert Y; Gaudet M; Pupowicz D; Maio M; Pittet PA; Golzio L; Giachetti C; Rocha C; Bernardinelli G; Filinchuk Y; Scheer A; Schwarz MK; Chollet A
    J Med Chem; 2008 Apr; 51(7):2227-43. PubMed ID: 18318469
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Immunoglobulin E-dependent regulation of the CCR3 chemokine receptor by interferon-gamma in atopic asthmatics.
    García-Vega Y; Rodríguez-Perez J; Bermúdez-Badell C; Blanco-Garcés E; Valenzuela-Silva C; López-Saura P; Bello-Rivero I
    Int Arch Allergy Immunol; 2009; 148(3):219-27. PubMed ID: 18849613
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Evidence for a regulatory role of alpha 4-integrins in the maturation of eosinophils generated from the bone marrow in the presence of dexamethasone.
    Gaspar-Elsas MI; Queto T; Vasconcelos Z; Jones CP; Lannes-Vieira J; Xavier-Elsas P
    Clin Exp Allergy; 2009 Aug; 39(8):1187-98. PubMed ID: 19508325
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Design, synthesis and structure-activity relationships of antiproliferative 1,3-disubstituted urea derivatives.
    Li HQ; Zhu TT; Yan T; Luo Y; Zhu HL
    Eur J Med Chem; 2009 Feb; 44(2):453-9. PubMed ID: 18514972
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase.
    Barrow JC; Stauffer SR; Rittle KE; Ngo PL; Yang Z; Selnick HG; Graham SL; Munshi S; McGaughey GB; Holloway MK; Simon AJ; Price EA; Sankaranarayanan S; Colussi D; Tugusheva K; Lai MT; Espeseth AS; Xu M; Huang Q; Wolfe A; Pietrak B; Zuck P; Levorse DA; Hazuda D; Vacca JP
    J Med Chem; 2008 Oct; 51(20):6259-62. PubMed ID: 18811140
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Substituted dipiperidine alcohols as potent CCR2 antagonists.
    Xia M; Hou C; Demong D; Pollack S; Pan M; Brackley J; Singer M; Matheis M; Cavender D; Wachter M
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3562-4. PubMed ID: 18487045
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Design and synthesis of novel CCR3 antagonists.
    Gong L; Hogg JH; Collier J; Wilhelm RS; Soderberg C
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3597-600. PubMed ID: 14505678
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist.
    Antal-Zimanyi I; Bruce MA; Leboulluec KL; Iben LG; Mattson GK; McGovern RT; Hogan JB; Leahy CL; Flowers SC; Stanley JA; Ortiz AA; Poindexter GS
    Eur J Pharmacol; 2008 Aug; 590(1-3):224-32. PubMed ID: 18573246
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators.
    Lum RT; Cheng M; Cristobal CP; Goldfine ID; Evans JL; Keck JG; Macsata RW; Manchem VP; Matsumoto Y; Park SJ; Rao SS; Robinson L; Shi S; Spevak WR; Schow SR
    J Med Chem; 2008 Oct; 51(19):6173-87. PubMed ID: 18788731
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate.
    Westaway SM; Brown SL; Fell SC; Johnson CN; MacPherson DT; Mitchell DJ; Myatt JW; Stanway SJ; Seal JT; Stemp G; Thompson M; Lawless K; McKay F; Muir AI; Barford JM; Cluff C; Mahmood SR; Matthews KL; Mohamed S; Smith B; Stevens AJ; Bolton VJ; Jarvie EM; Sanger GJ
    J Med Chem; 2009 Feb; 52(4):1180-9. PubMed ID: 19191554
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Discovery of bioavailable 4,4-disubstituted piperidines as potent ligands of the chemokine receptor 5 and inhibitors of the human immunodeficiency virus-1.
    Kazmierski WM; Aquino C; Chauder BA; Deanda F; Ferris R; Jones-Hertzog DK; Kenakin T; Koble CS; Watson C; Wheelan P; Yang H; Youngman M
    J Med Chem; 2008 Oct; 51(20):6538-46. PubMed ID: 18811134
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Virulizin induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors.
    Benatar T; Cao MY; Lee Y; Li H; Feng N; Gu X; Lee V; Jin H; Wang M; Der S; Lightfoot J; Wright JA; Young AH
    Cancer Immunol Immunother; 2008 Dec; 57(12):1757-69. PubMed ID: 18351336
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Discovery of a novel series of biphenyl benzoic acid derivatives as highly potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. Part II.
    Imanishi M; Itou S; Washizuka K; Hamashima H; Nakajima Y; Araki T; Tomishima Y; Sakurai M; Matsui S; Imamura E; Ueshima K; Yamamoto T; Yamamoto N; Ishikawa H; Nakano K; Unami N; Hamada K; Matsumura Y; Takamura F; Hattori K
    J Med Chem; 2008 Jul; 51(13):4002-20. PubMed ID: 18553954
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.