290 related articles for article (PubMed ID: 18096673)
21. Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.
Drocourt L; Ourlin JC; Pascussi JM; Maurel P; Vilarem MJ
J Biol Chem; 2002 Jul; 277(28):25125-32. PubMed ID: 11991950
[TBL] [Abstract][Full Text] [Related]
22. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
[TBL] [Abstract][Full Text] [Related]
23. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
Anderson LE; Dring AM; Hamel LD; Stoner MA
Toxicol Lett; 2011 Apr; 202(2):148-54. PubMed ID: 21315811
[TBL] [Abstract][Full Text] [Related]
24. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor.
Wang H; Li H; Moore LB; Johnson MD; Maglich JM; Goodwin B; Ittoop OR; Wisely B; Creech K; Parks DJ; Collins JL; Willson TM; Kalpana GV; Venkatesh M; Xie W; Cho SY; Roboz J; Redinbo M; Moore JT; Mani S
Mol Endocrinol; 2008 Apr; 22(4):838-57. PubMed ID: 18096694
[TBL] [Abstract][Full Text] [Related]
25. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
[TBL] [Abstract][Full Text] [Related]
26. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
[TBL] [Abstract][Full Text] [Related]
27. Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.
Saussele T; Burk O; Blievernicht JK; Klein K; Nussler A; Nussler N; Hengstler JG; Eichelbaum M; Schwab M; Zanger UM
Clin Pharmacol Ther; 2007 Sep; 82(3):265-74. PubMed ID: 17344806
[TBL] [Abstract][Full Text] [Related]
28. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
Roth A; Looser R; Kaufmann M; Meyer UA
Pharmacogenet Genomics; 2008 Apr; 18(4):325-37. PubMed ID: 18334917
[TBL] [Abstract][Full Text] [Related]
29. Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.
Mikamo E; Harada S; Nishikawa J; Nishihara T
Toxicol Appl Pharmacol; 2003 Nov; 193(1):66-72. PubMed ID: 14613717
[TBL] [Abstract][Full Text] [Related]
30. Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.
Nallani SC; Goodwin B; Maglich JM; Buckley DJ; Buckley AR; Desai PB
Drug Metab Dispos; 2003 May; 31(5):681-4. PubMed ID: 12695359
[TBL] [Abstract][Full Text] [Related]
31. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
[TBL] [Abstract][Full Text] [Related]
32. Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics.
LeCluyse EL
Chem Biol Interact; 2001 May; 134(3):283-9. PubMed ID: 11336976
[TBL] [Abstract][Full Text] [Related]
33. Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers.
Faucette SR; Wang H; Hamilton GA; Jolley SL; Gilbert D; Lindley C; Yan B; Negishi M; LeCluyse EL
Drug Metab Dispos; 2004 Mar; 32(3):348-58. PubMed ID: 14977870
[TBL] [Abstract][Full Text] [Related]
34. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
Wyde ME; Bartolucci E; Ueda A; Zhang H; Yan B; Negishi M; You L
Mol Pharmacol; 2003 Aug; 64(2):474-81. PubMed ID: 12869653
[TBL] [Abstract][Full Text] [Related]
35. Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative.
Luo G; Lin J; Fiske WD; Dai R; Yang TJ; Kim S; Sinz M; LeCluyse E; Solon E; Brennan JM; Benedek IH; Jolley S; Gilbert D; Wang L; Lee FW; Gan LS
Drug Metab Dispos; 2003 Sep; 31(9):1170-5. PubMed ID: 12920173
[TBL] [Abstract][Full Text] [Related]
36. Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes.
Shenoy SD; Spencer TA; Mercer-Haines NA; Abdolalipour M; Wurster WL; Runge-Morris M; Kocarek TA
Mol Pharmacol; 2004 May; 65(5):1302-12. PubMed ID: 15102959
[TBL] [Abstract][Full Text] [Related]
37. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
[TBL] [Abstract][Full Text] [Related]
38. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
Fisher CD; Jackson JP; Lickteig AJ; Augustine LM; Cherrington NJ
Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
[TBL] [Abstract][Full Text] [Related]
39. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels.
Chang TK; Bandiera SM; Chen J
Drug Metab Dispos; 2003 Jan; 31(1):7-10. PubMed ID: 12485946
[TBL] [Abstract][Full Text] [Related]
40. Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.
Ma Y; Sachdeva K; Liu J; Song X; Li Y; Yang D; Deng R; Chichester CO; Yan B
Biochem Pharmacol; 2005 May; 69(9):1363-71. PubMed ID: 15826607
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
