BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 18155724)

  • 1. A Flexible peptide tether controls accessibility of a unique C-terminal RNA-binding domain in leucyl-tRNA synthetases.
    Hsu JL; Martinis SA
    J Mol Biol; 2008 Feb; 376(2):482-91. PubMed ID: 18155724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase.
    Nawaz MH; Pang YL; Martinis SA
    J Mol Biol; 2007 Mar; 367(2):384-94. PubMed ID: 17270210
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional divergence of a unique C-terminal domain of leucyl-tRNA synthetase to accommodate its splicing and aminoacylation roles.
    Hsu JL; Rho SB; Vannella KM; Martinis SA
    J Biol Chem; 2006 Aug; 281(32):23075-82. PubMed ID: 16774921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular modeling study of the editing active site of Escherichia coli leucyl-tRNA synthetase: two amino acid binding sites in the editing domain.
    Lee KW; Briggs JM
    Proteins; 2004 Mar; 54(4):693-704. PubMed ID: 14997565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of leucyl-tRNA synthetase from the archaeon Pyrococcus horikoshii reveals a novel editing domain orientation.
    Fukunaga R; Yokoyama S
    J Mol Biol; 2005 Feb; 346(1):57-71. PubMed ID: 15663927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A unique insertion in the CP1 domain of Giardia lamblia leucyl-tRNA synthetase.
    Zhou XL; Yao P; Ruan LL; Zhu B; Luo J; Qu LH; Wang ED
    Biochemistry; 2009 Feb; 48(6):1340-7. PubMed ID: 19170608
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The C-terminal domain of the archaeal leucyl-tRNA synthetase prevents misediting of isoleucyl-tRNA(Ile).
    Fukunaga R; Yokoyama S
    Biochemistry; 2007 May; 46(17):4985-96. PubMed ID: 17407269
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity.
    Huang Q; Zhou XL; Hu QH; Lei HY; Fang ZP; Yao P; Wang ED
    RNA; 2014 Sep; 20(9):1440-50. PubMed ID: 25051973
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional segregation of a predicted "hinge" site within the beta-strand linkers of Escherichia coli leucyl-tRNA synthetase.
    Mascarenhas AP; Martinis SA
    Biochemistry; 2008 Apr; 47(16):4808-16. PubMed ID: 18363380
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing.
    Hu QH; Huang Q; Wang ED
    Nucleic Acids Res; 2013 Feb; 41(3):1859-72. PubMed ID: 23268443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module.
    Yan W; Ye Q; Tan M; Chen X; Eriani G; Wang ED
    J Biol Chem; 2015 May; 290(19):12256-67. PubMed ID: 25817995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A unique insert of leucyl-tRNA synthetase is required for aminoacylation and not amino acid editing.
    Vu MT; Martinis SA
    Biochemistry; 2007 May; 46(17):5170-6. PubMed ID: 17407263
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination.
    Liu Y; Liao J; Zhu B; Wang ED; Ding J
    Biochem J; 2006 Mar; 394(Pt 2):399-407. PubMed ID: 16277600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation.
    Lue SW; Kelley SO
    Biochemistry; 2007 Apr; 46(15):4466-72. PubMed ID: 17378584
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles.
    Seiradake E; Mao W; Hernandez V; Baker SJ; Plattner JJ; Alley MR; Cusack S
    J Mol Biol; 2009 Jul; 390(2):196-207. PubMed ID: 19426743
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity.
    Betha AK; Williams AM; Martinis SA
    Biochemistry; 2007 May; 46(21):6258-67. PubMed ID: 17474713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of alanine-293 replacement on the activity, ATP binding, and editing of Escherichia coli leucyl-tRNA synthetase.
    Chen JF; Li T; Wang ED; Wang YL
    Biochemistry; 2001 Feb; 40(5):1144-9. PubMed ID: 11170439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli leucyl-tRNA synthetase in editing.
    Du X; Wang ED
    Biochemistry; 2002 Aug; 41(34):10623-8. PubMed ID: 12186547
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [An insertion mutant of LeuRS with 116 amino acid residues has full activity].
    Huang Y; Ling C; Li T; Tong GL; Wang ED
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Mar; 35(3):225-9. PubMed ID: 12621546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions.
    Weitzel CS; Li L; Zhang C; Eilts KK; Bretz NM; Gatten AL; Whitaker RJ; Martinis SA
    J Biol Chem; 2020 Apr; 295(14):4563-4576. PubMed ID: 32102848
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.