293 related articles for article (PubMed ID: 18157855)
1. Small-molecule based delivery systems for alkylating antineoplastic compounds.
Bielawski K; Bielawska A
ChemMedChem; 2008 Apr; 3(4):536-42. PubMed ID: 18157855
[TBL] [Abstract][Full Text] [Related]
2. Decreased cytotoxicity and increased antimitotic activity of a proline analogue of chlorambucil as a prodrug susceptible to the action of fibroblast's prolidase.
Bielawska A; Chrzanowski K; Bielawski K; Pałka J
Pharmazie; 2001 Apr; 56(4):290-4. PubMed ID: 11338665
[TBL] [Abstract][Full Text] [Related]
3. Prolidase as a prodrug converting enzyme. III. Synthesis of proline analogues of melphalan and theirs susceptibility to the action of prolidase.
Bielawska A; Bielawski K; Pałka J
Rocz Akad Med Bialymst; 1999; 44():190-9. PubMed ID: 10697434
[TBL] [Abstract][Full Text] [Related]
4. Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells.
Bielawski K; Bielawska A; Sosnowska K; Miltyk W; Winnicka K; Pałka J
Biochem Pharmacol; 2006 Jul; 72(3):320-31. PubMed ID: 16730667
[TBL] [Abstract][Full Text] [Related]
5. Prolidase as a prodrug converting enzyme I. Synthesis of proline analogue of chlorambucil and its susceptibility to the action of prolidase.
Bielawska A; Bielawski K; Pałka J
Rocz Akad Med Bialymst; 1997; 42(1):148-55. PubMed ID: 9581474
[TBL] [Abstract][Full Text] [Related]
6. Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.
Mittal S; Song X; Vig BS; Landowski CP; Kim I; Hilfinger JM; Amidon GL
Mol Pharm; 2005; 2(1):37-46. PubMed ID: 15804176
[TBL] [Abstract][Full Text] [Related]
7. Structure-activity studies of novel amidine analogues of chlorambucil: correlation of cytotoxic activity with DNA-binding affinity and topoisomerase II inhibition.
Bielawska A; Bielawski K; Wołczyński S; Anchim T
Arch Pharm (Weinheim); 2003 Aug; 336(6-7):293-9. PubMed ID: 12953217
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of distamycin analogues - new potential anticancer agents.
Drozdowska D; Rusak M; Miltyk W; Midura-Nowaczek K
Arch Pharm (Weinheim); 2009 Feb; 342(2):87-93. PubMed ID: 19173336
[TBL] [Abstract][Full Text] [Related]
9. Proline analogue of melphalan as a prolidase-convertible pro-drug in breast cancer MCF-7 cells.
Chrzanowski K; Pałka J
Folia Histochem Cytobiol; 2001; 39 Suppl 2():209-11. PubMed ID: 11820612
[TBL] [Abstract][Full Text] [Related]
10. Amidine analogues of melphalan: synthesis, cytotoxic activity, and DNA binding properties.
Bielawska A; Bielawski K; Anchim T
Arch Pharm (Weinheim); 2007 May; 340(5):251-7. PubMed ID: 17458920
[TBL] [Abstract][Full Text] [Related]
11. Prolidase-activated prodrug for cancer chemotherapy cytotoxic activity of proline analogue of chlorambucil in breast cancer MCF-7 cells.
Bielawska A; Bielawski K; Chrzanowski K; Wołczyński S
Farmaco; 2000; 55(11-12):736-41. PubMed ID: 11204951
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase.
Hay MP; Atwell GJ; Wilson WR; Pullen SM; Denny WA
J Med Chem; 2003 Jun; 46(12):2456-66. PubMed ID: 12773049
[TBL] [Abstract][Full Text] [Related]
13. Decreased cytotoxicity and increased antimitotic activity of proline analogue of chlorambucil as a prodrug in breast cancer MCF-7 cells.
Bielawska A; Chrzanowski K; Bielawski K; Pałka J
Acta Pol Pharm; 2000 Nov; 57 Suppl():103-5. PubMed ID: 11293233
[No Abstract] [Full Text] [Related]
14. Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.
Mittal S; Song X; Vig BS; Amidon GL
Pharm Res; 2007 Jul; 24(7):1290-8. PubMed ID: 17377743
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Kim MY; Na Y; Vankayalapati H; Gleason-Guzman M; Hurley LH
J Med Chem; 2003 Jul; 46(14):2958-72. PubMed ID: 12825936
[TBL] [Abstract][Full Text] [Related]
16. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
[TBL] [Abstract][Full Text] [Related]
17. Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells.
Chrzanowski K; Bielawska A; Pałka J
Farmaco; 2003 Nov; 58(11):1113-9. PubMed ID: 14572862
[TBL] [Abstract][Full Text] [Related]
18. Hybrid molecules between distamycin A and active moieties of antitumor agents.
Baraldi PG; Preti D; Fruttarolo F; Tabrizi MA; Romagnoli R
Bioorg Med Chem; 2007 Jan; 15(1):17-35. PubMed ID: 17081759
[TBL] [Abstract][Full Text] [Related]
19. Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
Beria I; Baraldi PG; Cozzi P; Caldarelli M; Geroni C; Marchini S; Mongelli N; Romagnoli R
J Med Chem; 2004 May; 47(10):2611-23. PubMed ID: 15115402
[TBL] [Abstract][Full Text] [Related]
20. Studies of pyrrolo[1,2-alpha]benzimidazolequinone DT-diaphorase substrate activity, topoisomerase II inhibition activity, and DNA reductive alkylation.
Skibo EB; Gordon S; Bess L; Boruah R; Heileman MJ
J Med Chem; 1997 Apr; 40(9):1327-39. PubMed ID: 9135030
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]