157 related articles for article (PubMed ID: 18158200)
1. Angiotensin II--AT1 receptor antagonists: design, synthesis and evaluation of substituted carboxamido benzimidazole derivatives.
Shah DI; Sharma M; Bansal Y; Bansal G; Singh M
Eur J Med Chem; 2008 Sep; 43(9):1808-12. PubMed ID: 18158200
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists.
Wang JL; Zhang J; Zhou ZM; Li ZH; Xue WZ; Xu D; Hao LP; Han XF; Fei F; Liu T; Liang AH
Eur J Med Chem; 2012 Mar; 49():183-90. PubMed ID: 22309912
[TBL] [Abstract][Full Text] [Related]
3. Nonpeptidic angiotensin II AT₁ receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles.
Zhang J; Wang JL; Yu WF; Zhou ZM; Tao WC; Wang YC; Xue WZ; Xu D; Hao LP; Han XF; Fei F; Liu T; Liang AH
Eur J Med Chem; 2013 Nov; 69():44-54. PubMed ID: 24007859
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and pharmacological evaluation of 5-oxo-1,2,4-oxadiazole derivatives as AT1 antagonists with antihypertension activities.
Zhu W; Bao X; Ren H; Liao P; Zhu W; Yan Y; Wang L; Chen Z
Clin Exp Hypertens; 2016; 38(5):435-42. PubMed ID: 27362285
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of AT
Wu Z; Anh NTP; Yan YJ; Xia MB; Wang YH; Qiu Y; Chen ZL
Eur J Med Chem; 2019 Nov; 181():111553. PubMed ID: 31369932
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.
Kaur N; Kaur A; Bansal Y; Shah DI; Bansal G; Singh M
Bioorg Med Chem; 2008 Dec; 16(24):10210-5. PubMed ID: 19013821
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT₁ receptor antagonists.
Zhang J; Wang JL; Zhou ZM; Li ZH; Xue WZ; Xu D; Hao LP; Han XF; Fei F; Liu T; Liang AH
Bioorg Med Chem; 2012 Jul; 20(14):4208-16. PubMed ID: 22727371
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, pharmacological evaluation and in silico ADMET prediction of novel substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonists based on predictive 3D QSAR models.
Vyas VK; Gupta N; Ghate M; Patel S
SAR QSAR Environ Res; 2014; 25(2):117-46. PubMed ID: 24598006
[TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists.
Ismail MA; Barker S; Abou el-Ella DA; Abouzid KA; Toubar RA; Todd MH
J Med Chem; 2006 Mar; 49(5):1526-35. PubMed ID: 16509571
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.
Kim TW; Yoo BW; Lee JK; Kim JH; Lee KT; Chi YH; Lee JY
Bioorg Med Chem Lett; 2012 Feb; 22(4):1649-54. PubMed ID: 22264484
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of new 5-nitro benzimidazole derivatives as AT1 antagonists with anti-hypertension activities.
Zhu W; Da Y; Wu D; Zheng H; Zhu L; Wang L; Yan Y; Chen Z
Bioorg Med Chem; 2014 Apr; 22(7):2294-302. PubMed ID: 24613628
[TBL] [Abstract][Full Text] [Related]
12. Unique "delta lock" structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor.
Ohno K; Amano Y; Kakuta H; Niimi T; Takakura S; Orita M; Miyata K; Sakashita H; Takeuchi M; Komuro I; Higaki J; Horiuchi M; Kim-Mitsuyama S; Mori Y; Morishita R; Yamagishi S
Biochem Biophys Res Commun; 2011 Jan; 404(1):434-7. PubMed ID: 21130741
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring.
Guo XZ; Shi L; Wang R; Liu XX; Li BG; Lu XX
Bioorg Med Chem; 2008 Dec; 16(24):10301-10. PubMed ID: 18976926
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect.
Nie YY; Da YJ; Zheng H; Yang XX; Jia L; Wen CH; Liang LS; Tian J; Chen ZL
Bioorg Med Chem; 2012 Apr; 20(8):2747-61. PubMed ID: 22410249
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and pharmacological evaluation of novel NO-releasing benzimidazole hybrids as potential antihypertensive candidate.
Zhang Y; Xu J; Li Y; Yao H; Wu X
Chem Biol Drug Des; 2015 May; 85(5):541-8. PubMed ID: 25283264
[TBL] [Abstract][Full Text] [Related]
16. Facile and efficient syntheses of a series of N-benzyl and N-biphenylmethyl substituted imidazole derivatives based on (E)-urocanic acid, as angiotensin II AT1 receptor blockers.
Agelis G; Kelaidonis K; Resvani A; Kalavrizioti D; Androutsou ME; Plotas P; Vlahakos D; Koukoulitsa C; Tselios T; Mavromoustakos T; Matsoukas J
Molecules; 2013 Jun; 18(7):7510-32. PubMed ID: 23807577
[TBL] [Abstract][Full Text] [Related]
17. Discovery of novel, potent and low-toxicity angiotensin II receptor type 1 (AT1) blockers: Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazoles with a chiral center.
Han XF; He X; Wang M; Xu D; Hao LP; Liang AH; Zhang J; Zhou ZM
Eur J Med Chem; 2015 Oct; 103():473-87. PubMed ID: 26397395
[TBL] [Abstract][Full Text] [Related]
18. The discovery of new potent non-peptide Angiotensin II AT1 receptor blockers: a concise synthesis, molecular docking studies and biological evaluation of N-substituted 5-butylimidazole derivatives.
Agelis G; Resvani A; Durdagi S; Spyridaki K; Tůmová T; Slaninová J; Giannopoulos P; Vlahakos D; Liapakis G; Mavromoustakos T; Matsoukas J
Eur J Med Chem; 2012 Sep; 55():358-74. PubMed ID: 22889560
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of novel fluoro-substituted benzimidazole derivatives with anti-hypertension activities.
Wu Z; Xia MB; Bertsetseg D; Wang YH; Bao XL; Zhu WB; Tao-Xu ; Chen PR; Tang HS; Yan YJ; Chen ZL
Bioorg Chem; 2020 Aug; 101():104042. PubMed ID: 32650179
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome.
Mizuno CS; Chittiboyina AG; Shah FH; Patny A; Kurtz TW; Pershadsingh HA; Speth RC; Karamyan VT; Carvalho PB; Avery MA
J Med Chem; 2010 Feb; 53(3):1076-85. PubMed ID: 20073471
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
