BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

455 related articles for article (PubMed ID: 18159936)

  • 1. Function-oriented synthesis, step economy, and drug design.
    Wender PA; Verma VA; Paxton TJ; Pillow TH
    Acc Chem Res; 2008 Jan; 41(1):40-9. PubMed ID: 18159936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.
    Feyen F; Cachoux F; Gertsch J; Wartmann M; Altmann KH
    Acc Chem Res; 2008 Jan; 41(1):21-31. PubMed ID: 18159935
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.
    Liu J; Towle MJ; Cheng H; Saxton P; Reardon C; Wu J; Murphy EA; Kuznetsov G; Johannes CW; Tremblay MR; Zhao H; Pesant M; Fang FG; Vermeulen MW; Gallagher BM; Littlefield BA
    Anticancer Res; 2007; 27(3B):1509-18. PubMed ID: 17595769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads.
    Ojima I
    Acc Chem Res; 2008 Jan; 41(1):108-19. PubMed ID: 17663526
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin.
    Tannert R; Milroy LG; Ellinger B; Hu TS; Arndt HD; Waldmann H
    J Am Chem Soc; 2010 Mar; 132(9):3063-77. PubMed ID: 20148556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue.
    Wender PA; Hilinski MK; Soldermann N; Mooberry SL
    Org Lett; 2006 Mar; 8(7):1507-10. PubMed ID: 16562928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain.
    Paterson I; Menche D; Håkansson AE; Longstaff A; Wong D; Barasoain I; Buey RM; Díaz JF
    Bioorg Med Chem Lett; 2005 May; 15(9):2243-7. PubMed ID: 15837302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries.
    Shang S; Tan DS
    Curr Opin Chem Biol; 2005 Jun; 9(3):248-58. PubMed ID: 15939326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Function through synthesis-informed design.
    Wender PA; Quiroz RV; Stevens MC
    Acc Chem Res; 2015 Mar; 48(3):752-60. PubMed ID: 25742599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: development of a synthetically accessible protein kinase C activator with bryostatin-like activity.
    Nakagawa Y; Yanagita RC; Hamada N; Murakami A; Takahashi H; Saito N; Nagai H; Irie K
    J Am Chem Soc; 2009 Jun; 131(22):7573-9. PubMed ID: 19449873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Natural product-like libraries based on non-aromatic, polycyclic motifs.
    Messer R; Fuhrer CA; Häner R
    Curr Opin Chem Biol; 2005 Jun; 9(3):259-65. PubMed ID: 15939327
    [TBL] [Abstract][Full Text] [Related]  

  • 12. From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries.
    Breinbauer R; Vetter IR; Waldmann H
    Angew Chem Int Ed Engl; 2002 Aug; 41(16):2879-90. PubMed ID: 12203413
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Current developments in the discovery and design of new drug candidates from plant natural product leads.
    Lee KH
    J Nat Prod; 2004 Feb; 67(2):273-83. PubMed ID: 14987069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological activity of cell-penetrating peptide-modified octreotide analogs.
    Xie W; Liu J; Qiu M; Yuan J; Xu A
    J Pept Sci; 2010 Feb; 16(2):105-9. PubMed ID: 20014325
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of natural product chemistry in drug discovery.
    Butler MS
    J Nat Prod; 2004 Dec; 67(12):2141-53. PubMed ID: 15620274
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Natural product-like chemical space: search for chemical dissectors of macromolecular interactions.
    Reayi A; Arya P
    Curr Opin Chem Biol; 2005 Jun; 9(3):240-7. PubMed ID: 15939325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nanoparticles for drug delivery in cancer treatment.
    Haley B; Frenkel E
    Urol Oncol; 2008; 26(1):57-64. PubMed ID: 18190833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformationally restricted analogues of psorospermin: design, synthesis, and bioactivity of natural-product-related bisfuranoxanthones.
    Heald RA; Dexheimer TS; Vankayalapati H; Siddiqui-Jain A; Szabo LZ; Gleason-Guzman MC; Hurley LH
    J Med Chem; 2005 Apr; 48(8):2993-3004. PubMed ID: 15828838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Designed TPR modules as novel anticancer agents.
    Cortajarena AL; Yi F; Regan L
    ACS Chem Biol; 2008 Mar; 3(3):161-6. PubMed ID: 18355005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Natural product hybrids as new leads for drug discovery.
    Tietze LF; Bell HP; Chandrasekhar S
    Angew Chem Int Ed Engl; 2003 Sep; 42(34):3996-4028. PubMed ID: 12973759
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.