These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

413 related articles for article (PubMed ID: 18164198)

  • 21. Synthesis and biological evaluation of (±)-benzhydrol derivatives as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ma XD; Zhang X; Yang SQ; Dai HF; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
    Bioorg Med Chem; 2011 Aug; 19(16):4704-9. PubMed ID: 21788138
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues.
    Wang Y; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Chem Biodivers; 2008 Jan; 5(1):168-76. PubMed ID: 18205120
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors.
    Xu B; Sun Y; Guo Y; Cao Y; Yu T
    Bioorg Med Chem; 2009 Apr; 17(7):2767-74. PubMed ID: 19269831
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    J Med Chem; 2007 Apr; 50(8):1778-86. PubMed ID: 17381078
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
    Shi J; McAtee JJ; Schlueter Wirtz S; Tharnish P; Juodawlkis A; Liotta DC; Schinazi RF
    J Med Chem; 1999 Mar; 42(5):859-67. PubMed ID: 10072683
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.
    Mugnaini C; Alongi M; Togninelli A; Gevariya H; Brizzi A; Manetti F; Bernardini C; Angeli L; Tafi A; Bellucci L; Corelli F; Massa S; Maga G; Samuele A; Facchini M; Clotet-Codina I; Armand-Ugón M; Esté JA; Botta M
    J Med Chem; 2007 Dec; 50(26):6580-95. PubMed ID: 18052319
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
    Fattorusso C; Gemma S; Butini S; Huleatt P; Catalanotti B; Persico M; De Angelis M; Fiorini I; Nacci V; Ramunno A; Rodriquez M; Greco G; Novellino E; Bergamini A; Marini S; Coletta M; Maga G; Spadari S; Campiani G
    J Med Chem; 2005 Nov; 48(23):7153-65. PubMed ID: 16279773
    [TBL] [Abstract][Full Text] [Related]  

  • 28. D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance.
    Wang J; Jin Y; Rapp KL; Schinazi RF; Chu CK
    J Med Chem; 2007 Apr; 50(8):1828-39. PubMed ID: 17373782
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT.
    Barreca ML; Rao A; De Luca L; Zappalà M; Monforte AM; Maga G; Pannecouque C; Balzarini J; De Clercq E; Chimirri A; Monforte P
    J Med Chem; 2005 May; 48(9):3433-7. PubMed ID: 15857150
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and anti-HIV activity evaluation of 1-[(alkenyl or alkynyl or alkyloxy)methyl]-5-alkyl-6-(1-naphthoyl)-2,4-pyrimidinediones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; Xie B; De Clercq E; Balzarini J; Pannecouque C
    Eur J Med Chem; 2007 Feb; 42(2):198-204. PubMed ID: 17095124
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides: novel inhibitors of reverse transcriptase.
    Chiacchio U; Balestrieri E; Macchi B; Iannazzo D; Piperno A; Rescifina A; Romeo R; Saglimbeni M; Sciortino MT; Valveri V; Mastino A; Romeo G
    J Med Chem; 2005 Mar; 48(5):1389-94. PubMed ID: 15743182
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
    Su DS; Lim JJ; Tinney E; Wan BL; Young MB; Anderson KD; Rudd D; Munshi V; Bahnck C; Felock PJ; Lu M; Lai MT; Touch S; Moyer G; Distefano DJ; Flynn JA; Liang Y; Sanchez R; Prasad S; Yan Y; Perlow-Poehnelt R; Torrent M; Miller M; Vacca JP; Williams TM; Anthony NJ
    Bioorg Med Chem Lett; 2009 Sep; 19(17):5119-23. PubMed ID: 19631528
    [TBL] [Abstract][Full Text] [Related]  

  • 33. New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.
    Le Van K; Cauvin C; de Walque S; Georges B; Boland S; Martinelli V; Demonté D; Durant F; Hevesi L; Van Lint C
    J Med Chem; 2009 Jun; 52(12):3636-43. PubMed ID: 19469474
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and biological evaluation of novel 2-arylalkylthio-4-amino-6-benzyl pyrimidines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Qin H; Liu C; Zhang J; Guo Y; Zhang S; Zhang Z; Wang X; Zhang L; Liu J
    Bioorg Med Chem Lett; 2010 May; 20(9):3003-5. PubMed ID: 20347295
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and anti-HIV properties of novel 6-phenylselenenyl-5-propyluracils.
    Miazga A; Felczak K; Siwecka MA; Lipniacki A; Piasek A; Kulikowski T
    Acta Biochim Pol; 2007; 54(4):863-8. PubMed ID: 18066398
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Wang YP; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Med Chem; 2008 Apr; 16(7):3887-94. PubMed ID: 18267363
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
    Mackman RL; Zhang L; Prasad V; Boojamra CG; Douglas J; Grant D; Hui H; Kim CU; Laflamme G; Parrish J; Stoycheva AD; Swaminathan S; Wang K; Cihlar T
    Bioorg Med Chem; 2007 Aug; 15(16):5519-28. PubMed ID: 17562366
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.
    Zhan P; Liu X; Fang Z; Pannecouque C; De Clercq E
    Bioorg Med Chem; 2009 Sep; 17(17):6374-9. PubMed ID: 19647440
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Difluoromethylbenzoxazole pyrimidine thioether derivatives: a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Boyer J; Arnoult E; Médebielle M; Guillemont J; Unge J; Jochmans D
    J Med Chem; 2011 Dec; 54(23):7974-85. PubMed ID: 22017513
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design and synthesis of α-carboxy nucleoside phosphonate analogues and evaluation as HIV-1 reverse transcriptase-targeting agents.
    Keane SJ; Ford A; Mullins ND; Maguire NM; Legigan T; Balzarini J; Maguire AR
    J Org Chem; 2015 Mar; 80(5):2479-93. PubMed ID: 25532055
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.