These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

838 related articles for article (PubMed ID: 18165233)

  • 1. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.
    Laviad EL; Albee L; Pankova-Kholmyansky I; Epstein S; Park H; Merrill AH; Futerman AH
    J Biol Chem; 2008 Feb; 283(9):5677-84. PubMed ID: 18165233
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.
    Pewzner-Jung Y; Park H; Laviad EL; Silva LC; Lahiri S; Stiban J; Erez-Roman R; Brügger B; Sachsenheimer T; Wieland F; Prieto M; Merrill AH; Futerman AH
    J Biol Chem; 2010 Apr; 285(14):10902-10. PubMed ID: 20110363
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Eleven residues determine the acyl chain specificity of ceramide synthases.
    Tidhar R; Zelnik ID; Volpert G; Ben-Dor S; Kelly S; Merrill AH; Futerman AH
    J Biol Chem; 2018 Jun; 293(25):9912-9921. PubMed ID: 29632068
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ceramide metabolism in mouse tissue.
    Schiffmann S; Birod K; Männich J; Eberle M; Wegner MS; Wanger R; Hartmann D; Ferreiros N; Geisslinger G; Grösch S
    Int J Biochem Cell Biol; 2013 Aug; 45(8):1886-94. PubMed ID: 23792024
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of ceramide synthase activity via dimerization.
    Laviad EL; Kelly S; Merrill AH; Futerman AH
    J Biol Chem; 2012 Jun; 287(25):21025-33. PubMed ID: 22539345
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.
    Sassa T; Hirayama T; Kihara A
    J Biol Chem; 2016 Apr; 291(14):7477-87. PubMed ID: 26887952
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and Disease.
    Richardson WJ; Humphrey SB; Sears SM; Hoffman NA; Orwick AJ; Doll MA; Doll CL; Xia C; Hernandez-Corbacho M; Snider JM; Obeid LM; Hannun YA; Snider AJ; Siskind LJ
    Mol Pharmacol; 2024 Feb; 105(3):131-143. PubMed ID: 38164625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance.
    Ponnusamy S; Meyers-Needham M; Senkal CE; Saddoughi SA; Sentelle D; Selvam SP; Salas A; Ogretmen B
    Future Oncol; 2010 Oct; 6(10):1603-24. PubMed ID: 21062159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.
    Berdyshev EV; Gorshkova I; Skobeleva A; Bittman R; Lu X; Dudek SM; Mirzapoiazova T; Garcia JG; Natarajan V
    J Biol Chem; 2009 Feb; 284(9):5467-77. PubMed ID: 19119142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway.
    Taniguchi M; Kitatani K; Kondo T; Hashimoto-Nishimura M; Asano S; Hayashi A; Mitsutake S; Igarashi Y; Umehara H; Takeya H; Kigawa J; Okazaki T
    J Biol Chem; 2012 Nov; 287(47):39898-910. PubMed ID: 23035115
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.
    Osawa Y; Uchinami H; Bielawski J; Schwabe RF; Hannun YA; Brenner DA
    J Biol Chem; 2005 Jul; 280(30):27879-87. PubMed ID: 15946935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.
    Kihara A; Mitsutake S; Mizutani Y; Igarashi Y
    Prog Lipid Res; 2007 Mar; 46(2):126-44. PubMed ID: 17449104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain.
    Tidhar R; Ben-Dor S; Wang E; Kelly S; Merrill AH; Futerman AH
    J Biol Chem; 2012 Jan; 287(5):3197-206. PubMed ID: 22144673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An overview of sphingolipid metabolism: from synthesis to breakdown.
    Gault CR; Obeid LM; Hannun YA
    Adv Exp Med Biol; 2010; 688():1-23. PubMed ID: 20919643
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide.
    Miller M; Rosenthal P; Beppu A; Gordillo R; Broide DH
    J Allergy Clin Immunol; 2017 Apr; 139(4):1373-1376.e4. PubMed ID: 27826095
    [No Abstract]   [Full Text] [Related]  

  • 16. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea.
    Brüggen B; Kremser C; Bickert A; Ebel P; Vom Dorp K; Schultz K; Dörmann P; Willecke K; Dedek K
    Eur J Neurosci; 2016 Jul; 44(1):1700-13. PubMed ID: 27086873
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.
    Dai L; Trillo-Tinoco J; Bai A; Chen Y; Bielawski J; Del Valle L; Smith CD; Ochoa AC; Qin Z; Parsons C
    Oncotarget; 2015 Sep; 6(27):24246-60. PubMed ID: 26327294
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism.
    Mullen TD; Spassieva S; Jenkins RW; Kitatani K; Bielawski J; Hannun YA; Obeid LM
    J Lipid Res; 2011 Jan; 52(1):68-77. PubMed ID: 20940143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of altered sphingolipid acyl chain length on various disease models.
    Park WJ; Park JW
    Biol Chem; 2015 Jun; 396(6-7):693-705. PubMed ID: 25720066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.
    Ferreira NS; Engelsby H; Neess D; Kelly SL; Volpert G; Merrill AH; Futerman AH; Færgeman NJ
    J Biol Chem; 2017 May; 292(18):7588-7597. PubMed ID: 28320857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.