193 related articles for article (PubMed ID: 18165239)
1. Acetylation-dependent ADP-ribosylation by Trypanosoma brucei Sir2.
Kowieski TM; Lee S; Denu JM
J Biol Chem; 2008 Feb; 283(9):5317-26. PubMed ID: 18165239
[TBL] [Abstract][Full Text] [Related]
2. A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei.
García-Salcedo JA; Gijón P; Nolan DP; Tebabi P; Pays E
EMBO J; 2003 Nov; 22(21):5851-62. PubMed ID: 14592982
[TBL] [Abstract][Full Text] [Related]
3. Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.
Borra MT; Langer MR; Slama JT; Denu JM
Biochemistry; 2004 Aug; 43(30):9877-87. PubMed ID: 15274642
[TBL] [Abstract][Full Text] [Related]
4. Side chain specificity of ADP-ribosylation by a sirtuin.
Fahie K; Hu P; Swatkoski S; Cotter RJ; Zhang Y; Wolberger C
FEBS J; 2009 Dec; 276(23):7159-76. PubMed ID: 19895577
[TBL] [Abstract][Full Text] [Related]
5. Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product.
Tanny JC; Moazed D
Proc Natl Acad Sci U S A; 2001 Jan; 98(2):415-20. PubMed ID: 11134535
[TBL] [Abstract][Full Text] [Related]
6. Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.
Du J; Jiang H; Lin H
Biochemistry; 2009 Apr; 48(13):2878-90. PubMed ID: 19220062
[TBL] [Abstract][Full Text] [Related]
7. SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates.
Sauve AA; Schramm VL
Curr Med Chem; 2004 Apr; 11(7):807-26. PubMed ID: 15078167
[TBL] [Abstract][Full Text] [Related]
8. Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases.
Khan AN; Lewis PN
J Biol Chem; 2006 Apr; 281(17):11702-11. PubMed ID: 16520376
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Zhao K; Harshaw R; Chai X; Marmorstein R
Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8563-8. PubMed ID: 15150415
[TBL] [Abstract][Full Text] [Related]
10. Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase.
French JB; Cen Y; Sauve AA
Biochemistry; 2008 Sep; 47(38):10227-39. PubMed ID: 18729382
[TBL] [Abstract][Full Text] [Related]
11. Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity.
Merrick CJ; Duraisingh MT
Eukaryot Cell; 2007 Nov; 6(11):2081-91. PubMed ID: 17827348
[TBL] [Abstract][Full Text] [Related]
12. Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose.
Tanner KG; Landry J; Sternglanz R; Denu JM
Proc Natl Acad Sci U S A; 2000 Dec; 97(26):14178-82. PubMed ID: 11106374
[TBL] [Abstract][Full Text] [Related]
13. Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions.
Sauve AA; Celic I; Avalos J; Deng H; Boeke JD; Schramm VL
Biochemistry; 2001 Dec; 40(51):15456-63. PubMed ID: 11747420
[TBL] [Abstract][Full Text] [Related]
14. Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
Smith BC; Denu JM
Biochemistry; 2006 Jan; 45(1):272-82. PubMed ID: 16388603
[TBL] [Abstract][Full Text] [Related]
15. Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases.
Jackson MD; Schmidt MT; Oppenheimer NJ; Denu JM
J Biol Chem; 2003 Dec; 278(51):50985-98. PubMed ID: 14522996
[TBL] [Abstract][Full Text] [Related]
16. Structural basis for the NAD-dependent deacetylase mechanism of Sir2.
Chang JH; Kim HC; Hwang KY; Lee JW; Jackson SP; Bell SD; Cho Y
J Biol Chem; 2002 Sep; 277(37):34489-98. PubMed ID: 12091395
[TBL] [Abstract][Full Text] [Related]
17. Structure and biochemical functions of SIRT6.
Pan PW; Feldman JL; Devries MK; Dong A; Edwards AM; Denu JM
J Biol Chem; 2011 Apr; 286(16):14575-87. PubMed ID: 21362626
[TBL] [Abstract][Full Text] [Related]
18. Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases.
Jackson MD; Denu JM
J Biol Chem; 2002 May; 277(21):18535-44. PubMed ID: 11893743
[TBL] [Abstract][Full Text] [Related]
19. Role of NAD(+) in the deacetylase activity of the SIR2-like proteins.
Landry J; Slama JT; Sternglanz R
Biochem Biophys Res Commun; 2000 Nov; 278(3):685-90. PubMed ID: 11095969
[TBL] [Abstract][Full Text] [Related]
20. Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.
Borra MT; O'Neill FJ; Jackson MD; Marshall B; Verdin E; Foltz KR; Denu JM
J Biol Chem; 2002 Apr; 277(15):12632-41. PubMed ID: 11812793
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]