BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 18166348)

  • 1. Functional characterization of the novel APC N1026S variant associated with attenuated familial adenomatous polyposis.
    Menéndez M; González S; Obrador-Hevia A; Domínguez A; Pujol MJ; Valls J; Canela N; Blanco I; Torres A; Pineda-Lucena A; Moreno V; Bachs O; Capellá G
    Gastroenterology; 2008 Jan; 134(1):56-64. PubMed ID: 18166348
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas.
    Venesio T; Balsamo A; Scordamaglia A; Bertolaso M; Arrigoni A; Sprujevnik T; Rossini FP; Risio M
    Mod Pathol; 2003 Jan; 16(1):57-65. PubMed ID: 12527714
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM; Brauburger K; Behrens J; Schneikert J
    Oncogene; 2010 Mar; 29(11):1663-71. PubMed ID: 19966865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.
    Kohler EM; Chandra SH; Behrens J; Schneikert J
    Hum Mol Genet; 2009 Jan; 18(2):213-26. PubMed ID: 18854359
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A; Kullmann F
    Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H; Sutter C; Kadmon M; Otto HF; Von Knebel-Doeberitz M; Gebert J; Helmke BM
    Genes Chromosomes Cancer; 2004 Oct; 41(2):93-8. PubMed ID: 15287021
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene.
    Aretz S; Uhlhaas S; Sun Y; Pagenstecher C; Mangold E; Caspari R; Möslein G; Schulmann K; Propping P; Friedl W
    Hum Mutat; 2004 Nov; 24(5):370-80. PubMed ID: 15459959
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis.
    Dihlmann S; Gebert J; Siermann A; Herfarth C; von Knebel Doeberitz M
    Cancer Res; 1999 Apr; 59(8):1857-60. PubMed ID: 10213492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
    Nielsen M; Hes FJ; Nagengast FM; Weiss MM; Mathus-Vliegen EM; Morreau H; Breuning MH; Wijnen JT; Tops CM; Vasen HF
    Clin Genet; 2007 May; 71(5):427-33. PubMed ID: 17489848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [From gene to disease; the APC gene and familial adenomatous polyposis coli].
    van der Luijt RB; Tops CM; Vasen HF
    Ned Tijdschr Geneeskd; 2000 Oct; 144(42):2007-9. PubMed ID: 11072519
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel findings in Swedish patients with MYH-associated polyposis: mutation detection and clinical characterization.
    Kanter-Smoler G; Björk J; Fritzell K; Engwall Y; Hallberg B; Karlsson G; Grönberg H; Karlsson P; Wallgren A; Wahlström J; Hultcrantz R; Nordling M
    Clin Gastroenterol Hepatol; 2006 Apr; 4(4):499-506. PubMed ID: 16616356
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced expression of cyclooxygenase-2 and nuclear beta-catenin are related to mutations in the APC gene in human colorectal cancer.
    Dimberg J; Hugander A; Sirsjö A; Söderkvist P
    Anticancer Res; 2001; 21(2A):911-5. PubMed ID: 11396184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis.
    Ficari F; Cama A; Valanzano R; Curia MC; Palmirotta R; Aceto G; Esposito DL; Crognale S; Lombardi A; Messerini L; Mariani-Costantini R; Tonelli F; Battista P
    Br J Cancer; 2000 Jan; 82(2):348-53. PubMed ID: 10646887
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Germline mutation of adenomatous polyposis coli gene in Chinese patients with familial adenomatous polyposis].
    Wang TT; Chen SQ; Zhang XM
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2008 Apr; 25(2):199-202. PubMed ID: 18393246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients.
    Inomata M; Ochiai A; Akimoto S; Kitano S; Hirohashi S
    Cancer Res; 1996 May; 56(9):2213-7. PubMed ID: 8616874
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.
    Tomita H; Yamada Y; Oyama T; Hata K; Hirose Y; Hara A; Kunisada T; Sugiyama Y; Adachi Y; Linhart H; Mori H
    Cancer Res; 2007 May; 67(9):4079-87. PubMed ID: 17483318
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of intestinal polyposis with reduced angiogenesis in ApcMin/+ mice due to decreases in c-Myc expression.
    Yekkala K; Baudino TA
    Mol Cancer Res; 2007 Dec; 5(12):1296-303. PubMed ID: 18171987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Gaujoux S; Pinson S; Gimenez-Roqueplo AP; Amar L; Ragazzon B; Launay P; Meatchi T; Libé R; Bertagna X; Audebourg A; Zucman-Rossi J; Tissier F; Bertherat J
    Clin Cancer Res; 2010 Nov; 16(21):5133-41. PubMed ID: 20978149
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Colorectal cancer and genetic alterations in the Wnt pathway.
    Segditsas S; Tomlinson I
    Oncogene; 2006 Dec; 25(57):7531-7. PubMed ID: 17143297
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neurotensin receptor 1 gene activation by the Tcf/beta-catenin pathway is an early event in human colonic adenomas.
    Souazé F; Viardot-Foucault V; Roullet N; Toy-Miou-Leong M; Gompel A; Bruyneel E; Comperat E; Faux MC; Mareel M; Rostène W; Fléjou JF; Gespach C; Forgez P
    Carcinogenesis; 2006 Apr; 27(4):708-16. PubMed ID: 16299383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.