These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

425 related articles for article (PubMed ID: 18172022)

  • 1. Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae.
    Soper JH; Roy S; Stieber A; Lee E; Wilson RB; Trojanowski JQ; Burd CG; Lee VM
    Mol Biol Cell; 2008 Mar; 19(3):1093-103. PubMed ID: 18172022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.
    Gitler AD; Bevis BJ; Shorter J; Strathearn KE; Hamamichi S; Su LJ; Caldwell KA; Caldwell GA; Rochet JC; McCaffery JM; Barlowe C; Lindquist S
    Proc Natl Acad Sci U S A; 2008 Jan; 105(1):145-50. PubMed ID: 18162536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells.
    Luk KC; Song C; O'Brien P; Stieber A; Branch JR; Brunden KR; Trojanowski JQ; Lee VM
    Proc Natl Acad Sci U S A; 2009 Nov; 106(47):20051-6. PubMed ID: 19892735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alpha-Synuclein and the Endolysosomal System in Parkinson's Disease: Guilty by Association.
    Teixeira M; Sheta R; Idi W; Oueslati A
    Biomolecules; 2021 Sep; 11(9):. PubMed ID: 34572546
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations.
    Sahay S; Ghosh D; Singh PK; Maji SK
    Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.
    Cooper AA; Gitler AD; Cashikar A; Haynes CM; Hill KJ; Bhullar B; Liu K; Xu K; Strathearn KE; Liu F; Cao S; Caldwell KA; Caldwell GA; Marsischky G; Kolodner RD; Labaer J; Rochet JC; Bonini NM; Lindquist S
    Science; 2006 Jul; 313(5785):324-8. PubMed ID: 16794039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.
    Mahul-Mellier AL; Burtscher J; Maharjan N; Weerens L; Croisier M; Kuttler F; Leleu M; Knott GW; Lashuel HA
    Proc Natl Acad Sci U S A; 2020 Mar; 117(9):4971-4982. PubMed ID: 32075919
    [TBL] [Abstract][Full Text] [Related]  

  • 8. α-Synuclein misfolding and aggregation: Implications in Parkinson's disease pathogenesis.
    Mehra S; Sahay S; Maji SK
    Biochim Biophys Acta Proteins Proteom; 2019 Oct; 1867(10):890-908. PubMed ID: 30853581
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion.
    von Einem B; Eschbach J; Kiechle M; Wahler A; Thal DR; McLean PJ; Weishaupt JH; Ludolph AC; von Arnim CAF; Danzer KM
    Aging (Albany NY); 2017 Jul; 9(7):1677-1697. PubMed ID: 28722658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis.
    Soper JH; Kehm V; Burd CG; Bankaitis VA; Lee VM
    J Mol Neurosci; 2011 Mar; 43(3):391-405. PubMed ID: 20890676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes.
    Volpicelli-Daley LA; Gamble KL; Schultheiss CE; Riddle DM; West AB; Lee VM
    Mol Biol Cell; 2014 Dec; 25(25):4010-23. PubMed ID: 25298402
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies.
    Marvian AT; Koss DJ; Aliakbari F; Morshedi D; Outeiro TF
    J Neurochem; 2019 Sep; 150(5):535-565. PubMed ID: 31004503
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative Analysis of the Conformation, Aggregation, Interaction, and Fibril Morphologies of Human α-, β-, and γ-Synuclein Proteins.
    Jain MK; Singh P; Roy S; Bhat R
    Biochemistry; 2018 Jul; 57(26):3830-3848. PubMed ID: 29851342
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of protein interfaces between α-synuclein, the principal component of Lewy bodies in Parkinson disease, and the molecular chaperones human Hsc70 and the yeast Ssa1p.
    Redeker V; Pemberton S; Bienvenut W; Bousset L; Melki R
    J Biol Chem; 2012 Sep; 287(39):32630-9. PubMed ID: 22843682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
    Paleologou KE; Oueslati A; Shakked G; Rospigliosi CC; Kim HY; Lamberto GR; Fernandez CO; Schmid A; Chegini F; Gai WP; Chiappe D; Moniatte M; Schneider BL; Aebischer P; Eliezer D; Zweckstetter M; Masliah E; Lashuel HA
    J Neurosci; 2010 Mar; 30(9):3184-98. PubMed ID: 20203178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-synuclein aggregation and its modulation.
    Ghosh D; Mehra S; Sahay S; Singh PK; Maji SK
    Int J Biol Macromol; 2017 Jul; 100():37-54. PubMed ID: 27737778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-Synuclein: membrane interactions and toxicity in Parkinson's disease.
    Auluck PK; Caraveo G; Lindquist S
    Annu Rev Cell Dev Biol; 2010; 26():211-33. PubMed ID: 20500090
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication.
    Xie YY; Zhou CJ; Zhou ZR; Hong J; Che MX; Fu QS; Song AX; Lin DH; Hu HY
    FASEB J; 2010 Jan; 24(1):196-205. PubMed ID: 19762560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.
    Su LJ; Auluck PK; Outeiro TF; Yeger-Lotem E; Kritzer JA; Tardiff DF; Strathearn KE; Liu F; Cao S; Hamamichi S; Hill KJ; Caldwell KA; Bell GW; Fraenkel E; Cooper AA; Caldwell GA; McCaffery JM; Rochet JC; Lindquist S
    Dis Model Mech; 2010; 3(3-4):194-208. PubMed ID: 20038714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
    Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
    Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.