204 related articles for article (PubMed ID: 18172616)
1. Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.
Sugatani J; Mizushima K; Osabe M; Yamakawa K; Kakizaki S; Takagi H; Mori M; Ikari A; Miwa M
Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun; 377(4-6):597-605. PubMed ID: 18172616
[TBL] [Abstract][Full Text] [Related]
2. Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver.
Li Y; Buckley D; Wang S; Klaassen CD; Zhong XB
Drug Metab Dispos; 2009 Sep; 37(9):1978-86. PubMed ID: 19541828
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
Sugatani J; Nishitani S; Yamakawa K; Yoshinari K; Sueyoshi T; Negishi M; Miwa M
Mol Pharmacol; 2005 Mar; 67(3):845-55. PubMed ID: 15557560
[TBL] [Abstract][Full Text] [Related]
4. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
[TBL] [Abstract][Full Text] [Related]
5. Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
Sugatani J; Uchida T; Kurosawa M; Yamaguchi M; Yamazaki Y; Ikari A; Miwa M
Drug Metab Dispos; 2012 Oct; 40(10):2031-40. PubMed ID: 22829544
[TBL] [Abstract][Full Text] [Related]
6. Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor.
Sugatani J; Sueyoshi T; Negishi M; Miwa M
Methods Enzymol; 2005; 400():92-104. PubMed ID: 16399345
[TBL] [Abstract][Full Text] [Related]
7. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
Buckley DB; Klaassen CD
Drug Metab Dispos; 2009 Apr; 37(4):847-56. PubMed ID: 19144771
[TBL] [Abstract][Full Text] [Related]
8. Function, genetic polymorphism, and transcriptional regulation of human UDP-glucuronosyltransferase (UGT) 1A1.
Sugatani J
Drug Metab Pharmacokinet; 2013; 28(2):83-92. PubMed ID: 23089802
[TBL] [Abstract][Full Text] [Related]
9. Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity.
Kitagawa C; Ando M; Ando Y; Sekido Y; Wakai K; Imaizumi K; Shimokata K; Hasegawa Y
Pharmacogenet Genomics; 2005 Jan; 15(1):35-41. PubMed ID: 15864124
[TBL] [Abstract][Full Text] [Related]
10. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C; Daujat-Chavanieu M; Pascussi JM; Pichard-Garcia L; Balaguer P; Fabre JM; Vilarem MJ; Maurel P; Gerbal-Chaloin S
Mol Pharmacol; 2006 Jul; 70(1):329-39. PubMed ID: 16608920
[TBL] [Abstract][Full Text] [Related]
11. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
[TBL] [Abstract][Full Text] [Related]
12. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
[TBL] [Abstract][Full Text] [Related]
13. Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia.
Sugatani J; Yamakawa K; Yoshinari K; Machida T; Takagi H; Mori M; Kakizaki S; Sueyoshi T; Negishi M; Miwa M
Biochem Biophys Res Commun; 2002 Mar; 292(2):492-7. PubMed ID: 11906189
[TBL] [Abstract][Full Text] [Related]
14. The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.
Sugatani J; Kojima H; Ueda A; Kakizaki S; Yoshinari K; Gong QH; Owens IS; Negishi M; Sueyoshi T
Hepatology; 2001 May; 33(5):1232-8. PubMed ID: 11343253
[TBL] [Abstract][Full Text] [Related]
15. Disruption of HNF1Ī± binding site causes inherited severe unconjugated hyperbilirubinemia.
van Dijk R; Mayayo-Peralta I; Aronson SJ; Kattentidt-Mouravieva AA; van der Mark VA; de Knegt R; Oruc N; Beuers U; Bosma PJ
J Hepatol; 2015 Dec; 63(6):1525-9. PubMed ID: 26220753
[TBL] [Abstract][Full Text] [Related]
16. Induction of human UGT1A1 by a complex of dexamethasone-GR dependent on proximal site and independent of PBREM.
Kuno T; Togawa H; Mizutani T
Mol Biol Rep; 2008 Sep; 35(3):361-7. PubMed ID: 17530442
[TBL] [Abstract][Full Text] [Related]
17. Activation of the mouse TATA-less and human TATA-containing UDP-glucuronosyltransferase 1A1 promoters by hepatocyte nuclear factor 1.
Bernard P; Goudonnet H; Artur Y; Desvergne B; Wahli W
Mol Pharmacol; 1999 Sep; 56(3):526-36. PubMed ID: 10462540
[TBL] [Abstract][Full Text] [Related]
18. Cell Cycle and Apoptosis Regulator 1, CCAR1, Regulates Enhancer-Dependent Nuclear Receptor CAR Transactivation.
Kanno Y; Zhao S; Yamashita N; Saito N; Ujiie A; Iijima R; Kikawa N; Nemoto K; Inouye Y
Mol Pharmacol; 2019 Jan; 95(1):120-126. PubMed ID: 30397001
[TBL] [Abstract][Full Text] [Related]
19. Induction of human UDP-glucuronosyltransferase 1A1 by cortisol-GR.
Usui T; Kuno T; Mizutani T
Mol Biol Rep; 2006 Jun; 33(2):91-6. PubMed ID: 16817017
[TBL] [Abstract][Full Text] [Related]
20. Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter.
Chen Y; Ferguson SS; Negishi M; Goldstein JA
Mol Pharmacol; 2003 Aug; 64(2):316-24. PubMed ID: 12869636
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]