BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

689 related articles for article (PubMed ID: 18174526)

  • 1. Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
    Martinez SC; Tanabe K; Cras-Méneur C; Abumrad NA; Bernal-Mizrachi E; Permutt MA
    Diabetes; 2008 Apr; 57(4):846-59. PubMed ID: 18174526
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
    Wang W; Liu Y; Chen Y; Cao C; Xiang Y; Zhang D; Han L; Zhao H; Liu G
    Peptides; 2010 Feb; 31(2):307-14. PubMed ID: 19944124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling.
    Li XJ; Guo QH; Wang X; Xue B; Sun LQ; Meng QT; Lu JM; Mu YM
    Chin Med J (Engl); 2012 May; 125(10):1695-702. PubMed ID: 22800886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
    Ladrière L; Igoillo-Esteve M; Cunha DA; Brion JP; Bugliani M; Marchetti P; Eizirik DL; Cnop M
    J Clin Endocrinol Metab; 2010 Mar; 95(3):1442-9. PubMed ID: 20080856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis.
    Cheong MW; Kuo LH; Cheng YN; Tsai PJ; Ho LC; Tai HC; Chiu WT; Chen SH; Lu PJ; Shan YS; Chuang LM; Tsai YS
    J Mol Med (Berl); 2015 Jul; 93(7):807-18. PubMed ID: 25737480
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.
    Sommerweiss D; Gorski T; Richter S; Garten A; Kiess W
    Biochem Biophys Res Commun; 2013 Nov; 441(4):770-6. PubMed ID: 24189472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activation.
    Mayer CM; Belsham DD
    Endocrinology; 2010 Feb; 151(2):576-85. PubMed ID: 19952270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways.
    Hao F; Kang J; Cao Y; Fan S; Yang H; An Y; Pan Y; Tie L; Li X
    Apoptosis; 2015 Nov; 20(11):1420-32. PubMed ID: 26330141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis.
    Karaskov E; Scott C; Zhang L; Teodoro T; Ravazzola M; Volchuk A
    Endocrinology; 2006 Jul; 147(7):3398-407. PubMed ID: 16601139
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.
    Tanabe K; Liu Y; Hasan SD; Martinez SC; Cras-Méneur C; Welling CM; Bernal-Mizrachi E; Tanizawa Y; Rhodes CJ; Zmuda E; Hai T; Abumrad NA; Permutt MA
    PLoS One; 2011 Apr; 6(4):e18146. PubMed ID: 21541314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
    Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
    J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.
    Lai E; Bikopoulos G; Wheeler MB; Rozakis-Adcock M; Volchuk A
    Am J Physiol Endocrinol Metab; 2008 Mar; 294(3):E540-50. PubMed ID: 18198352
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.
    Martinez SC; Cras-Méneur C; Bernal-Mizrachi E; Permutt MA
    Diabetes; 2006 Jun; 55(6):1581-91. PubMed ID: 16731820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDLs protect the MIN6 insulinoma cell line against tunicamycin-induced apoptosis without inhibiting ER stress and without restoring ER functionality.
    Puyal J; Pétremand J; Dubuis G; Rummel C; Widmann C
    Mol Cell Endocrinol; 2013 Dec; 381(1-2):291-301. PubMed ID: 23994023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z; Lv J; Luo Y; Lin Y; Zhu Y; Nie J; Yang T; Sun Y; Han X
    Endocrinology; 2009 Dec; 150(12):5284-93. PubMed ID: 19837872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes.
    Guo W; Wong S; Xie W; Lei T; Luo Z
    Am J Physiol Endocrinol Metab; 2007 Aug; 293(2):E576-86. PubMed ID: 17519282
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.
    Kharroubi I; Ladrière L; Cardozo AK; Dogusan Z; Cnop M; Eizirik DL
    Endocrinology; 2004 Nov; 145(11):5087-96. PubMed ID: 15297438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.
    Akerfeldt MC; Howes J; Chan JY; Stevens VA; Boubenna N; McGuire HM; King C; Biden TJ; Laybutt DR
    Diabetes; 2008 Nov; 57(11):3034-44. PubMed ID: 18591394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis.
    Omae N; Ito M; Hase S; Nagasawa M; Ishiyama J; Ide T; Murakami K
    Mol Cell Endocrinol; 2012 Jan; 348(1):297-304. PubMed ID: 21945815
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.
    Pirot P; Ortis F; Cnop M; Ma Y; Hendershot LM; Eizirik DL; Cardozo AK
    Diabetes; 2007 Apr; 56(4):1069-77. PubMed ID: 17395747
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.