These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 18175303)

  • 1. Identification of putative binding sites of P-glycoprotein based on its homology model.
    Globisch C; Pajeva IK; Wiese M
    ChemMedChem; 2008 Feb; 3(2):280-95. PubMed ID: 18175303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites.
    Vandevuer S; Van Bambeke F; Tulkens PM; Prévost M
    Proteins; 2006 May; 63(3):466-78. PubMed ID: 16463278
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of the inward- and outward-open homology models and ligand binding of human P-glycoprotein.
    Pajeva IK; Globisch C; Wiese M
    FEBS J; 2009 Dec; 276(23):7016-26. PubMed ID: 19878299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2005 Aug; 44(30):10250-8. PubMed ID: 16042402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2007 Aug; 46(32):9328-36. PubMed ID: 17636884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket.
    Loo TW; Bartlett MC; Clarke DM
    Biochem J; 2006 Oct; 399(2):351-9. PubMed ID: 16813563
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Residue G346 in transmembrane segment six is involved in inter-domain communication in P-glycoprotein.
    Storm J; O'Mara ML; Crowley EH; Peall J; Tieleman DP; Kerr ID; Callaghan R
    Biochemistry; 2007 Sep; 46(35):9899-910. PubMed ID: 17696319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2004 Sep; 43(38):12081-9. PubMed ID: 15379547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N; Moitra K; Silver C; Ghosh P; Chattopadhyay A; Dey S
    Biochemistry; 2006 Feb; 45(8):2739-51. PubMed ID: 16489767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces.
    Mornon JP; Lehn P; Callebaut I
    Cell Mol Life Sci; 2008 Aug; 65(16):2594-612. PubMed ID: 18597042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-directed disulfide mapping of residues contributing to the Ca2+ and K+ binding pocket of the NCKX2 Na+/Ca2+-K+ exchanger.
    Kinjo TG; Kang K; Szerencsei RT; Winkfein RJ; Schnetkamp PP
    Biochemistry; 2005 May; 44(21):7787-95. PubMed ID: 15909993
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Refinement of 3D models of horseradish peroxidase isoenzyme C: predictions of 2D NMR assignments and substrate binding sites.
    Zhao D; Gilfoyle DJ; Smith AT; Loew GH
    Proteins; 1996 Oct; 26(2):204-16. PubMed ID: 8916228
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional and structural roles of critical amino acids within the"N", "P", and "A" domains of the Ca2+ ATPase (SERCA) headpiece.
    Ma H; Lewis D; Xu C; Inesi G; Toyoshima C
    Biochemistry; 2005 Jun; 44(22):8090-100. PubMed ID: 15924428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5).
    Ravna AW; Sylte I; Sager G
    Eur J Med Chem; 2008 Nov; 43(11):2557-67. PubMed ID: 18313803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.
    Rothnie A; Storm J; McMahon R; Taylor A; Kerr ID; Callaghan R
    FEBS Lett; 2005 Jul; 579(18):3984-90. PubMed ID: 16004994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5).
    Ravna AW; Sylte I; Sager G
    Theor Biol Med Model; 2007 Sep; 4():33. PubMed ID: 17803828
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modelling and mutational evidence identify the substrate binding site and functional elements in APC amino acid transporters.
    Vangelatos I; Vlachakis D; Sophianopoulou V; Diallinas G
    Mol Membr Biol; 2009 Aug; 26(5):356-70. PubMed ID: 19670073
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4).
    Ravna AW; Sager G
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3481-3. PubMed ID: 18513968
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1.
    Qin L; Zheng J; Grant CE; Jia Z; Cole SP; Deeley RG
    Biochemistry; 2008 Dec; 47(52):13952-65. PubMed ID: 19063607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease.
    Popp C; Gorboulev V; Müller TD; Gorbunov D; Shatskaya N; Koepsell H
    Mol Pharmacol; 2005 May; 67(5):1600-11. PubMed ID: 15662044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.