BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 18175805)

  • 1. Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization.
    Giganti A; Rodriguez M; Fould B; Moulharat N; Cogé F; Chomarat P; Galizzi JP; Valet P; Saulnier-Blache JS; Boutin JA; Ferry G
    J Biol Chem; 2008 Mar; 283(12):7776-89. PubMed ID: 18175805
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of autotaxin production or activity blocks lysophosphatidylcholine-induced migration of human breast cancer and melanoma cells.
    Gaetano CG; Samadi N; Tomsig JL; Macdonald TL; Lynch KR; Brindley DN
    Mol Carcinog; 2009 Sep; 48(9):801-9. PubMed ID: 19204929
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid.
    Kishi Y; Okudaira S; Tanaka M; Hama K; Shida D; Kitayama J; Yamori T; Aoki J; Fujimaki T; Arai H
    J Biol Chem; 2006 Jun; 281(25):17492-17500. PubMed ID: 16627485
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
    Saunders LP; Cao W; Chang WC; Albright RA; Braddock DT; De La Cruz EM
    J Biol Chem; 2011 Aug; 286(34):30130-41. PubMed ID: 21719699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cyclic phosphatidic acid is produced by autotaxin in blood.
    Tsuda S; Okudaira S; Moriya-Ito K; Shimamoto C; Tanaka M; Aoki J; Arai H; Murakami-Murofushi K; Kobayashi T
    J Biol Chem; 2006 Sep; 281(36):26081-8. PubMed ID: 16837466
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma.
    Wu JM; Xu Y; Skill NJ; Sheng H; Zhao Z; Yu M; Saxena R; Maluccio MA
    Mol Cancer; 2010 Mar; 9():71. PubMed ID: 20356387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and biochemical characterization of a novel autotaxin isoform, ATXδ, with a four-amino acid deletion.
    Hashimoto T; Okudaira S; Igarashi K; Hama K; Yatomi Y; Aoki J
    J Biochem; 2012 Jan; 151(1):89-97. PubMed ID: 21994952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase.
    Tokumura A; Majima E; Kariya Y; Tominaga K; Kogure K; Yasuda K; Fukuzawa K
    J Biol Chem; 2002 Oct; 277(42):39436-42. PubMed ID: 12176993
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX).
    East JE; Kennedy AJ; Tomsig JL; De Leon AR; Lynch KR; Macdonald TL
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7132-6. PubMed ID: 20951039
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.
    Gierse J; Thorarensen A; Beltey K; Bradshaw-Pierce E; Cortes-Burgos L; Hall T; Johnston A; Murphy M; Nemirovskiy O; Ogawa S; Pegg L; Pelc M; Prinsen M; Schnute M; Wendling J; Wene S; Weinberg R; Wittwer A; Zweifel B; Masferrer J
    J Pharmacol Exp Ther; 2010 Jul; 334(1):310-7. PubMed ID: 20392816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity.
    Ferguson CG; Bigman CS; Richardson RD; van Meeteren LA; Moolenaar WH; Prestwich GD
    Org Lett; 2006 May; 8(10):2023-6. PubMed ID: 16671772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Large scale purification and characterization of recombinant human autotaxin/lysophospholipase D from mammalian cells.
    Song Y; Dilger E; Bell J; Barton WA; Fang X
    BMB Rep; 2010 Aug; 43(8):541-6. PubMed ID: 20797316
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.
    Gajewiak J; Tsukahara R; Fujiwara Y; Tigyi G; Prestwich GD
    Org Lett; 2008 Mar; 10(6):1111-4. PubMed ID: 18284246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid.
    Inoue M; Xie W; Matsushita Y; Chun J; Aoki J; Ueda H
    Neuroscience; 2008 Mar; 152(2):296-8. PubMed ID: 18280050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autotaxin/lysophospholipase D-mediated lysophosphatidic acid signaling is required to form distinctive large lysosomes in the visceral endoderm cells of the mouse yolk sac.
    Koike S; Keino-Masu K; Ohto T; Sugiyama F; Takahashi S; Masu M
    J Biol Chem; 2009 Nov; 284(48):33561-70. PubMed ID: 19808661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.
    Ferry G; Moulharat N; Pradère JP; Desos P; Try A; Genton A; Giganti A; Beucher-Gaudin M; Lonchampt M; Bertrand M; Saulnier-Blache JS; Tucker GC; Cordi A; Boutin JA
    J Pharmacol Exp Ther; 2008 Dec; 327(3):809-19. PubMed ID: 18755937
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of an activity-based probe for autotaxin.
    Cavalli S; Houben AJ; Albers HM; van Tilburg EW; de Ru A; Aoki J; van Veelen P; Moolenaar WH; Ovaa H
    Chembiochem; 2010 Nov; 11(16):2311-7. PubMed ID: 20941725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase.
    Pradère JP; Tarnus E; Grès S; Valet P; Saulnier-Blache JS
    Biochim Biophys Acta; 2007 Jan; 1771(1):93-102. PubMed ID: 17208043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate.
    Song J; Clair T; Noh JH; Eun JW; Ryu SY; Lee SN; Ahn YM; Kim SY; Lee SH; Park WS; Yoo NJ; Lee JY; Nam SW
    Biochem Biophys Res Commun; 2005 Nov; 337(3):967-75. PubMed ID: 16219296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis.
    Pamuklar Z; Federico L; Liu S; Umezu-Goto M; Dong A; Panchatcharam M; Fulkerson Z; Berdyshev E; Natarajan V; Fang X; van Meeteren LA; Moolenaar WH; Mills GB; Morris AJ; Smyth SS
    J Biol Chem; 2009 Mar; 284(11):7385-94. PubMed ID: 19139100
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.