BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

532 related articles for article (PubMed ID: 18178565)

  • 1. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.
    Zhai D; Jin C; Huang Z; Satterthwait AC; Reed JC
    J Biol Chem; 2008 Apr; 283(15):9580-6. PubMed ID: 18178565
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MCL-1 inhibits BAX in the absence of MCL-1/BAX Interaction.
    Germain M; Milburn J; Duronio V
    J Biol Chem; 2008 Mar; 283(10):6384-92. PubMed ID: 18089567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of the anti-apoptotic mechanism of Bcl-B.
    Zhai D; Ke N; Zhang H; Ladror U; Joseph M; Eichinger A; Godzik A; Ng SC; Reed JC
    Biochem J; 2003 Nov; 376(Pt 1):229-36. PubMed ID: 12921534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.
    Clohessy JG; Zhuang J; de Boer J; Gil-Gómez G; Brady HJ
    J Biol Chem; 2006 Mar; 281(9):5750-9. PubMed ID: 16380381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
    Gillissen B; Essmann F; Hemmati PG; Richter A; Richter A; Oztop I; Chinnadurai G; Dörken B; Daniel PT
    J Cell Biol; 2007 Nov; 179(4):701-15. PubMed ID: 18025305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
    O'Neill KL; Huang K; Zhang J; Chen Y; Luo X
    Genes Dev; 2016 Apr; 30(8):973-88. PubMed ID: 27056669
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins.
    Goodall KJ; Finch-Edmondson ML; van Vuuren J; Yeoh GC; Gentle IE; Vince JE; Ekert PG; Vaux DL; Callus BA
    PLoS One; 2016; 11(11):e0164003. PubMed ID: 27806040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S; Dai Y; Harada H; Dent P; Grant S
    Cancer Res; 2007 Jan; 67(2):782-91. PubMed ID: 17234790
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
    Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G
    Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
    Lindqvist LM; Heinlein M; Huang DC; Vaux DL
    Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8512-7. PubMed ID: 24912196
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.
    Vela L; Gonzalo O; Naval J; Marzo I
    J Biol Chem; 2013 Feb; 288(7):4935-46. PubMed ID: 23283967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K; O'Neill KL; Li J; Zhou W; Han N; Pang X; Wu W; Struble L; Borgstahl G; Liu Z; Zhang L; Luo X
    Cell Res; 2019 Nov; 29(11):942-952. PubMed ID: 31551537
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.
    Campbell S; Hazes B; Kvansakul M; Colman P; Barry M
    J Biol Chem; 2010 Feb; 285(7):4695-708. PubMed ID: 19955184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
    Uren RT; Dewson G; Chen L; Coyne SC; Huang DC; Adams JM; Kluck RM
    J Cell Biol; 2007 Apr; 177(2):277-87. PubMed ID: 17452531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist.
    Simmons MJ; Fan G; Zong WX; Degenhardt K; White E; Gélinas C
    Oncogene; 2008 Feb; 27(10):1421-8. PubMed ID: 17724464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC; Kanai M; Inoue-Yamauchi A; Tu HC; Huang Y; Ren D; Kim H; Takeda S; Reyna DE; Chan PM; Ganesan YT; Liao CP; Gavathiotis E; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2015 Oct; 17(10):1270-81. PubMed ID: 26344567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.