BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

520 related articles for article (PubMed ID: 18178565)

  • 21. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
    Willis SN; Chen L; Dewson G; Wei A; Naik E; Fletcher JI; Adams JM; Huang DC
    Genes Dev; 2005 Jun; 19(11):1294-305. PubMed ID: 15901672
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mcl-1(128-350) fragment induces apoptosis through direct interaction with Bax.
    Ménoret E; Gomez-Bougie P; Surget S; Trichet V; Oliver L; Pellat-Deceunynck C; Amiot M
    FEBS Lett; 2010 Feb; 584(3):487-92. PubMed ID: 19968986
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.
    Wang C; Youle RJ
    Oncogene; 2012 Jun; 31(26):3177-89. PubMed ID: 22056880
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Vesicular stomatitis virus induces apoptosis primarily through Bak rather than Bax by inactivating Mcl-1 and Bcl-XL.
    Pearce AF; Lyles DS
    J Virol; 2009 Sep; 83(18):9102-12. PubMed ID: 19587033
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
    van Delft MF; Wei AH; Mason KD; Vandenberg CJ; Chen L; Czabotar PE; Willis SN; Scott CL; Day CL; Cory S; Adams JM; Roberts AW; Huang DC
    Cancer Cell; 2006 Nov; 10(5):389-99. PubMed ID: 17097561
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.
    Ferrer PE; Frederick P; Gulbis JM; Dewson G; Kluck RM
    PLoS One; 2012; 7(3):e31510. PubMed ID: 22442658
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Contribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax.
    Stehle D; Grimm M; Einsele-Scholz S; Ladwig F; Johänning J; Fischer G; Gillissen B; Schulze-Osthoff K; Essmann F
    Sci Rep; 2018 Aug; 8(1):12434. PubMed ID: 30127460
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Regulation of apoptosis by BH3 domains in a cell-free system.
    Cosulich SC; Worrall V; Hedge PJ; Green S; Clarke PR
    Curr Biol; 1997 Dec; 7(12):913-20. PubMed ID: 9382837
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DMFC (3,5-dimethyl-
    Xiang J; Wang Z; Liu Q; Li X; Sun J; Fung KP; Liu F
    Apoptosis; 2017 Mar; 22(3):381-392. PubMed ID: 27873035
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Context-dependent Bcl-2/Bak interactions regulate lymphoid cell apoptosis.
    Dai H; Meng XW; Lee SH; Schneider PA; Kaufmann SH
    J Biol Chem; 2009 Jul; 284(27):18311-22. PubMed ID: 19351886
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.
    Finnegan NM; Curtin JF; Prevost G; Morgan B; Cotter TG
    Br J Cancer; 2001 Jul; 85(1):115-21. PubMed ID: 11437412
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
    Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
    [TBL] [Abstract][Full Text] [Related]  

  • 34. How the Bcl-2 family of proteins interact to regulate apoptosis.
    van Delft MF; Huang DC
    Cell Res; 2006 Feb; 16(2):203-13. PubMed ID: 16474435
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pseudomonas exotoxin A-mediated apoptosis is Bak dependent and preceded by the degradation of Mcl-1.
    Du X; Youle RJ; FitzGerald DJ; Pastan I
    Mol Cell Biol; 2010 Jul; 30(14):3444-52. PubMed ID: 20457813
    [TBL] [Abstract][Full Text] [Related]  

  • 36. NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition.
    Shimazu T; Degenhardt K; Nur-E-Kamal A; Zhang J; Yoshida T; Zhang Y; Mathew R; White E; Inouye M
    Genes Dev; 2007 Apr; 21(8):929-41. PubMed ID: 17403773
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak.
    Pérez-Galán P; Roué G; Villamor N; Campo E; Colomer D
    Blood; 2007 May; 109(10):4441-9. PubMed ID: 17227835
    [TBL] [Abstract][Full Text] [Related]  

  • 38. MCL-1ES induces MCL-1L-dependent BAX- and BAK-independent mitochondrial apoptosis.
    Kim JH; Bae J
    PLoS One; 2013; 8(11):e79626. PubMed ID: 24260268
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
    Lindenboim L; Blacher E; Borner C; Stein R
    Cell Death Differ; 2010 Feb; 17(2):346-59. PubMed ID: 19816507
    [TBL] [Abstract][Full Text] [Related]  

  • 40. M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression.
    Hasan Z; Ashraf M; Tayyebi A; Hussain R
    BMC Microbiol; 2006 Sep; 6():78. PubMed ID: 16978419
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 26.