195 related articles for article (PubMed ID: 18183931)
1. Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
Hallgren O; Aits S; Brest P; Gustafsson L; Mossberg AK; Wullt B; Svanborg C
Adv Exp Med Biol; 2008; 606():217-40. PubMed ID: 18183931
[TBL] [Abstract][Full Text] [Related]
2. alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.
Pettersson-Kastberg J; Mossberg AK; Trulsson M; Yong YJ; Min S; Lim Y; O'Brien JE; Svanborg C; Mok KH
J Mol Biol; 2009 Dec; 394(5):994-1010. PubMed ID: 19766653
[TBL] [Abstract][Full Text] [Related]
3. Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.
Mossberg AK; Hun Mok K; Morozova-Roche LA; Svanborg C
FEBS J; 2010 Nov; 277(22):4614-25. PubMed ID: 20977665
[TBL] [Abstract][Full Text] [Related]
4. Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
Svensson M; Fast J; Mossberg AK; Düringer C; Gustafsson L; Hallgren O; Brooks CL; Berliner L; Linse S; Svanborg C
Protein Sci; 2003 Dec; 12(12):2794-804. PubMed ID: 14627739
[TBL] [Abstract][Full Text] [Related]
5. HAMLET: functional properties and therapeutic potential.
Ho C S J; Rydström A; Trulsson M; Bålfors J; Storm P; Puthia M; Nadeem A; Svanborg C
Future Oncol; 2012 Oct; 8(10):1301-13. PubMed ID: 23130929
[TBL] [Abstract][Full Text] [Related]
6. HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.
Hallgren O; Gustafsson L; Irjala H; Selivanova G; Orrenius S; Svanborg C
Apoptosis; 2006 Feb; 11(2):221-33. PubMed ID: 16502260
[TBL] [Abstract][Full Text] [Related]
7. alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
Pettersson J; Mossberg AK; Svanborg C
Biochem Biophys Res Commun; 2006 Jun; 345(1):260-70. PubMed ID: 16678133
[TBL] [Abstract][Full Text] [Related]
8. HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death.
Aits S; Gustafsson L; Hallgren O; Brest P; Gustafsson M; Trulsson M; Mossberg AK; Simon HU; Mograbi B; Svanborg C
Int J Cancer; 2009 Mar; 124(5):1008-19. PubMed ID: 19048621
[TBL] [Abstract][Full Text] [Related]
9. HAMLET - A protein-lipid complex with broad tumoricidal activity.
Ho JCS; Nadeem A; Svanborg C
Biochem Biophys Res Commun; 2017 Jan; 482(3):454-458. PubMed ID: 28212731
[TBL] [Abstract][Full Text] [Related]
10. Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity.
Ho CS; Rydstrom A; Manimekalai MS; Svanborg C; Grüber G
PLoS One; 2012; 7(12):e53051. PubMed ID: 23300861
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.
Nakamura T; Aizawa T; Kariya R; Okada S; Demura M; Kawano K; Makabe K; Kuwajima K
J Biol Chem; 2013 May; 288(20):14408-14416. PubMed ID: 23580643
[TBL] [Abstract][Full Text] [Related]
12. A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model.
Xiao Z; Mak A; Koch K; Moore RB
BJU Int; 2013 Jul; 112(2):E201-10. PubMed ID: 23356235
[TBL] [Abstract][Full Text] [Related]
13. Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.
Ho JC; Storm P; Rydström A; Bowen B; Alsin F; Sullivan L; Ambite I; Mok KH; Northen T; Svanborg C
J Biol Chem; 2013 Jun; 288(24):17460-71. PubMed ID: 23629662
[TBL] [Abstract][Full Text] [Related]
14. A novel method for preparation of HAMLET-like protein complexes.
Permyakov SE; Knyazeva EL; Leonteva MV; Fadeev RS; Chekanov AV; Zhadan AP; Håkansson AP; Akatov VS; Permyakov EA
Biochimie; 2011 Sep; 93(9):1495-501. PubMed ID: 21596091
[TBL] [Abstract][Full Text] [Related]
15. Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.
Mercer N; Ramakrishnan B; Boeggeman E; Qasba PK
PLoS One; 2011; 6(10):e26093. PubMed ID: 22016817
[TBL] [Abstract][Full Text] [Related]
16. Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components.
Rath EM; Duff AP; Håkansson AP; Vacher CS; Liu GJ; Knott RB; Church WB
J Pharm Pharm Sci; 2015; 18(4):773-824. PubMed ID: 26626257
[TBL] [Abstract][Full Text] [Related]
17. The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in
Roche-Hakansson H; Vansarla G; Marks LR; Hakansson AP
J Biol Chem; 2019 Dec; 294(51):19511-19522. PubMed ID: 31694917
[TBL] [Abstract][Full Text] [Related]
18. Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.
Xie Y; Min S; Harte NP; Kirk H; O'Brien JE; Voorheis HP; Svanborg C; Hun Mok K
Proteins; 2013 Jan; 81(1):1-17. PubMed ID: 22777854
[TBL] [Abstract][Full Text] [Related]
19. Apoptosis-like death in bacteria induced by HAMLET, a human milk lipid-protein complex.
Hakansson AP; Roche-Hakansson H; Mossberg AK; Svanborg C
PLoS One; 2011 Mar; 6(3):e17717. PubMed ID: 21423701
[TBL] [Abstract][Full Text] [Related]
20. HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy.
Gustafsson L; Hallgren O; Mossberg AK; Pettersson J; Fischer W; Aronsson A; Svanborg C
J Nutr; 2005 May; 135(5):1299-303. PubMed ID: 15867328
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
