BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

908 related articles for article (PubMed ID: 18187584)

  • 1. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
    Roth A; Looser R; Kaufmann M; Meyer UA
    Pharmacogenet Genomics; 2008 Apr; 18(4):325-37. PubMed ID: 18334917
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
    Dvorák Z; Maurel P; Vilarem MJ; Ulrichová J; Modrianský M
    Cell Biol Toxicol; 2007 Mar; 23(2):63-73. PubMed ID: 16964586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
    Wyde ME; Bartolucci E; Ueda A; Zhang H; Yan B; Negishi M; You L
    Mol Pharmacol; 2003 Aug; 64(2):474-81. PubMed ID: 12869653
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.
    Moreau A; Vilarem MJ; Maurel P; Pascussi JM
    Mol Pharm; 2008; 5(1):35-41. PubMed ID: 18159929
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver.
    Al-Dosari MS; Knapp JE; Liu D
    Mol Pharm; 2006; 3(3):322-8. PubMed ID: 16749864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
    Slatter JG; Cheng O; Cornwell PD; de Souza A; Rockett J; Rushmore T; Hartley D; Evers R; He Y; Dai X; Hu R; Caguyong M; Roberts CJ; Castle J; Ulrich RG
    Xenobiotica; 2006; 36(10-11):902-37. PubMed ID: 17118914
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S; Huang W; Staudinger JL; Tan K; Cole TJ; Moore DD; Strobel HW
    Drug Metab Dispos; 2007 Jan; 35(1):36-42. PubMed ID: 17020958
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP) but not PPAR-interacting protein (PRIP) is required for nuclear translocation of constitutive androstane receptor in mouse liver.
    Guo D; Sarkar J; Ahmed MR; Viswakarma N; Jia Y; Yu S; Sambasiva Rao M; Reddy JK
    Biochem Biophys Res Commun; 2006 Aug; 347(2):485-95. PubMed ID: 16828057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR).
    Echchgadda I; Song CS; Oh TS; Cho SH; Rivera OJ; Chatterjee B
    Mech Ageing Dev; 2004; 125(10-11):733-45. PubMed ID: 15541768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activators of the rat pregnane X receptor differentially modulate hepatic and intestinal gene expression.
    Hartley DP; Dai X; He YD; Carlini EJ; Wang B; Huskey SE; Ulrich RG; Rushmore TH; Evers R; Evans DC
    Mol Pharmacol; 2004 May; 65(5):1159-71. PubMed ID: 15102944
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PXR and CAR in energy metabolism.
    Wada T; Gao J; Xie W
    Trends Endocrinol Metab; 2009 Aug; 20(6):273-9. PubMed ID: 19595610
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
    Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
    Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.
    Aouabdi S; Gibson G; Plant N
    Drug Metab Dispos; 2006 Jan; 34(1):138-44. PubMed ID: 16243957
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
    Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
    Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
    Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
    Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses.
    Wyde ME; Kirwan SE; Zhang F; Laughter A; Hoffman HB; Bartolucci-Page E; Gaido KW; Yan B; You L
    Toxicol Sci; 2005 Aug; 86(2):281-90. PubMed ID: 15901914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor.
    Köhle C; Bock KW
    Biochem Pharmacol; 2009 Feb; 77(4):689-99. PubMed ID: 18606396
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.